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PDB: 23 件

4IZM
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BU of 4izm by Molmil
Crystal structure of GltPh L66C-S300C mutant crosslinked with divalent mercury
分子名称: 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, MERCURY (II) ION, ...
著者Reyes, N, Boudker, O.
登録日2013-01-30
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Binding thermodynamics of a glutamate transporter homolog.
Nat.Struct.Mol.Biol., 20, 2013
3KBC
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BU of 3kbc by Molmil
Crystal structure of GltPh K55C-A364C mutant crosslinked with divalent mercury
分子名称: 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, MERCURY (II) ION, ...
著者Reyes, N, Ginter, C, Boudker, O.
登録日2009-10-20
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Transport mechanism of a bacterial homologue of glutamate transporters.
Nature, 462, 2009
7OIX
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BU of 7oix by Molmil
Structure of thermostable human MFSD2A in complex with thermostable human Sync2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Sodium-dependent lysophosphatidylcholine symporter 1, Syncytin-2, ...
著者Martinez-Molledo, M, Reyes, N.
登録日2021-05-12
公開日2022-06-01
最終更新日2022-06-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2.
Nat.Struct.Mol.Biol., 29, 2022
7NPW
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BU of 7npw by Molmil
Cryo-EM structure of Human excitatory amino acid transporters-1 (EAAT1) in potassium buffer
分子名称: Excitatory amino acid transporter 1
著者Kumar, A, Reyes, N.
登録日2021-02-28
公開日2021-10-13
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献The ion-coupling mechanism of human excitatory amino acid transporters.
Embo J., 41, 2022
7AWP
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BU of 7awp by Molmil
Structure of the thermostabilized EAAT1 cryst-II mutant in complex with rubidium and barium ions and the allosteric inhibitor UCPH101
分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, BARIUM ION, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ...
著者Canul-Tec, J.C, Legrand, P, Reyes, N.
登録日2020-11-08
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.91 Å)
主引用文献The ion-coupling mechanism of human excitatory amino acid transporters.
Embo J., 41, 2022
7AWM
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BU of 7awm by Molmil
Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP, three sodium ions and the allosteric inhibitor UCPH101
分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, BARIUM ION, ...
著者Canul-Tec, J.C, Legrand, P, Reyes, N.
登録日2020-11-08
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献The ion-coupling mechanism of human excitatory amino acid transporters.
Embo J., 41, 2022
7AWL
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BU of 7awl by Molmil
Structure of the thermostabilized EAAT1 cryst-II mutant in complex with barium and the allosteric inhibitor UCPH101
分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, BARIUM ION, Excitatory amino acid transporter 1, ...
著者Canul-Tec, J.C, Legrand, P, Reyes, N.
登録日2020-11-08
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献The ion-coupling mechanism of human excitatory amino acid transporters.
Embo J., 41, 2022
7AWQ
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BU of 7awq by Molmil
Structure of the thermostabilized EAAT1 cryst-E386Q mutant in complex with L-ASP, sodium ions and the allosteric inhibitor UCPH101
分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, BARIUM ION, ...
著者Canul-Tec, J.C, Legrand, P, Reyes, N.
登録日2020-11-08
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献The ion-coupling mechanism of human excitatory amino acid transporters.
Embo J., 41, 2022
7AWN
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BU of 7awn by Molmil
Structure of the thermostabilized EAAT1 cryst mutant in complex with rubidium and barium and the allosteric inhibitor UCPH101
分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, BARIUM ION, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ...
著者Canul-Tec, J.C, Legrand, P, Reyes, N.
登録日2020-11-08
公開日2021-10-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.92 Å)
主引用文献The ion-coupling mechanism of human excitatory amino acid transporters.
Embo J., 41, 2022
6Y90
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BU of 6y90 by Molmil
Structure of full-length CD20 in complex with Rituximab Fab
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, B-lymphocyte antigen CD20, CHOLESTEROL HEMISUCCINATE, ...
著者Kumar, A, Reyes, N.
登録日2020-03-06
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Binding mechanisms of therapeutic antibodies to human CD20.
Science, 369, 2020
6Y97
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BU of 6y97 by Molmil
Structure of full-length CD20 in complex with Obinutuzumab Fab
分子名称: B-lymphocyte antigen CD20, Obinutuzumab Fab heavy chain, Obinutuzumab Fab light chain
著者Kumar, A, Reyes, N.
登録日2020-03-06
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (4.33 Å)
主引用文献Binding mechanisms of therapeutic antibodies to human CD20.
Science, 369, 2020
6Y92
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BU of 6y92 by Molmil
Structure of full-length CD20 in complex with Ofatumumab Fab
分子名称: B-lymphocyte antigen CD20, CHOLESTEROL HEMISUCCINATE, Ofatumumab Fab heavy chain, ...
著者Kumar, A, Reyes, N.
登録日2020-03-06
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (4.73 Å)
主引用文献Binding mechanisms of therapeutic antibodies to human CD20.
Science, 369, 2020
6Y9A
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BU of 6y9a by Molmil
Structure of full-length CD20 in complex with Obinutuzumab Fab
分子名称: B-lymphocyte antigen CD20, Obinutuzumab Fab Light chain, Obinutuzumab Fab heavy chain
著者Kumar, A, Reyes, N.
登録日2020-03-06
公開日2020-08-26
最終更新日2020-09-16
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Binding mechanisms of therapeutic antibodies to human CD20.
Science, 369, 2020
8OUJ
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BU of 8ouj by Molmil
Heterotrimeric Complex of Human ASCT2 with Syncytin-1
分子名称: ALANINE, Neutral amino acid transporter B(0), Syncytin-1
著者Khare, S, Reyes, N.
登録日2023-04-23
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins.
Nat.Struct.Mol.Biol., 2024
8OUI
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BU of 8oui by Molmil
Complex of ASCT2 with Suppressyn
分子名称: ALANINE, Neutral amino acid transporter B(0), Suppressyn
著者Khare, S, Kumar, A, Reyes, N.
登録日2023-04-23
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins.
Nat.Struct.Mol.Biol., 2024
8OUD
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BU of 8oud by Molmil
Structure of the human neutral amino acid transporter ASCT2 in complex with nanobody 469
分子名称: ALANINE, CHOLESTEROL HEMISUCCINATE, Nanobody 469, ...
著者Canul-Tec, J, Reyes, N.
登録日2023-04-22
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins.
Nat.Struct.Mol.Biol., 2024
8OUH
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BU of 8ouh by Molmil
Complex of human ASCT2 with Syncytin-1
分子名称: ALANINE, Neutral amino acid transporter B(0), Syncytin-1
著者Khare, S, Reyes, N.
登録日2023-04-23
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins.
Nat.Struct.Mol.Biol., 2024
7PQQ
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BU of 7pqq by Molmil
Structure of thermostabilised human NTCP in complex with Megabody 91
分子名称: Anti-RON nanobody,Megabody 91,Glucosidase YgjK, Sodium/bile acid cotransporter
著者Goutam, K, Reyes, N.
登録日2021-09-18
公開日2022-05-18
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of sodium-dependent bile salt uptake into the liver.
Nature, 606, 2022
7PQG
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BU of 7pqg by Molmil
Structure of thermostabilised human NTCP in complex with nanobody 87
分子名称: Nanobody 87, Sodium/bile acid cotransporter
著者Goutam, K, Reyes, N.
登録日2021-09-21
公開日2022-05-18
最終更新日2022-07-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of sodium-dependent bile salt uptake into the liver.
Nature, 606, 2022
5LM4
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BU of 5lm4 by Molmil
Structure of the thermostalilized EAAT1 cryst-II mutant in complex with L-ASP and the allosteric inhibitor UCPH101
分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ...
著者Canul-Tec, J, Assal, R, Legrand, P, Reyes, N.
登録日2016-07-29
公開日2017-04-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017
5LLM
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BU of 5llm by Molmil
Structure of the thermostabilized EAAT1 cryst mutant in complex with L-ASP and the allosteric inhibitor UCPH101
分子名称: 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, ...
著者Canul-Tec, J, Assal, R, Legrand, P, Reyes, N.
登録日2016-07-27
公開日2017-04-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017
5MJU
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BU of 5mju by Molmil
Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve inhibitor TFB-TBOA and the allosteric inhibitor UCPH101
分子名称: (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid, 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1
著者Canul-Tec, J, Assal, R, Legrand, P, Reyes, N.
登録日2016-12-01
公開日2017-04-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017
5LLU
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BU of 5llu by Molmil
Structure of the thermostabilized EAAT1 cryst-II mutant in complex with L-ASP
分子名称: ASPARTIC ACID, Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1, SODIUM ION
著者Canul-Tec, J, Assal, R, Legrand, P, Reyes, N.
登録日2016-07-28
公開日2017-04-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structure and allosteric inhibition of excitatory amino acid transporter 1.
Nature, 544, 2017

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