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PDB: 100 results

5ZMC
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BU of 5zmc by Molmil
Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2
Descriptor: DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3'), Nuclear factor NF-kappa-B p100 subunit, ...
Authors:Xu, X, Bharath, S.R, Song, H.
Deposit date:2018-04-02
Release date:2018-09-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1.
Nat Commun, 9, 2018
5FHG
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BU of 5fhg by Molmil
Structure of unliganded Pif1 from Bacteroides sp
Descriptor: Uncharacterized protein
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FHD
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BU of 5fhd by Molmil
Structure of Bacteroides sp Pif1 complexed with tailed dsDNA resulting in ssDNA bound complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*CP*GP*GP*GP*GP*CP*CP*GP*CP*GP*C)-3'), MAGNESIUM ION, ...
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
4EIH
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BU of 4eih by Molmil
Crystal structure of Arg SH2 domain
Descriptor: Abelson tyrosine-protein kinase 2, CHLORIDE ION
Authors:Liu, W, MacGrath, S.M, Koleske, A.J, Boggon, T.J.
Deposit date:2012-04-05
Release date:2013-04-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Two Amino Acid Residues Confer Different Binding Affinities of Abelson Family Kinase Src Homology 2 Domains for Phosphorylated Cortactin.
J.Biol.Chem., 289, 2014
6YMY
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BU of 6ymy by Molmil
Cytochrome c oxidase from Saccharomyces cerevisiae
Descriptor: (2R,5S,11R,14R)-5,8,11-trihydroxy-2-(nonanoyloxy)-5,11-dioxido-16-oxo-14-[(propanoyloxy)methyl]-4,6,10,12,15-pentaoxa-5,11-diphosphanonadec-1-yl undecanoate, 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, COPPER (II) ION, ...
Authors:Berndtsson, J, Rathore, S, Ott, M.
Deposit date:2020-04-10
Release date:2020-09-09
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance.
Embo Rep., 21, 2020
3USU
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BU of 3usu by Molmil
Crystal structure of Butea monosperma seed lectin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Abhilash, J, Geethanandan, K, Bharath, S.R, Sadasivan, C, Haridas, M.
Deposit date:2011-11-24
Release date:2012-01-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Crystal structure of Butea monosperma seed lectin
To be Published
7UN5
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BU of 7un5 by Molmil
Structure of Type II Prion filaments from Gerstmann-Straussler-Scheinker disease
Descriptor: Major prion protein
Authors:Ozcan, K.A, Hoq, M.R, Bharath, S.R, Jiang, W.
Deposit date:2022-04-08
Release date:2022-07-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7UMQ
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BU of 7umq by Molmil
Structure of Type I Prion filaments from Gerstmann-Straussler-Scheinker disease
Descriptor: Major prion protein
Authors:Ozcan, K.A, Hoq, M.R, Bharath, S.R, Jiang, W.
Deposit date:2022-04-07
Release date:2022-07-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Cryo-EM structures of prion protein filaments from Gerstmann-Straussler-Scheinker disease.
Acta Neuropathol, 144, 2022
7TMC
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BU of 7tmc by Molmil
TMEM106B singlet filament extracted from MSTD neurodegenerative human brain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Transmembrane protein 106B
Authors:Hoq, M.R, Bharath, S.R, Jiang, W.
Deposit date:2022-01-19
Release date:2023-01-25
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Cross-beta helical filaments of Tau and TMEM106B in gray and white matter of multiple system tauopathy with presenile dementia.
Acta Neuropathol, 145, 2023
8SEL
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BU of 8sel by Molmil
Type IIIb beta-amyloid 40 Filaments from Down Syndrome
Descriptor: Amyloid-beta protein 40
Authors:Hoq, M.R, Vago, F.S, Bharath, S.R, Jiang, W.
Deposit date:2023-04-10
Release date:2024-04-03
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome.
Nat.Struct.Mol.Biol., 31, 2024
3ULR
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BU of 3ulr by Molmil
Lysozyme contamination facilitates crystallization of a hetero-trimericCortactin:Arg:Lysozyme complex
Descriptor: Abelson tyrosine-protein kinase 2, Lysozyme C, Src substrate cortactin
Authors:Liu, W, MacGrath, S, Koleske, A.J, Boggon, T.J.
Deposit date:2011-11-11
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Lysozyme contamination facilitates crystallization of a heterotrimeric cortactin-Arg-lysozyme complex.
Acta Crystallogr.,Sect.F, 68, 2012
6YMX
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BU of 6ymx by Molmil
CIII2/CIV respiratory supercomplex from Saccharomyces cerevisiae
Descriptor: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (1R)-2-(phosphonooxy)-1-[(tridecanoyloxy)methyl]ethyl pentadecanoate, (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(heptanoyloxy)methyl]ethyl octadecanoate, ...
Authors:Berndtsson, J, Rathore, S, Ott, M.
Deposit date:2020-04-10
Release date:2020-09-09
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Respiratory supercomplexes enhance electron transport by decreasing cytochrome c diffusion distance.
Embo Rep., 21, 2020
7X0E
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BU of 7x0e by Molmil
Structure of Pseudomonas NRPS protein, AmbB-TC in apo form
Descriptor: AMB antimetabolite synthase AmbB, N-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentakis(oxidanyl)hexyl]nonanamide
Authors:ChuYuanKee, M, Bharath, S.R, Song, H.
Deposit date:2022-02-22
Release date:2022-07-06
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into the substrate-bound condensation domains of non-ribosomal peptide synthetase AmbB.
Sci Rep, 12, 2022
6L3G
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BU of 6l3g by Molmil
Structural Basis for DNA Unwinding at Forked dsDNA by two coordinating Pif1 helicases
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*TP*TP*TP*T)-3'), ...
Authors:Su, N, Bharath, S.R, Song, H.
Deposit date:2019-10-10
Release date:2019-12-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for DNA unwinding at forked dsDNA by two coordinating Pif1 helicases.
Nat Commun, 10, 2019
9CZI
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BU of 9czi by Molmil
Paired helical tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor: Microtubule-associated protein tau
Authors:Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
Deposit date:2024-08-05
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZL
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BU of 9czl by Molmil
Straight tau filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor: Isoform Tau-C of Microtubule-associated protein tau
Authors:Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
Deposit date:2024-08-05
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
3OZZ
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BU of 3ozz by Molmil
Structure of a cytochrome b5 core-swap mutant
Descriptor: Cytochrome b5, PROTOPORPHYRIN IX CONTAINING FE
Authors:Terzyan, S, Parthasarathy, S, Zhang, X.C, Benson, D.
Deposit date:2010-09-27
Release date:2011-09-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a cytochrome b5 core-swap mutant
To be Published
7JG1
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BU of 7jg1 by Molmil
Dimeric Immunoglobin A (dIgA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ...
Authors:Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M.
Deposit date:2020-07-18
Release date:2020-11-11
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structures of Secretory and dimeric Immunoglobulin A.
Elife, 9, 2020
7JG2
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BU of 7jg2 by Molmil
Secretory Immunoglobin A (SIgA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ...
Authors:Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M.
Deposit date:2020-07-18
Release date:2020-11-11
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structures of Secretory and dimeric Immunoglobulin A.
Elife, 9, 2020
7X0F
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BU of 7x0f by Molmil
Structure of Pseudomonas NRPS protein, AmbB-TC bound to Ppant
Descriptor: 4'-PHOSPHOPANTETHEINE, AMB antimetabolite synthase AmbB
Authors:ChuYuanKee, M, Bharath, S.R, Song, H.
Deposit date:2022-02-22
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insights into the substrate-bound condensation domains of non-ribosomal peptide synthetase AmbB.
Sci Rep, 12, 2022
6LG2
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BU of 6lg2 by Molmil
VanR bound to Vanillate
Descriptor: 4-HYDROXY-3-METHOXYBENZOATE, Predicted transcriptional regulators
Authors:He, Y, Bharath, S.R, Song, H.
Deposit date:2019-12-04
Release date:2020-02-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Developing a highly efficient hydroxytyrosol whole-cell catalyst by de-bottlenecking rate-limiting steps.
Nat Commun, 11, 2020
9CZN
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BU of 9czn by Molmil
Type Ic amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor: Amyloid-beta protein 42
Authors:Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
Deposit date:2024-08-05
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
9CZP
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BU of 9czp by Molmil
Type Id amyloid-beta 42 filaments in dominantly inherited Alzheimer disease with cotton wool plaques
Descriptor: Amyloid-beta protein 42
Authors:Hoq, M.R, Vago, F.S, Ozcan, K.A, Bharath, S.R.
Deposit date:2024-08-05
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures of cotton wool plaques' amyloid beta and of tau filaments in dominantly inherited Alzheimer disease.
Acta Neuropathol, 148, 2024
2ZLF
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BU of 2zlf by Molmil
The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase
Descriptor: FTLDADF, Ribonucleoside-diphosphate reductase large chain 1
Authors:Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C.
Deposit date:2008-04-09
Release date:2008-08-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
4JF0
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BU of 4jf0 by Molmil
N79R mutant of N-acetylornithine aminotransferase
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ...
Authors:Bisht, S, Bharath, S.R, Murthy, M.R.N.
Deposit date:2013-02-27
Release date:2014-03-26
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases
To be Published

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