5DDO
 
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5K7C
 | | The native structure of native pistol ribozyme | | Descriptor: | DNA/RNA 11-MER, MAGNESIUM ION, RNA 47-MER | | Authors: | Ren, A, Patel, D. | | Deposit date: | 2016-05-26 | | Release date: | 2016-07-13 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
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5K7D
 | | The structure of native pistol ribozyme, bound to Iridium | | Descriptor: | DNA/RNA 11-MER, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ... | | Authors: | Ren, A, Patel, D. | | Deposit date: | 2016-05-26 | | Release date: | 2016-07-13 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
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4RGF
 | | Crystal structure of the in-line aligned env22 twister ribozyme soaked with Mn2+ | | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | | Authors: | Ren, A, Rajashankar, K.R, Simanshu, D, Patel, D. | | Deposit date: | 2014-09-30 | | Release date: | 2014-12-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2008 Å) | | Cite: | In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
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4RGE
 | | Crystal structure of the in-line aligned env22 twister ribozyme | | Descriptor: | MAGNESIUM ION, env22 twister ribozyme | | Authors: | Ren, A, Rajashankar, K.R, Simanshu, D, Patel, D. | | Deposit date: | 2014-09-30 | | Release date: | 2014-12-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme.
Nat Commun, 5, 2014
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6LAU
 | | the wildtype SAM-VI riboswitch bound to SAH | | Descriptor: | CESIUM ION, GUANOSINE-5'-TRIPHOSPHATE, RNA (54-MER), ... | | Authors: | Ren, A, Sun, A. | | Deposit date: | 2019-11-13 | | Release date: | 2020-01-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.109 Å) | | Cite: | SAM-VI riboswitch structure and signature for ligand discrimination.
Nat Commun, 10, 2019
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6LAZ
 | | the wildtype SAM-VI riboswitch bound to a N-mustard SAM analog M1 | | Descriptor: | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(2-hydroxyethyl)amino]-2-azaniumyl-butanoate, MAGNESIUM ION, RNA (55-MER), ... | | Authors: | Ren, A, Sun, A. | | Deposit date: | 2019-11-13 | | Release date: | 2020-01-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | SAM-VI riboswitch structure and signature for ligand discrimination.
Nat Commun, 10, 2019
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6LAS
 | | the wildtype SAM-VI riboswitch bound to SAM | | Descriptor: | RNA (55-MER), S-ADENOSYLMETHIONINE, U1 small nuclear ribonucleoprotein A | | Authors: | Ren, A, Sun, A. | | Deposit date: | 2019-11-13 | | Release date: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.708 Å) | | Cite: | SAM-VI riboswitch structure and signature for ligand discrimination.
Nat Commun, 10, 2019
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4X0G
 | | Structure of Bsg25A binding with DNA | | Descriptor: | ACETATE ION, Blastoderm-specific gene 25A, DNA (5'-D(*GP*TP*TP*CP*CP*AP*AP*TP*TP*GP*GP*AP*A)-3') | | Authors: | Ren, A. | | Deposit date: | 2014-11-21 | | Release date: | 2015-01-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.2065 Å) | | Cite: | Common and distinct DNA-binding and regulatory activities of the BEN-solo transcription factor family.
Genes Dev., 29, 2015
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5K7E
 | | The structure of pistol ribozyme, soaked with Mn2+ | | Descriptor: | DNA/RNA 11-MER, MANGANESE (II) ION, RNA 47-MER | | Authors: | Ren, A, Patel, D. | | Deposit date: | 2016-05-26 | | Release date: | 2016-07-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.27 Å) | | Cite: | Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.
Nat.Chem.Biol., 12, 2016
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6JQ6
 | | Hatchet Ribozyme Structure soaking with Ir(NH3)6+ | | Descriptor: | IRIDIUM HEXAMMINE ION, RNA (81-MER) | | Authors: | Ren, A, Zheng, L. | | Deposit date: | 2019-03-29 | | Release date: | 2019-06-12 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.626 Å) | | Cite: | Hatchet ribozyme structure and implications for cleavage mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6JQ5
 | | The structure of Hatchet Ribozyme | | Descriptor: | MAGNESIUM ION, RNA (82-MER) | | Authors: | Ren, A, Zheng, L. | | Deposit date: | 2019-03-29 | | Release date: | 2019-06-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.059 Å) | | Cite: | Hatchet ribozyme structure and implications for cleavage mechanism.
Proc.Natl.Acad.Sci.USA, 116, 2019
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5DDP
 | | L-glutamine riboswitch bound with L-glutamine | | Descriptor: | GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ... | | Authors: | Ren, A, Patel, D.J. | | Deposit date: | 2015-08-25 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
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5DDQ
 | | L-glutamine riboswitch bound with L-glutamine soaked with Mn2+ | | Descriptor: | GLUTAMINE, L-glutamine riboswitch RNA (61-MER), MAGNESIUM ION, ... | | Authors: | Ren, A, Patel, D.J. | | Deposit date: | 2015-08-25 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
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5DDR
 | | L-glutamine riboswitch bound with L-glutamine soaked with Cs+ | | Descriptor: | CESIUM ION, GLUTAMINE, L-glutamine riboswitch RNA (61-MER), ... | | Authors: | Ren, A, Patel, D.J. | | Deposit date: | 2015-08-25 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.605 Å) | | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
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5KAV
 | | The structure of SAV2435 | | Descriptor: | GLYCEROL, SA2223 protein | | Authors: | Moreno, A, Wade, H. | | Deposit date: | 2016-06-02 | | Release date: | 2016-08-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
Biochemistry, 55, 2016
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5KAT
 | | The structure of SAV2435 bound to TETRAPHENYLPHOSPHONIUM | | Descriptor: | GLYCEROL, SA2223 protein, TETRAPHENYLPHOSPHONIUM | | Authors: | Moreno, A, Wade, H. | | Deposit date: | 2016-06-02 | | Release date: | 2016-08-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
Biochemistry, 55, 2016
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5KCB
 | | The structure of SAV2435 bound to ethidium bromide | | Descriptor: | ETHIDIUM, SA2223 protein, SULFATE ION | | Authors: | Moreno, A, Wade, H. | | Deposit date: | 2016-06-06 | | Release date: | 2016-08-24 | | Last modified: | 2019-11-27 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
Biochemistry, 55, 2016
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4IX7
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4ZNP
 | | The structure of A pfI Riboswitch Bound to ZMP | | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, pfI Riboswitch | | Authors: | Ren, A, Patel, D.J, Rajashankar, R.K. | | Deposit date: | 2015-05-05 | | Release date: | 2015-08-26 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism.
Structure, 23, 2015
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5DUN
 | | The crystal structure of OMe substituted twister ribozyme | | Descriptor: | MAGNESIUM ION, POTASSIUM ION, RNA (54-MER) | | Authors: | Ren, A, Patel, D.J, Micura, R, Rajashankar, K.R. | | Deposit date: | 2015-09-19 | | Release date: | 2015-10-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.
Angew.Chem.Int.Ed.Engl., 54, 2015
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5KAX
 | | The structure of CTR107 protein bound to RHODAMINE 6G | | Descriptor: | CTR107 protein, GLYCEROL, RHODAMINE 6G | | Authors: | Moreno, A, Wade, H. | | Deposit date: | 2016-06-02 | | Release date: | 2016-08-24 | | Last modified: | 2019-11-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
Biochemistry, 55, 2016
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5KAU
 | | The structure of SAV2435 bound to RHODAMINE 6G | | Descriptor: | GLYCEROL, RHODAMINE 6G, SA2223 protein | | Authors: | Moreno, A, Wade, H. | | Deposit date: | 2016-06-02 | | Release date: | 2016-08-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
Biochemistry, 55, 2016
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5KAW
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4O9H
 | | Structure of Interleukin-6 in complex with a Camelid Fab fragment | | Descriptor: | Heavy Chain of the Camelid Fab fragment 61H7, Interleukin-6, Light Chain of the Camelid Fab fragment 61H7 | | Authors: | Klarenbeek, A, Blanchetot, C, Schragel, G, Sadi, A.S, Ongenae, N, Hemrika, W, Wijdenes, J, Spinelli, S, Desmyter, A, Cambillau, C, Hultberg, A, Kretz-rommel, A, Dreier, T, De haard, H.J.W, Roovers, R.C. | | Deposit date: | 2014-01-02 | | Release date: | 2015-04-15 | | Last modified: | 2015-04-29 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Combining residues of naturally-occurring Camelid somatic affinity variants yields ultra-potent human therapeutic IL-6 antibodies
To be Published
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