4PGZ
| Structural basis of KIT activation by oncogenic mutations in the extracellular region reveals a zipper-like mechanism for ligand-dependent or oncogenic receptor tyrosine kinase activation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, Mast/stem cell growth factor receptor Kit | 著者 | Reshetnyak, A.V, Boggon, T.J, Lax, I, Schlessinger, J. | 登録日 | 2014-05-03 | 公開日 | 2015-03-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The strength and cooperativity of KIT ectodomain contacts determine normal ligand-dependent stimulation or oncogenic activation in cancer. Mol.Cell, 57, 2015
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7N00
| Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in complex with AUG-alpha | 分子名称: | ALK and LTK ligand 2, ALK tyrosine kinase receptor | 著者 | Reshetnyak, A.V, Myasnikov, A.G, Rossi, P, Miller, D.J, Kalodimos, C.G. | 登録日 | 2021-05-24 | 公開日 | 2021-11-24 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (2.27 Å) | 主引用文献 | Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021
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7MZY
| Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 673-986 | 分子名称: | ACETATE ION, ALK tyrosine kinase receptor | 著者 | Reshetnyak, A.V, Sowaileh, M, Miller, D.J, Rossi, P, Myasnikov, A.G, Kalodimos, C.G. | 登録日 | 2021-05-24 | 公開日 | 2021-11-24 | 最終更新日 | 2021-12-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Mechanism for the activation of the anaplastic lymphoma kinase receptor. Nature, 600, 2021
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3QAP
| Crystal structure of Natronomonas pharaonis sensory rhodopsin II in the ground state | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, EICOSANE, RETINAL, ... | 著者 | Gushchin, I, Reshetnyak, A, Borshchevskiy, V, Ishchenko, A, Round, E, Grudinin, S, Engelhard, M, Buldt, G, Gordeliy, V. | 登録日 | 2011-01-11 | 公開日 | 2011-09-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Active State of Sensory Rhodopsin II: Structural Determinants for Signal Transfer and Proton Pumping. J.Mol.Biol., 412, 2011
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3QDC
| Crystal structure of Natronomonas pharaonis sensory rhodopsin II in the active state | 分子名称: | 2,3-DI-PHYTANYL-GLYCEROL, EICOSANE, RETINAL, ... | 著者 | Gushchin, I, Reshetnyak, A, Borshchevskiy, V, Ishchenko, A, Round, E, Grudinin, S, Engelhard, M, Buldt, G, Gordeliy, V. | 登録日 | 2011-01-18 | 公開日 | 2011-09-14 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Active State of Sensory Rhodopsin II: Structural Determinants for Signal Transfer and Proton Pumping. J.Mol.Biol., 412, 2011
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7MZZ
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7MZW
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7MZX
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7MK7
| Augmentor domain of augmentor-beta | 分子名称: | ALK and LTK ligand 1,Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Krimmer, S.G, Reshetnyak, A.V, Puleo, D.E, Schlessinger, J. | 登録日 | 2021-04-21 | 公開日 | 2021-11-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.42815185 Å) | 主引用文献 | Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600, 2021
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