5MIV

G307E variant of murine Apoptosis Inducing Factor in complex with NAD+

Summary for 5MIV

Entry DOI	10.2210/pdb5miv/pdb
Related	5MIU
Descriptor	Apoptosis-inducing factor 1, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	oxidoreductase, apoptosis inducing factor
Biological source	Mus musculus (House mouse)
Cellular location	Mitochondrion intermembrane space : Q9Z0X1
Total number of polymer chains	2
Total formula weight	119698.48
Authors	Sorrentino, L.,Cossu, F.,Aliverti, A.,Milani, M.,Mastrangelo, E. (deposition date: 2016-11-29, release date: 2017-07-12, Last modification date: 2024-01-17)
Primary citation	Sorrentino, L.,Cossu, F.,Milani, M.,Aliverti, A.,Mastrangelo, E. Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor. Biochem. Biophys. Res. Commun., 490:1011-1017, 2017 Cited by PubMed: 28666871 DOI: 10.1016/j.bbrc.2017.06.156 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation