6RPZ

Cytokine receptor-like factor 3 C-terminus residues 174-442: native collected with 1.7A wavelength

Summary for 6RPZ

Entry DOI	10.2210/pdb6rpz/pdb
Related	6RPX
Descriptor	Cytokine receptor-like factor 3 (2 entities in total)
Functional Keywords	platelet development, fibronectin domain, spry domain, blood clotting
Biological source	Mus musculus (Mouse)
Total number of polymer chains	1
Total formula weight	30057.35
Authors	Mifsud, R.W.,Yan, Y.,Bennett, C.,Read, R.J. (deposition date: 2019-05-15, release date: 2020-03-25, Last modification date: 2024-01-31)
Primary citation	Bennett, C.,Lawrence, M.,Guerrero, J.A.,Stritt, S.,Waller, A.K.,Yan, Y.,Mifsud, R.W.,Ballester-Beltran, J.,Baig, A.,Mueller, A.,Mayer, L.,Warland, J.,Penkett, C.J.,Akbari, P.,Moreau, T.,Evans, A.L.,Mookerjee, S.,Hoffman, G.J.,Saeb-Parsy, K.,Adams, D.J.,Couzens, A.L.,Bender, M.,Erber, W.N.,Nieswandt, B.,Read, R.J.,Ghevaert, C. CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia. Blood, 139:2227-2239, 2022 Cited by PubMed: 35051265 DOI: 10.1182/blood.2021013113 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation