6GJW
 
 | | Structure of XIAP-BIR1 domain in complex with an NF023 analog | | 分子名称: | 4-[[3-[[3-[(4,8-disulfonatonaphthalen-1-yl)carbamoyl]phenyl]carbamoylamino]phenyl]carbonylamino]naphthalene-1,5-disulfonate, E3 ubiquitin-protein ligase XIAP, ZINC ION | | 著者 | Sorrentino, L, Cossu, F, Malkoc, B, Zaffaroni, M, Milani, M, Mastrangelo, E. | | 登録日 | 2018-05-17 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1.
Chemistryopen, 8, 2019
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6QCI
 | | Structure of XIAP-BIR1 V86E mutant | | 分子名称: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... | | 著者 | Sorrentino, L, Cossu, F, Milani, M, Mastrangelo, E. | | 登録日 | 2018-12-28 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-Activity Relationship of NF023 Derivatives Binding to XIAP-BIR1.
Chemistryopen, 8, 2019
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7PF1
 | | UVC treated Human apoferritin | | 分子名称: | CHLORIDE ION, Ferritin heavy chain, N-terminally processed, ... | | 著者 | Renault, L, Depelteau, J.S, Briegel, A. | | 登録日 | 2021-08-11 | | 公開日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | | 主引用文献 | UVC inactivation of pathogenic samples suitable for cryo-EM analysis.
Commun Biol, 5, 2022
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5MIV
 | | G307E variant of murine Apoptosis Inducing Factor in complex with NAD+ | | 分子名称: | Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Sorrentino, L, Cossu, F, Aliverti, A, Milani, M, Mastrangelo, E. | | 登録日 | 2016-11-29 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
Biochem. Biophys. Res. Commun., 490, 2017
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5MIU
 | | G307E variant of Murine Apoptosis Inducing Factor (oxidized state) | | 分子名称: | Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Sorrentino, L, Cossu, F, Milani, M, Aliverti, A, Mastrangelo, E. | | 登録日 | 2016-11-29 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
Biochem. Biophys. Res. Commun., 490, 2017
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8PKD
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3U9Z
 | | Crystal structure between actin and a protein construct containing the first beta-thymosin domain of drosophila ciboulot (residues 2-58) with the three mutations N26D/Q27K/D28S | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Renault, L, Husson, C, Carlier, M.F, Didry, D. | | 登録日 | 2011-10-20 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly
Embo J., 31, 2012
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3U8X
 | | Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Renault, L, Husson, C, Carlier, M.F, Didry, D. | | 登録日 | 2011-10-17 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly
Embo J., 31, 2012
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3SJH
 | | Crystal Structure of a chimera containing the N-terminal domain (residues 8-29) of drosophila Ciboulot and the C-terminal domain (residues 18-44) of bovine Thymosin-beta4, bound to G-actin-ATP-Latrunculin A | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Renault, L, Husson, C, Carlier, M.F, Didry, D. | | 登録日 | 2011-06-21 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly
Embo J., 31, 2012
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3U9D
 | | Crystal Structure of a chimera containing the N-terminal domain (residues 8-24) of drosophila Ciboulot and the C-terminal domain (residues 13-44) of bovine Thymosin-beta4, bound to G-actin-ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Renault, L, Husson, C, Carlier, M.F, Didry, D. | | 登録日 | 2011-10-18 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly.
Embo J., 31, 2012
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1QN1
 | | SOLUTION STRUCTURE OF DESULFOVIBRIO GIGAS FERRICYTOCHROME C3, NMR, 15 STRUCTURES | | 分子名称: | CYTOCHROME C3, HEME C | | 著者 | Brennan, L, Messias, A.C, Legall, J, Turner, D.L, Xavier, A.V. | | 登録日 | 1999-10-11 | | 公開日 | 2000-10-12 | | 最終更新日 | 2019-11-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Network of Functional Cooperativities in Cytochromes C3 from Desulfovibrio Gigas: Solution Structures of the Oxidised and Reduced States
J.Mol.Biol., 298, 2000
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1A12
 | | REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN | | 分子名称: | REGULATOR OF CHROMOSOME CONDENSATION 1 | | 著者 | Renault, L, Nassar, N, Vetter, I, Becker, J, Roth, M, Wittinghofer, A. | | 登録日 | 1997-12-19 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller.
Nature, 392, 1998
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1KU1
 | | Crystal Structure of the Sec7 Domain of Yeast GEA2 | | 分子名称: | ARF guanine-nucleotide exchange factor 2 | | 著者 | Renault, L, Christova, P, Guibert, B, Pasqualato, S, Cherfils, J. | | 登録日 | 2002-01-20 | | 公開日 | 2002-03-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.
Biochemistry, 41, 2002
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1FL0
 | | CRYSTAL STRUCTURE OF THE EMAP2/RNA-BINDING DOMAIN OF THE P43 PROTEIN FROM HUMAN AMINOACYL-TRNA SYNTHETASE COMPLEX | | 分子名称: | ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II | | 著者 | Renault, L, Kerjan, P, Pasqualato, S, Menetrey, J, Robinson, J.-C, Kawaguchi, S, Vassylyev, D.G, Yokoyama, S, Mirande, M, Cherfils, J. | | 登録日 | 2000-08-11 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry.
EMBO J., 20, 2001
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1S9D
 | | ARF1[DELTA 1-17]-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN | | 分子名称: | 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE, ADP-Ribosylation Factor 1, Arno, ... | | 著者 | Renault, L, Guibert, B, Cherfils, J. | | 登録日 | 2004-02-04 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Snapshots of the Mechanism and Inhibition of a Guanine Nucleotide Exchange Factor
Nature, 426, 2003
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1R8S
 | | ARF1[DELTA1-17]-GDP IN COMPLEX WITH A SEC7 DOMAIN CARRYING THE MUTATION OF THE CATALYTIC GLUTAMATE TO LYSINE | | 分子名称: | ADP-ribosylation factor 1, Arno, BETA-MERCAPTOETHANOL, ... | | 著者 | Renault, L, Guibert, B, Cherfils, J. | | 登録日 | 2003-10-28 | | 公開日 | 2004-01-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
Nature, 426, 2003
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1E8E
 | | Solution Structure of Methylophilus methylotrophus Cytochrome c''. Insights into the Structural Basis of Haem-Ligand Detachment | | 分子名称: | CYTOCHROME C'', HEME C | | 著者 | Brennan, L, Turner, D.L, Fareleira, P, Santos, H. | | 登録日 | 2000-09-20 | | 公開日 | 2001-09-20 | | 最終更新日 | 2020-01-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Methylophilus Methylotrophus Cytochrome C": Insights Into the Structural Basis of Haem-Ligand Detachment
J.Mol.Biol., 308, 2001
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1I2M
 | | RAN-RCC1-SO4 COMPLEX | | 分子名称: | GTP-BINDING NUCLEAR PROTEIN RAN, REGULATOR OF CHROMOSOME CONDENSATION 1, SULFATE ION | | 著者 | Renault, L, Kuhlmann, J, Henkel, A, Wittinghofer, A. | | 登録日 | 2001-02-11 | | 公開日 | 2001-05-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structural basis for guanine nucleotide exchange on Ran by the regulator of chromosome condensation (RCC1).
Cell(Cambridge,Mass.), 105, 2001
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1R8Q
 | | FULL-LENGTH ARF1-GDP-MG IN COMPLEX WITH BREFELDIN A AND A SEC7 DOMAIN | | 分子名称: | 1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE, ADP-ribosylation factor 1, Arno, ... | | 著者 | Renault, L, Guibert, B, Cherfils, J. | | 登録日 | 2003-10-28 | | 公開日 | 2004-01-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
Nature, 426, 2003
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1R8M
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1X75
 | | CcdB:GyrA14 complex | | 分子名称: | Cytotoxic protein ccdB, DNA gyrase subunit A | | 著者 | Dao-Thi, M.H, Van Melderen, L, De Genst, E, Wyns, L, Loris, R. | | 登録日 | 2004-08-13 | | 公開日 | 2005-05-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular Basis of Gyrase Poisoning by the Addiction Toxin CcdB
J.Mol.Biol., 348, 2005
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3VUB
 | | CCDB, A TOPOISOMERASE POISON FROM E. COLI | | 分子名称: | CCDB, CHLORIDE ION | | 著者 | Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L. | | 登録日 | 1998-04-17 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
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4PP7
 | | Highly Potent and Selective 3-N-methylquinazoline-4(3H)-one Based Inhibitors of B-RafV600E Kinase | | 分子名称: | N-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide, Serine/threonine-protein kinase B-raf | | 著者 | Wenglowsky, S, Ren, L, Grina, J, Hansen, J.D, Laird, E.R, Moreno, D, Dinkel, V, Gloor, S.L, Hastings, G, Rana, S, Rasor, K, Sturgis, H.L, Voegtli, W.C, Vigers, G.P.A, Willis, B, Mathieu, S, Rudolph, J. | | 登録日 | 2014-02-26 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.
Bioorg.Med.Chem.Lett., 24, 2014
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4VUB
 | | CCDB, A TOPOISOMERASE POISON FROM ESCHERICHIA COLI | | 分子名称: | CCDB, CHLORIDE ION | | 著者 | Loris, R, Dao-Thi, M.-H, Bahasi, E.M, Van Melderen, L, Poortmans, F, Liddington, R, Couturier, M, Wyns, L. | | 登録日 | 1998-04-17 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structure of CcdB, a topoisomerase poison from E. coli.
J.Mol.Biol., 285, 1999
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3OLG
 | | Structures of human pancreatic alpha-amylase in complex with acarviostatin III03 | | 分子名称: | (1S,2S,3R,6R)-6-amino-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Qin, X, Ren, L. | | 登録日 | 2010-08-26 | | 公開日 | 2011-04-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of human pancreatic alpha-amylase in complex with acarviostatins: Implications for drug design against type II diabetes.
J.Struct.Biol., 174, 2011
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