1R8M

SEC7 DOMAIN OF THE ARF EXCHANGE FACTOR ARNO WITH BREFELDIN A-SENSITIZING MUTATIONS

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005085	molecular_function	guanyl-nucleotide exchange factor activity
E	0032012	biological_process	regulation of ARF protein signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN E 253

Chain	Residue
E	HIS127
E	ASP131
E	ASN240
E	HOH266
E	HOH360
E	HOH365

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT E 254

Chain	Residue
E	ILE245
E	ILE193
E	ASN196
E	THR197

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