6I7L

Crystal structure of monomeric FICD mutant L258D complexed with MgAMP-PNP

Summary for 6I7L

Entry DOI	10.2210/pdb6i7l/pdb
Descriptor	Adenosine monophosphate-protein transferase FICD, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	fic, ampylation, upr, bip, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	39981.55
Authors	Perera, L.A.,Yan, Y.,Read, R.J.,Ron, D. (deposition date: 2018-11-16, release date: 2019-09-25, Last modification date: 2024-01-24)
Primary citation	Perera, L.A.,Rato, C.,Yan, Y.,Neidhardt, L.,McLaughlin, S.H.,Read, R.J.,Preissler, S.,Ron, D. An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP. Embo J., 38:e102177-e102177, 2019 Cited by PubMed: 31531998 DOI: 10.15252/embj.2019102177 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation