2CCJ

Crystal structure of S. aureus thymidylate kinase complexed with thymidine monophosphate

Summary for 2CCJ

Entry DOI	10.2210/pdb2ccj/pdb
Related	2CCG 2CCK
Descriptor	THYMIDYLATE KINASE, CHLORIDE ION, THYMIDINE-5'-PHOSPHATE, ... (5 entities in total)
Functional Keywords	kinase, transferase, nucleotide biosynthesis, tmp-binding, atp-binding, thymidylate kinase
Biological source	STAPHYLOCOCCUS AUREUS
Total number of polymer chains	2
Total formula weight	48239.26
Authors	Kotaka, M.,Dhaliwal, B.,Ren, J.,Nichols, C.E.,Angell, R.,Lockyer, M.,Hawkins, A.R.,Stammers, D.K. (deposition date: 2006-01-16, release date: 2006-03-08, Last modification date: 2023-12-13)
Primary citation	Kotaka, M.,Dhaliwal, B.,Ren, J.,Nichols, C.E.,Angell, R.,Lockyer, M.,Hawkins, A.R.,Stammers, D.K. Structures of S. Aureus Thymidylate Kinase Reveal an Atypical Active Site Configuration and an Intermediate Conformational State Upon Substrate Binding Protein Sci., 15:774-, 2006 Cited by PubMed: 16522804 DOI: 10.1110/PS.052002406 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation