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PDB: 239 件
3UTS
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BU of 3uts by Molmil
1E6-A*0201-ALWGPDPAAA Complex, Monoclinic
分子名称: 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
登録日2011-11-26
公開日2012-01-25
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (2.712 Å)
主引用文献Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3UTQ
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BU of 3utq by Molmil
Human HLA-A*0201-ALWGPDPAAA
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
登録日2011-11-26
公開日2012-01-25
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
4WDI
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BU of 4wdi by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2014-09-08
公開日2015-06-24
最終更新日2015-07-01
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
7Q9B
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BU of 7q9b by Molmil
MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-11-12
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q99
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BU of 7q99 by Molmil
MHC Class I A02 Allele presenting NLSALGIFST, in complex with Mel5 TCR
分子名称: 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-11-12
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q98
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BU of 7q98 by Molmil
MHC Class I A02 Allele presenting NLSALGIFST
分子名称: 1,2-ETHANEDIOL, ASN-LEU-SER-ALA-LEU-GLY-ILE-PHE-SER-THR, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Sewell, A.K.
登録日2021-11-12
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
7Q9A
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BU of 7q9a by Molmil
MHC Class I A02 Allele presenting LLLGIGILVL, in complex with Mel5 TCR
分子名称: Beta-2-microglobulin, GLYCEROL, Human Mel5 T Cell Receptor, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-11-12
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023
6TMO
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BU of 6tmo by Molmil
Structure determination of an enhanced affinity TCR, a24b17, in complex with HLA-A*02:01 presenting a MART-1 peptide, EAAGIGILTV
分子名称: 1,2-ETHANEDIOL, Alpha chain of engineered high affinity T-cell receptor, Beta chain of high affinity engineered T-cell receptor, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2019-12-05
公開日2020-10-07
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy.
Mol Ther Oncolytics, 18, 2020
2HP4
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BU of 2hp4 by Molmil
Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor
分子名称: GLYCEROL, SULFATE ION, T-cell surface glycoprotein CD8 alpha chain
著者Rizkallah, P.J, Cole, D.K, Jakobsen, B.K, Boulter, J.M, Glick, M, Gao, G.F.
登録日2006-07-17
公開日2007-02-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor
Proteins, 67, 2007
6QLB
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BU of 6qlb by Molmil
Calpain small subunit 1, RNA-binding protein Hfq
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, CALCIUM ION, ...
著者Rizkallah, P.J, Cresser-Brown, J.O.
登録日2019-01-31
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Calpain small subunit 1, RNA-binding protein Hfq
Acta Crystallogr.,Sect.F, 2020
6R0E
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BU of 6r0e by Molmil
Structure of F11TCR in complex with DR1 MHC Class II presenting PKYVKQNTLKLAT
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, F11-TCR Alpha Chain, ...
著者Rizkallah, P.J, Greenshields-Watson, A.L.
登録日2019-03-12
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献CD4+T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features.
Cell Rep, 32, 2020
4U1H
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BU of 4u1h by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1L
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BU of 4u1l by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1N
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BU of 4u1n by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1S
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BU of 4u1s by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-16
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1K
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BU of 4u1k by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
3UTP
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BU of 3utp by Molmil
1E6 TCR specific for HLA-A*0201-ALWGPDPAAA
分子名称: 1E6 TCR alpha chain, 1E6 TCR beta chain, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M.
登録日2011-11-26
公開日2012-01-25
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (2.574 Å)
主引用文献Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
4U1J
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BU of 4u1j by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
3UTT
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BU of 3utt by Molmil
1E6-A*0201-ALWGPDPAAA Complex, Triclinic
分子名称: 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M, Rossjohn, J, Gras, S.
登録日2011-11-26
公開日2012-01-25
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13, 2012
3DZW
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BU of 3dzw by Molmil
Structure of Narcissus pseudonarcissus lectin complex with Mannobiose at 1.7 A resolution, form II
分子名称: Agglutinin, PHOSPHATE ION, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose
著者Rizkallah, P.J, Ozbey, S, Sauerborn, M.K.
登録日2008-07-30
公開日2009-08-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of Narcissus pseudonarcissus lectin complex with Mannobiose at 1.7 A resolution, form II
To be Published
7OP2
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BU of 7op2 by Molmil
Chadox1/ Chimpanzee adenovirus Y25 fiber knob protein
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Rizkallah, P.J, Baker, A.T, Parker, A.L, Teijeira Crespo, A, Lipka-Lloyd, M.
登録日2021-05-28
公開日2021-06-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献ChAdOx1 interacts with CAR and PF4 with implications for thrombosis with thrombocytopenia syndrome.
Sci Adv, 7, 2021
7P3E
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BU of 7p3e by Molmil
MHC I A02 Allele presenting YLQLRTFLL
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, IODIDE ION, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-07-07
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
7P3D
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BU of 7p3d by Molmil
MHC I A02 Allele presenting YLQPRTFLL
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-07-07
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
7PBE
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BU of 7pbe by Molmil
Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-08-02
公開日2022-04-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
7ZUC
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BU of 7zuc by Molmil
Human Major Histocompatibility Complex A2 allele presenting LLLGIGILV
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-LEU-LEU-GLY-ILE-GLY-ILE-LEU-VAL, ...
著者Rizkallah, P.J, Wall, A, Sewell, A.K, Fuller, A.
登録日2022-05-12
公開日2023-05-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.
Cell, 186, 2023

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件を2024-07-10に公開中

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