2CCG
Crystal structure of His-tagged S. aureus thymidylate kinase complexed with thymidine monophosphate (TMP)
Summary for 2CCG
| Entry DOI | 10.2210/pdb2ccg/pdb |
| Related | 2CCJ 2CCK |
| Descriptor | THYMIDYLATE KINASE, THYMIDINE-5'-PHOSPHATE (3 entities in total) |
| Functional Keywords | kinase, transferase, nucleotide biosynthesis, tmp-binding, atp-binding |
| Biological source | STAPHYLOCOCCUS AUREUS |
| Total number of polymer chains | 2 |
| Total formula weight | 51896.33 |
| Authors | Kotaka, M.,Dhaliwal, B.,Ren, J.,Nichols, C.E.,Angell, R.,Lockyer, M.,Hawkins, A.R.,Stammers, D.K. (deposition date: 2006-01-16, release date: 2006-03-08, Last modification date: 2023-12-13) |
| Primary citation | Kotaka, M.,Dhaliwal, B.,Ren, J.,Nichols, C.E.,Angell, R.,Lockyer, M.,Hawkins, A.R.,Stammers, D.K. Structures of S. Aureus Thymidylate Kinase Reveal an Atypical Active Site Configuration and an Intermediate Conformational State Upon Substrate Binding Protein Sci., 15:774-, 2006 Cited by PubMed: 16522804DOI: 10.1110/PS.052002406 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report
