5MIV
G307E variant of murine Apoptosis Inducing Factor in complex with NAD+
Summary for 5MIV
Entry DOI | 10.2210/pdb5miv/pdb |
Related | 5MIU |
Descriptor | Apoptosis-inducing factor 1, mitochondrial, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | oxidoreductase, apoptosis inducing factor |
Biological source | Mus musculus (House mouse) |
Cellular location | Mitochondrion intermembrane space : Q9Z0X1 |
Total number of polymer chains | 2 |
Total formula weight | 119698.48 |
Authors | Sorrentino, L.,Cossu, F.,Aliverti, A.,Milani, M.,Mastrangelo, E. (deposition date: 2016-11-29, release date: 2017-07-12, Last modification date: 2024-01-17) |
Primary citation | Sorrentino, L.,Cossu, F.,Milani, M.,Aliverti, A.,Mastrangelo, E. Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor. Biochem. Biophys. Res. Commun., 490:1011-1017, 2017 Cited by PubMed: 28666871DOI: 10.1016/j.bbrc.2017.06.156 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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