8B9F
| Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion | 分子名称: | Complement decay-accelerating factor, Genome polyprotein, SPHINGOSINE | 著者 | Stuart, D.I, Ren, J, Qin, L, Zhou, D. | 登録日 | 2022-10-05 | 公開日 | 2022-12-07 | 最終更新日 | 2023-01-04 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Switching of Receptor Binding Poses between Closely Related Enteroviruses. Viruses, 14, 2022
|
|
8B8R
| Complex of Echovirus 11 with its attaching receptor decay-accelerating factor (CD55) | 分子名称: | DECAY ACCELERATING FACTOR (CD55), SPHINGOSINE, VP1, ... | 著者 | Stuart, D.I, Ren, J, Zhou, D, Qin, L. | 登録日 | 2022-10-04 | 公開日 | 2022-12-07 | 最終更新日 | 2023-01-04 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Switching of Receptor Binding Poses between Closely Related Enteroviruses. Viruses, 14, 2022
|
|
3DIF
| |
3ME4
| Crystal structure of mouse RANK | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Walter, S.W, Liu, C, Zhu, X, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J. | 登録日 | 2010-03-31 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Structural and Functional Insights of RANKL-RANK Interaction and Signaling. J.Immunol., 2010
|
|
4R3M
| Crystal structure of Human Hsp90 with JR9 | 分子名称: | Heat shock protein HSP 90-alpha, N~3~-benzyl-2-[(6-bromo-1,3-benzodioxol-5-yl)methyl]imidazo[1,2-a]pyrazine-3,8-diamine | 著者 | Li, J, Yang, M, Ren, J, Xiong, B, He, J. | 登録日 | 2014-08-16 | 公開日 | 2014-11-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienayme reaction and their Hsp90 inhibitory activity. Org.Biomol.Chem., 13, 2015
|
|
1U8A
| Crystal Structure of Mycobacterium Tuberculosis Shikimate Kinase in Complex with Shikimate and ADP at 2.15 Angstrom Resolution | 分子名称: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | 著者 | Dhaliwal, B, Nichols, C.E, Ren, J, Lockyer, M, Charles, I, Hawkins, A.R, Stammers, D.K. | 登録日 | 2004-08-05 | 公開日 | 2004-10-19 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystallographic studies of shikimate binding and induced conformational changes in Mycobacterium tuberculosis shikimate kinase. Febs Lett., 574, 2004
|
|
3HHF
| Structure of CrgA regulatory domain, a LysR-type transcriptional regulator from Neisseria meningitidis. | 分子名称: | CHLORIDE ION, Transcriptional regulator, LysR family | 著者 | Sainsbury, S, Ren, J, Owens, R.J, Stuart, D.I, Oxford Protein Production Facility (OPPF) | 登録日 | 2009-05-15 | 公開日 | 2009-07-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators Nucleic Acids Res., 37, 2009
|
|
3HHG
| Structure of CrgA, a LysR-type transcriptional regulator from Neisseria meningitidis. | 分子名称: | Transcriptional regulator, LysR family | 著者 | Sainsbury, S, Ren, J, Owens, R.J, Stuart, D.I, Oxford Protein Production Facility (OPPF) | 登録日 | 2009-05-15 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators Nucleic Acids Res., 37, 2009
|
|
6A5Q
| |
3G3Z
| The structure of NMB1585, a MarR family regulator from Neisseria meningitidis | 分子名称: | Transcriptional regulator, MarR family | 著者 | Nichols, C.E, Sainsbury, S, Ren, J, Walter, T.S, Verma, A, Stammers, D.K, Saunders, N.J, Owens, R.J, Oxford Protein Production Facility (OPPF) | 登録日 | 2009-02-03 | 公開日 | 2009-04-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of NMB1585, a MarR-family regulator from Neisseria meningitidis Acta Crystallogr.,Sect.F, 65, 2009
|
|
6A5S
| Structure of 14-3-3 gamma in complex with TFEB 14-3-3 binding motif | 分子名称: | 14-3-3 protein gamma, MAGNESIUM ION, SODIUM ION, ... | 著者 | Xu, Y, Ren, J.Q, Feng, W. | 登録日 | 2018-06-25 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization. Autophagy, 15, 2019
|
|
3ME2
| Crystal structure of mouse RANKL-RANK complex | 分子名称: | CHLORIDE ION, SODIUM ION, Tumor necrosis factor ligand superfamily member 11, ... | 著者 | Walter, S.W, Liu, C.Z, Zhu, X.K, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J. | 登録日 | 2010-03-31 | 公開日 | 2010-06-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and Functional Insights of RANKL-RANK Interaction and Signaling. J.Immunol., 2010
|
|
8CII
| Delta-RBD complex with BA.2-07 fab, SARS1-34 fab and C1 nanobody | 分子名称: | BA.2-07 fab Heavy Chain, BA.2-07 fab Light Chain, C1 nanobody, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I, Fry, E.E. | 登録日 | 2023-02-09 | 公開日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Potent cross-reactive mAbs from BA.4/5 breakthrough infection To Be Published
|
|
5JQ3
| Crystal structure of Ebola glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, Envelope glycoprotein 2, ... | 著者 | Zhao, Y, Ren, J, Stuart, D.I. | 登録日 | 2016-05-04 | 公開日 | 2016-06-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature, 535, 2016
|
|
5JQB
| Crystal structure of Ebola glycoprotein in complex with ibuprofen | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, Envelope glycoprotein 2, ... | 著者 | Zhao, Y, Ren, J, Stuart, D.I. | 登録日 | 2016-05-04 | 公開日 | 2016-06-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature, 535, 2016
|
|
6T4C
| Bovine enterovirus F3 in complex with glutathione | 分子名称: | GLUTATHIONE, GLYCEROL, POTASSIUM ION, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Walter, T.S, Fry, E.E, Stuart, D.I. | 登録日 | 2019-10-13 | 公開日 | 2020-01-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Glutathione facilitates enterovirus assembly by binding at a druggable pocket. Commun Biol, 3, 2020
|
|
5JQ7
| Crystal structure of Ebola glycoprotein in complex with toremifene | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, ... | 著者 | Zhao, Y, Ren, J, Stuart, D.I. | 登録日 | 2016-05-04 | 公開日 | 2016-06-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature, 535, 2016
|
|
6T40
| Bovine enterovirus F3 in complex with a Cysteinylglycine dipeptide | 分子名称: | CHLORIDE ION, CYSTEINE, GLYCEROL, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Walter, T.S, Fry, E.E, Stuart, D.I. | 登録日 | 2019-10-11 | 公開日 | 2020-08-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Glutathione facilitates enterovirus assembly by binding at a druggable pocket. Commun Biol, 3, 2020
|
|
6T48
| Bovine enterovirus F3 in complex with glutathione and a Cysteinylglycine dipeptide | 分子名称: | CHLORIDE ION, CYSTEINE, GLUTATHIONE, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Walter, T.S, Fry, E.E, Stuart, D.I. | 登録日 | 2019-10-12 | 公開日 | 2020-01-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Glutathione facilitates enterovirus assembly by binding at a druggable pocket. Commun Biol, 3, 2020
|
|
3DOK
| Crystal structure of K103N mutant HIV-1 reverse transcriptase in complex with GW678248. | 分子名称: | 2-{4-chloro-2-[(3-chloro-5-cyanophenyl)carbonyl]phenoxy}-N-(2-methyl-4-sulfamoylphenyl)acetamide, PHOSPHATE ION, Reverse transcriptase/ribonuclease H, ... | 著者 | Chamberlain, P.P, Ren, J, Stammers, D.K. | 登録日 | 2008-07-04 | 公開日 | 2008-08-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. J.Med.Chem., 51, 2008
|
|
2CCG
| Crystal structure of His-tagged S. aureus thymidylate kinase complexed with thymidine monophosphate (TMP) | 分子名称: | THYMIDINE-5'-PHOSPHATE, THYMIDYLATE KINASE | 著者 | Kotaka, M, Dhaliwal, B, Ren, J, Nichols, C.E, Angell, R, Lockyer, M, Hawkins, A.R, Stammers, D.K. | 登録日 | 2006-01-16 | 公開日 | 2006-03-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of S. Aureus Thymidylate Kinase Reveal an Atypical Active Site Configuration and an Intermediate Conformational State Upon Substrate Binding Protein Sci., 15, 2006
|
|
3DOL
| Crystal structure of L100I mutant HIV-1 reverse transcriptase in complex with GW695634. | 分子名称: | N-({4-[({4-chloro-2-[(3-chloro-5-cyanophenyl)carbonyl]phenoxy}acetyl)amino]-3-methylphenyl}sulfonyl)propanamide, PHOSPHATE ION, Reverse transcriptase/ribonuclease H, ... | 著者 | Chamberlain, P.P, Ren, J, Stammers, D.K. | 登録日 | 2008-07-04 | 公開日 | 2008-08-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. J.Med.Chem., 51, 2008
|
|
2Q5I
| Crystal structure of apo S581L Glycyl-tRNA synthetase mutant | 分子名称: | Glycyl-tRNA synthetase, SULFATE ION | 著者 | Cader, M.Z, Ren, J, James, P.A, Bird, L.E, Talbot, K, Stammers, D.K, Oxford Protein Production Facility (OPPF) | 登録日 | 2007-06-01 | 公開日 | 2007-06-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy. Febs Lett., 581, 2007
|
|
5ABJ
| Structure of Coxsackievirus A16 in complex with GPP3 | 分子名称: | 1-[(3S)-5-[4-[(E)-ETHOXYIMINOMETHYL]PHENOXY]-3-METHYL-PENTYL]-3-PYRIDIN-4-YL-IMIDAZOLIDIN-2-ONE, CHLORIDE ION, SODIUM ION, ... | 著者 | De Colibus, L, Wang, X, Tijsma, A, Neyts, J, Spyrou, J.A.B, Ren, J, Grimes, J.M, Puerstinger, G, Leyssen, P, Fry, E.E, Rao, Z, Stuart, D.I. | 登録日 | 2015-08-06 | 公開日 | 2015-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure Elucidation of Coxsackievirus A16 in Complex with Gpp3 Informs a Systematic Review of Highly Potent Capsid Binders to Enteroviruses. Plos Pathog., 11, 2015
|
|
2Q5H
| Crystal structure of apo-wildtype Glycyl-tRNA synthetase | 分子名称: | Glycyl-tRNA synthetase | 著者 | Cader, M.Z, Ren, J, James, P.A, Bird, L.E, Talbot, K, Stammers, D.K, Oxford Protein Production Facility (OPPF) | 登録日 | 2007-06-01 | 公開日 | 2007-06-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy. Febs Lett., 581, 2007
|
|