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PDB: 64 件

4W2H
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4V73
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre5a)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
6GXM
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Cryo-EM structure of an E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and Pint-tRNA (State II)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N.
登録日2018-06-27
公開日2018-08-22
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
4W2G
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BU of 4w2g by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4W2F
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BU of 4w2f by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
7B7D
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Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N.
登録日2020-12-10
公開日2021-03-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome
To Be Published
6YSR
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Structure of the P+9 stalled ribosome complex
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
登録日2020-04-23
公開日2020-08-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6YSU
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Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
登録日2020-04-23
公開日2020-08-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
1MJ1
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FITTING THE TERNARY COMPLEX OF EF-Tu/tRNA/GTP AND RIBOSOMAL PROTEINS INTO A 13 A CRYO-EM MAP OF THE COLI 70S RIBOSOME
分子名称: Elongation Factor Tu, L11 ribosomal protein, Phe-tRNA, ...
著者Stark, H, Rodnina, M.V, Wieden, H.-J, Zemlin, F, Wintermeyer, W, Vanheel, M.
登録日2002-08-26
公開日2002-11-01
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Ribosome Interactions of Aminoacyl-tRNA and Elongation Factor TU in the Codon Recognition Complex
Nat.Struct.Biol., 9, 2002
5LZB
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BU of 5lzb by Molmil
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the initial binding state (IB)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
3L0U
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The crystal structure of unmodified tRNAPhe from Escherichia coli
分子名称: MAGNESIUM ION, POTASSIUM ION, Unmodified tRNAPhe
著者Byrne, R.T, Konevega, A.L, Rodnina, M.V, Antson, A.A.
登録日2009-12-10
公開日2010-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structure of unmodified tRNAPhe from Escherichia coli
Nucleic Acids Res., 38, 2010
6YST
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BU of 6yst by Molmil
Structure of the P+9 ArfB-ribosome complex with P/E hybrid tRNA in the post-hydrolysis state
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
登録日2020-04-23
公開日2020-08-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6YSS
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BU of 6yss by Molmil
Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
登録日2020-04-23
公開日2020-08-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
8RG0
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BU of 8rg0 by Molmil
Structure of human eIF3 core from closed 48S translation initiation complex
分子名称: 18S rRNA, 40S ribosomal protein S13, 40S ribosomal protein S14, ...
著者Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N.
登録日2023-12-13
公開日2024-08-14
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
8PJ6
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BU of 8pj6 by Molmil
Structure of human 48S translation initiation complex with initiator tRNA, eIF1A and eIF3 (off-pathway)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N.
登録日2023-06-22
公開日2024-08-14
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
8PJ2
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Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N.
登録日2023-06-22
公開日2024-08-14
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
8PJ4
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Structure of human 48S translation initiation complex after eIF5 release (48S-4)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N.
登録日2023-06-22
公開日2024-08-14
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
8PJ5
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Structure of human 48S translation initiation complex after eIF2 release prior 60S subunit joining (48S-5)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N.
登録日2023-06-22
公開日2024-08-14
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
8PJ1
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Structure of human 48S translation initiation complex in open codon scanning state (48S-1)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N.
登録日2023-06-22
公開日2024-08-14
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
8PJ3
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Structure of human 48S translation initiation complex upon transfer of initiator tRNA to eIF5B (48S-3)
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N.
登録日2023-06-22
公開日2024-08-14
最終更新日2024-10-02
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for translational control by the human 48S initiation complex.
Nat.Struct.Mol.Biol., 2024
4V76
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BU of 4v76 by Molmil
E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post2a)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V72
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in hybrid pre-translocation state (pre4)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V78
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate post-translocation state (post3a)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V71
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre2)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013
4V75
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E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic post-translocation state (post1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H.
登録日2013-10-14
公開日2014-07-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Energy barriers and driving forces in tRNA translocation through the ribosome.
Nat.Struct.Mol.Biol., 20, 2013

 

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