1R8M

SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS

Summary for 1R8M

Entry DOI	10.2210/pdb1r8m/pdb
Related	1BC9 1KU1 1PBV 1R8Q 1R8R 1R8S
Descriptor	Arno, MANGANESE (II) ION, FORMIC ACID, ... (4 entities in total)
Functional Keywords	exchange factor
Biological source	Homo sapiens (human)
Cellular location	Cell membrane ; Peripheral membrane protein : Q99418
Total number of polymer chains	1
Total formula weight	23615.72
Authors	Renault, L.,Guibert, B.,Cherfils, J. (deposition date: 2003-10-27, release date: 2004-01-20, Last modification date: 2023-08-23)
Primary citation	Renault, L.,Guibert, B.,Cherfils, J. Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor Nature, 426:525-530, 2003 Cited by PubMed: 14654833 DOI: 10.1038/nature02197 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation