8T9P
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8U4I
| Structure of the HER4/NRG1b Homodimer Extracellular Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | Authors: | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | Deposit date: | 2023-09-10 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain To Be Published
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8U4J
| Structure of the HER4/BTC Homodimer Extracellular Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betacellulin, ... | Authors: | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | Deposit date: | 2023-09-10 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the HER4/BTC Homodimer Extracellular Domain To Be Published
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6VR0
| Agrobacterium Tumefaciens ADP-glucose pyrophosphorylase W106A | Descriptor: | GLYCEROL, Glucose-1-phosphate adenylyltransferase, SULFATE ION | Authors: | Mascarenhas, R.N, Liu, D, Ballicora, M, Iglesias, A, Asencion, M, Figueroa, C. | Deposit date: | 2020-02-06 | Release date: | 2021-02-17 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Agrobacterium Tumefaciens ADP-glucose pyrophosphorylase W106A To Be Published
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6EU5
| Leishmania major N-myristoyltransferase with bound myristoyl-CoA and inhibitor | Descriptor: | 4-[3-[(8~{a}~{R})-3,4,6,7,8,8~{a}-hexahydro-1~{H}-pyrrolo[1,2-a]pyrazin-2-yl]propyl]-2,6-bis(chloranyl)-~{N}-methyl-~{N}-(1,3,5-trimethylpyrazol-4-yl)benzenesulfonamide, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA | Authors: | Brenk, R, Kehrein, J, Kersten, C. | Deposit date: | 2017-10-27 | Release date: | 2019-02-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.496083 Å) | Cite: | How To Design Selective Ligands for Highly Conserved Binding Sites: A Case Study UsingN-Myristoyltransferases as a Model System. J.Med.Chem., 2019
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8U4K
| Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betacellulin, ... | Authors: | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | Deposit date: | 2023-09-10 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.27 Å) | Cite: | Structure of the HER2/HER4/BTC Heterodimer Extracellular Domain To Be Published
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8U4L
| Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... | Authors: | Trenker, R, Diwanji, D, Bingham, T, Verba, K.A, Jura, N. | Deposit date: | 2023-09-10 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | Structure of the HER2/HER4/NRG1b Heterodimer Extracellular Domain To Be Published
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6F56
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5KJZ
| Co-crystal structure of PKA RI alpha CNB-B mutant (G316R/A336T) with cGMP | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit | Authors: | Lorenz, R, Moon, E, Kim, J.J, Huang, G.Y, Kim, C, Herberg, F.W. | Deposit date: | 2016-06-20 | Release date: | 2017-06-28 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.347 Å) | Cite: | Mutations of PKA cyclic nucleotide-binding domains reveal novel aspects of cyclic nucleotide selectivity. Biochem. J., 474, 2017
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7AB5
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7AB4
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7AB3
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8QAG
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8QAH
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6HRV
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8QKD
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8QAI
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6HSJ
| Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA | Descriptor: | ACETATE ION, COENZYME A, GLYCEROL, ... | Authors: | Wierenga, R.K, Kiema, T.R, Thapa, C.J. | Deposit date: | 2018-10-01 | Release date: | 2019-01-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry. Biochem. J., 476, 2019
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6HSP
| Crystal structure of the zebrafish peroxisomal SCP2-thiolase (type-1) in complex with CoA and octanoyl-CoA | Descriptor: | COENZYME A, GLYCEROL, OCTANOYL-COENZYME A, ... | Authors: | Wierenga, R.K, Kiema, T.R, Thapa, C.J. | Deposit date: | 2018-10-01 | Release date: | 2019-01-02 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | The peroxisomal zebrafish SCP2-thiolase (type-1) is a weak transient dimer as revealed by crystal structures and native mass spectrometry. Biochem. J., 476, 2019
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8GJU
| Crystal structure of human methylmalonyl-CoA mutase (MMUT) in complex with methylmalonic acidemia type A protein (MMAA), coenzyme A, and GDP | Descriptor: | COENZYME A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Mascarenhas, R.M, Ruetz, M, Gouda, H, Yaw, M, Banerjee, R. | Deposit date: | 2023-03-16 | Release date: | 2023-08-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair. Nat Commun, 14, 2023
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6EWF
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4WYZ
| The crystal structure of the A109G mutant of RNase A in complex with 3'UMP | Descriptor: | 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-18 | Release date: | 2015-11-18 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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4WYP
| The crystal structure of the A109G mutant of RNase A in complex with 5'AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-17 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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4WYN
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3QSU
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