1R8M
SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Arno | polymer | 203 | 23514.8 | 1 | UniProt (Q99418) Pfam (PF01369) | Homo sapiens (human) | ARF nucleotide-binding site opener, cytohesin 2, ARF exchange factor |
| 2 | B (E) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (E) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | D (E) | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence modifications
E: 50 - 252 (UniProt: Q99418)
| PDB | External Database | Details |
|---|---|---|
| Cme 174 | Cys 174 | modified residue |
| Tyr 190 | Phe 190 | engineered mutation |
| Ser 191 | Ala 191 | engineered mutation |
| Asp 198 | Ser 198 | engineered mutation |
| Met 208 | Pro 208 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23514.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 101.0 | |
| All* | Total formula weight | 23615.7 |
