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PDB: 794 件

1QDS
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SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM)
分子名称: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Lambeir, A.M, Backmann, J, Ruiz-Sanz, J, Filimonov, V, Nielsen, J.E, Vriend, G, Kursula, I, Norledge, B.V, Wierenga, R.K.
登録日1999-07-10
公開日2000-12-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase.
Eur.J.Biochem., 267, 2000
1QP7
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
著者Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
登録日1999-06-01
公開日1999-06-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QPZ
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PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
著者Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
登録日1999-06-01
公開日1999-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QQA
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*GP*CP*GP*CP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
著者Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G.
登録日1999-06-01
公開日1999-06-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
1QVT
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CRYSTAL STRUCTURE OF THE MULTIDRUG BINDING TRANSCRIPTIONAL REPRESSOR QACR BOUND TO THE DRUG PROFLAVINE
分子名称: PROFLAVIN, SULFATE ION, Transcriptional regulator qacR
著者Schumacher, M.A, Miller, M.C, Brennan, R.G.
登録日2003-08-28
公開日2004-08-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein
Embo J., 23, 2004
1QFL
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BU of 1qfl by Molmil
BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA IN COMPLEX WITH A REACTION INTERMEDIATE.
分子名称: COENZYME A, PROTEIN (ACETOACETYL-COA THIOLASE), SULFATE ION
著者Modis, Y, Wierenga, R.K.
登録日1999-04-12
公開日2000-04-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism.
Structure Fold.Des., 7, 1999
1GU7
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Enoyl thioester reductase from Candida tropicalis
分子名称: ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH, B-SPECIFIC] 1,MITOCHONDRIAL, GLYCEROL, ...
著者Airenne, T.T, Torkko, J.M, Wierenga, R.K, Hiltunen, J.K.
登録日2002-01-24
公開日2003-03-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-Function Analysis of Enoyl Thioester Reductase Involved in Mitochondrial Maintenance
J.Mol.Biol., 327, 2003
1HNW
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BU of 1hnw by Molmil
STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH TETRACYCLINE
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Brodersen, D.E, Clemons Jr, W.M, Carter, A.P, Morgan-Warren, R, Wimberly, B.T, Ramakrishnan, V.
登録日2000-12-08
公開日2001-02-21
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.
Cell(Cambridge,Mass.), 103, 2000
1HR0
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BU of 1hr0 by Molmil
CRYSTAL STRUCTURE OF INITIATION FACTOR IF1 BOUND TO THE 30S RIBOSOMAL SUBUNIT
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Carter, A.P, Clemons Jr, W.M, Brodersen, D.E, Morgan-Warren, R.J, Wimberly, B.T, Ramakrishnan, V.
登録日2000-12-20
公開日2001-01-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of an initiation factor bound to the 30S ribosomal subunit.
Science, 291, 2001
4L9J
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BU of 4l9j by Molmil
Crystal structure of S. aureus MepR in DNA-binding conformation
分子名称: MepR
著者Birukou, I, Brennan, R.G.
登録日2013-06-18
公開日2013-09-11
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus.
MBio, 4, 2013
4L9T
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BU of 4l9t by Molmil
Crystal structure of MepR F27L mutant from multidrug resistant S. aureus clinical isolate
分子名称: MepR, SULFATE ION
著者Birukou, I, Brennan, R.G.
登録日2013-06-18
公開日2013-09-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus.
MBio, 4, 2013
5FB2
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BU of 5fb2 by Molmil
S. aureus MepR F27L Mutant bound to oligodeoxyribonucleotide
分子名称: DNA (5'-D(*CP*GP*TP*TP*A)-3'), GLYCEROL, MarR family regulatory protein
著者Birukou, I, Newman, C.E, Brennan, R.G.
登録日2015-12-13
公開日2016-12-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献S. aureus MepR F27L Mutant bound to oligodeoxyribonucleotide
To Be Published
4LLN
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BU of 4lln by Molmil
Crystal structure of S. aureus MepR-DNA complex
分子名称: MepR, Palindromized mepR operator sequence
著者Birukou, I, Brennan, R.G.
登録日2013-07-09
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.842 Å)
主引用文献Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR.
Nucleic Acids Res., 42, 2014
5FFZ
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BU of 5ffz by Molmil
S. aureus MepR bound to ethidium bromide
分子名称: ETHIDIUM, MarR family regulatory protein, POTASSIUM ION
著者Birukou, I, Newman, C.E, Brennan, R.G.
登録日2015-12-19
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.585 Å)
主引用文献S. aureus MepR bound to ethidium bromide
To Be Published
3RJP
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BU of 3rjp by Molmil
Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
分子名称: CovR
著者Horstmann, N.M, Brennan, R.G, Shelburne, S.A.
登録日2011-04-15
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
To be Published
1QCD
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BU of 1qcd by Molmil
CRYSTAL STRUCTURES OF ADENINE PHOSPHORIBOSYLTRANSFERASE FROM LEISHMANIA DONOVANI
分子名称: ADENINE PHOSPHORIBOSYLTRANSFERASE, SULFATE ION
著者Phillips, C.L, Ullman, B, Brennan, R.G, Hill, C.P.
登録日1999-05-01
公開日1999-07-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
EMBO J., 18, 1999
8QAB
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BU of 8qab by Molmil
X-ray crystal structure of a de novo designed antiparallel coiled-coil hexameric alpha-helical barrel with 4 heptad repeats, apCCHex
分子名称: 1-methoxy-2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethane, apCCHex
著者Naudin, E.N, Albanese, K.I, Petrenas, R, Woolfson, D.N.
登録日2023-08-22
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 20, 2024
8QAD
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BU of 8qad by Molmil
X-ray crystal structure of a de novo designed single-chain antiparallel 6-helix coiled-coil alpha-helical barrel, sc-apCC-6-LLIA
分子名称: DODECAETHYLENE GLYCOL, sc-apCC-6-LLIA
著者Albanese, K.I, Petrenas, R, Woolfson, D.N.
登録日2023-08-22
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 20, 2024
8QAF
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BU of 8qaf by Molmil
X-ray crystal structure of a de novo designed single-chain antiparallel 8-helix coiled-coil alpha-helical barrel, sc-apCC-8
分子名称: sc-apCC-8
著者Albanese, K.I, Petrenas, R, Woolfson, D.N.
登録日2023-08-22
公開日2024-07-03
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rationally seeded computational protein design of ɑ-helical barrels.
Nat.Chem.Biol., 20, 2024
4CSJ
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BU of 4csj by Molmil
The discovery of potent selective glucocorticoid receptor modulators, suitable for inhalation
分子名称: 1,2-ETHANEDIOL, GLUCOCORTICOID RECEPTOR, N-[(2S)-1-[[1-(4-fluorophenyl)indazol-4-yl]amino]propan-2-yl]-2,4,6-trimethyl-benzenesulfonamide, ...
著者Edman, K, Ahlgren, R, Bengtsson, M, Bladh, H, Backstrom, S, Dahmen, J, Henriksson, K, Hillertz, P, Hulikal, V, Jerre, A, Kinchin, L, Kase, C, Lepisto, M, Mile, I, Nilsson, S, Smailagic, A, Taylor, J, Tjornebo, A, Wissler, L, Hansson, T.
登録日2014-03-07
公開日2014-05-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Discovery of Potent and Selective Non-Steroidal Glucocorticoid Receptor Modulators, Suitable for Inhalation.
Bioorg.Med.Chem.Lett., 24, 2014
2X2G
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BU of 2x2g by Molmil
CRYSTALLOGRAPHIC BINDING STUDIES WITH AN ENGINEERED MONOMERIC VARIANT OF TRIOSEPHOSPHATE ISOMERASE
分子名称: 3-PHOSPHOGLYCERIC ACID, TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL
著者Salin, M, Kapetaniou, E.G, Vaismaa, M, Lajunen, M, Casteleijn, M.G, Neubauer, P, Salmon, L, Wierenga, R.
登録日2010-01-13
公開日2010-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic Binding Studies with an Engineered Monomeric Variant of Triosephosphate Isomerase
Acta Crystallogr.,Sect.D, 66, 2010
2X1U
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Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
分子名称: SULFATE ION, TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL
著者Salin, M, Kapetaniou, E.G, Vaismaa, M, Lajunen, M, Casteleijn, M.G, Neubauer, P, Salmon, L, Wierenga, R.
登録日2010-01-04
公開日2010-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystallographic Binding Studies with an Engineered Monomeric Variant of Triosephosphate Isomerase
Acta Crystallogr.,Sect.D, 66, 2010
2X1S
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Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase
分子名称: 3-SULFOPROPANOIC ACID, SULFATE ION, TRIOSEPHOSPHATE ISOMERASE, ...
著者Salin, M, Kapetaniou, E.G, Vaismaa, M, Lajunen, M, Castejeijn, M.G, Neubauer, P, Salmon, L, Wierenga, R.
登録日2010-01-04
公開日2010-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystallographic Binding Studies with an Engineered Monomeric Variant of Triosephosphate Isomerase
Acta Crystallogr.,Sect.D, 66, 2010
4XB4
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BU of 4xb4 by Molmil
Structure of the N-terminal domain of OCP binding canthaxanthin
分子名称: Orange carotenoid-binding protein, beta,beta-carotene-4,4'-dione
著者Kerfeld, C.A, Sutter, M, Leverenz, R.L.
登録日2014-12-16
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.544 Å)
主引用文献PHOTOSYNTHESIS. A 12 angstrom carotenoid translocation in a photoswitch associated with cyanobacterial photoprotection.
Science, 348, 2015
4XB5
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Structure of orange carotenoid protein binding canthaxanthin
分子名称: GLYCEROL, Orange carotenoid-binding protein, beta,beta-carotene-4,4'-dione
著者Kerfeld, C.A, Sutter, M, Leverenz, R.L.
登録日2014-12-16
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献PHOTOSYNTHESIS. A 12 angstrom carotenoid translocation in a photoswitch associated with cyanobacterial photoprotection.
Science, 348, 2015

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件を2024-09-18に公開中

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