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PDB: 94 件
6I7G
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BU of 6i7g by Molmil
Crystal structure of dimeric wild type FICD complexed with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, DI(HYDROXYETHYL)ETHER, ...
著者Perera, L.A, Yan, Y, Read, R.J, Ron, D.
登録日2018-11-16
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6I7L
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BU of 6i7l by Molmil
Crystal structure of monomeric FICD mutant L258D complexed with MgAMP-PNP
分子名称: Adenosine monophosphate-protein transferase FICD, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Perera, L.A, Yan, Y, Read, R.J, Ron, D.
登録日2018-11-16
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6I7K
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BU of 6i7k by Molmil
Crystal structure of monomeric FICD mutant L258D complexed with MgATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, ETHANOL, ...
著者Perera, L.A, Yan, Y, Read, R.J, Ron, D.
登録日2018-11-16
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6I7J
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BU of 6i7j by Molmil
Crystal structure of monomeric FICD mutant L258D
分子名称: Adenosine monophosphate-protein transferase FICD, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ...
著者Perera, L.A, Yan, Y, Read, R.J, Ron, D.
登録日2018-11-16
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6I3I
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BU of 6i3i by Molmil
Crystal structure of reactive center loop (RCL) cleaved angiotensinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen
著者Yan, Y, Read, R.J.
登録日2018-11-06
公開日2018-12-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
6I3F
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BU of 6i3f by Molmil
Crystal structure of the complex of human angiotensinogen and renin at 2.55 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensinogen, ...
著者Yan, Y, Read, R.J.
登録日2018-11-06
公開日2018-12-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
6I7I
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BU of 6i7i by Molmil
Crystal structure of dimeric FICD mutant K256A complexed with MgATP
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ADENOSINE-5'-TRIPHOSPHATE, Adenosine monophosphate-protein transferase FICD, ...
著者Perera, L.A, Yan, Y, Read, R.J, Ron, D.
登録日2018-11-16
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
6HUF
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BU of 6huf by Molmil
Coping with strong translational non-crystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Rab-27A
著者Jamshidiha, M, Perez-Dorado, I, Murray, J.W, Tate, E.W, Cota, E, Read, R.J.
登録日2018-10-08
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Coping with strong translational noncrystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a.
Acta Crystallogr D Struct Biol, 75, 2019
6I7H
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BU of 6i7h by Molmil
Crystal structure of dimeric FICD mutant K256S
分子名称: Adenosine monophosphate-protein transferase FICD, MAGNESIUM ION
著者Perera, L.A, Yan, Y, Read, R.J, Ron, D.
登録日2018-11-16
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Embo J., 38, 2019
4Z9G
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BU of 4z9g by Molmil
Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395 in a hexagonal setting with translational non-crystallographic symmetry
分子名称: 3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine, Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1, OLEIC ACID, ...
著者Dore, A.S, Bortolato, A, Hollenstein, K, Cheng, R.K.Y, Read, R.J, Marshall, F.H.
登録日2015-04-10
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.183 Å)
主引用文献Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures.
Curr Mol Pharmacol, 10, 2017
4UFI
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BU of 4ufi by Molmil
Mouse Galactocerebrosidase complexed with aza-galacto-fagomine AGF
分子名称: (3R,4S,5R)-3-(hydroxymethyl)-1,2-diazinane-4,5-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
登録日2015-03-17
公開日2015-03-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFL
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BU of 4ufl by Molmil
Mouse Galactocerebrosidase complexed with deoxy-galacto-noeurostegine DGN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
登録日2015-03-17
公開日2015-03-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFJ
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BU of 4ufj by Molmil
Mouse Galactocerebrosidase complexed with iso-galacto-fagomine lactam IGL
分子名称: (3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
登録日2015-03-17
公開日2015-03-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFM
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BU of 4ufm by Molmil
Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ
分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
登録日2015-03-17
公開日2015-04-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UEX
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BU of 4uex by Molmil
Structure of human Saposin A at lysosomal pH
分子名称: PROSAPOSIN
著者Hill, C.H, Read, R.J, Deane, J.E.
登録日2014-12-20
公開日2015-07-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Human Saposin a at Lysosomal Ph.
Acta Crystallogr.,Sect.D, 71, 2015
4UFK
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BU of 4ufk by Molmil
Mouse Galactocerebrosidase complexed with dideoxy-imino-lyxitol DIL
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
登録日2015-03-17
公開日2015-03-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
4UFH
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BU of 4ufh by Molmil
Mouse Galactocerebrosidase complexed with iso-galacto-fagomine IGF
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E.
登録日2015-03-17
公開日2015-03-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
1PTO
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BU of 1pto by Molmil
THE STRUCTURE OF A PERTUSSIS TOXIN-SUGAR COMPLEX AS A MODEL FOR RECEPTOR BINDING
分子名称: N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, PERTUSSIS TOXIN, PERTUSSIS TOXIN (SUBUNIT S1), ...
著者Stein, P.E, Read, R.J.
登録日1994-03-22
公開日1995-09-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of a pertussis toxin-sugar complex as a model for receptor binding.
Nat.Struct.Biol., 1, 1994
5FQL
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BU of 5fql by Molmil
Insights into Hunter syndrome from the structure of iduronate-2- sulfatase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Demydchuk, M, Hill, C.H, Zhou, A, Bunkoczi, G, Stein, P.E, Marchesan, D, Deane, J.E, Read, R.J.
登録日2015-12-11
公開日2017-01-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into Hunter syndrome from the structure of iduronate-2-sulfatase.
Nat Commun, 8, 2017
6RPX
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BU of 6rpx by Molmil
Cytokine receptor-like factor 3 C-terminus residues 174-442: native
分子名称: Cytokine receptor-like factor 3
著者Mifsud, R.W, Yan, Y, Bennett, C, Read, R.J.
登録日2019-05-15
公開日2020-03-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Blood, 139, 2022
6RPZ
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BU of 6rpz by Molmil
Cytokine receptor-like factor 3 C-terminus residues 174-442: native collected with 1.7A wavelength
分子名称: Cytokine receptor-like factor 3
著者Mifsud, R.W, Yan, Y, Bennett, C, Read, R.J.
登録日2019-05-15
公開日2020-03-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Blood, 139, 2022
6RPY
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BU of 6rpy by Molmil
Cytokine receptor-like factor 3 C-terminus residues 174-442: Hg-SAD derivative
分子名称: Cytokine receptor-like factor 3, MERCURY (II) ION
著者Mifsud, R.W, Yan, Y, Bennett, C, Read, R.J.
登録日2019-05-15
公開日2020-03-25
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Blood, 139, 2022
5HK5
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BU of 5hk5 by Molmil
Structure of the Grem2-GDF5 Inhibitory Complex
分子名称: Gremlin-2, Growth/differentiation factor 5
著者Nolan, K, Thompson, T.B, Read, R.J.
登録日2016-01-13
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism.
Cell Rep, 16, 2016
8AXG
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BU of 8axg by Molmil
Crystal structure of Fusobacterium nucleatum fusolisin protease
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fusolisin, ...
著者Isupov, M.N, Wiener, R, Rouvinski, A, Fahoum, J, Kumar, M, Read, R.J.
登録日2022-08-31
公開日2023-09-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of Fusobacterium nucleatum fusolisin protease
To Be Published
2C5C
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BU of 2c5c by Molmil
Shiga-like toxin 1 B subunit complexed with a bivalent inhibitor
分子名称: DIETHYL PROPANE-1,3-DIYLBISCARBAMATE, SHIGA-LIKE TOXIN 1 B SUBUNIT, SULFATE ION, ...
著者Dodd, R.B, Read, R.J.
登録日2005-10-26
公開日2006-11-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Extensive Cross-Linking of the Shiga-Like Toxin 1 B Subunit by a Bivalent Ligand
To be Published

226707

件を2024-10-30に公開中

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