2CKH
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![BU of 2ckh by Molmil](/molmil-images/mine/2ckh) | SENP1-SUMO2 complex | Descriptor: | SENTRIN-SPECIFIC PROTEASE 1, SMALL UBIQUITIN-RELATED MODIFIER 2 | Authors: | Shen, L.N, Dong, C, Liu, H, Hay, R.T, Naismith, J.H. | Deposit date: | 2006-04-18 | Release date: | 2006-04-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Structure of Senp1-Sumo-2 Complex Suggests a Structural Basis for Discrimination between Sumo Paralogues During Processing. Biochem.J., 397, 2006
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2CME
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![BU of 2cme by Molmil](/molmil-images/mine/2cme) | The crystal structure of SARS coronavirus ORF-9b protein | Descriptor: | DECANE, HYPOTHETICAL PROTEIN 5 | Authors: | Meier, C, Aricescu, A.R, Assenberg, R, Aplin, R.T, Gilbert, R.J.C, Grimes, J.M, Stuart, D.I. | Deposit date: | 2006-05-06 | Release date: | 2006-07-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Crystal Structure of Orf-9B, a Lipid Binding Protein from the Sars Coronavirus. Structure, 14, 2006
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2YAC
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![BU of 2yac by Molmil](/molmil-images/mine/2yac) | Crystal structure of Polo-like kinase 1 in complex with NMS-P937 | Descriptor: | 1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO]-4,5-DIHYDROPYRIMIDO[5,4-G]INDAZOLE-3-CARBOXAMIDE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ... | Authors: | Bertrand, J.A, Bossi, R.T. | Deposit date: | 2011-02-18 | Release date: | 2011-04-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Nms-P937, a 4,5-Dihydro-1H-Pyrazolo[4,3-H]Quinazoline Derivative as Potent and Selective Polo-Like Kinase 1 Inhibitor. Bioorg.Med.Chem.Lett., 21, 2011
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2ALE
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![BU of 2ale by Molmil](/molmil-images/mine/2ale) | Crystal structure of yeast RNA splicing factor Snu13p | Descriptor: | MAGNESIUM ION, NHP2/L7aE family protein YEL026W | Authors: | Dobbyn, H.C, McEwan, P.A, Bella, J, O'Keefe, R.T. | Deposit date: | 2005-08-05 | Release date: | 2006-10-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants. Biochem.Biophys.Res.Commun., 360, 2007
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2AO6
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![BU of 2ao6 by Molmil](/molmil-images/mine/2ao6) | Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753 peptide and R1881 | Descriptor: | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, 14-mer fragment of Nuclear receptor coactivator 2, androgen receptor | Authors: | He, B, Gampe Jr, R.T, Kole, A.J, Hnat, A.T, Stanley, T.B, An, G, Stewart, E.L, Kalman, R.I, Minges, J.T, Wilson, E.M. | Deposit date: | 2005-08-12 | Release date: | 2005-08-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance Mol.Cell, 16, 2004
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2ZYI
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![BU of 2zyi by Molmil](/molmil-images/mine/2zyi) | A. Fulgidus lipase with fatty acid fragment and calcium | Descriptor: | CALCIUM ION, Lipase, putative, ... | Authors: | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | Deposit date: | 2009-01-22 | Release date: | 2009-06-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
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2ZYH
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![BU of 2zyh by Molmil](/molmil-images/mine/2zyh) | mutant A. Fulgidus lipase S136A complexed with fatty acid fragment | Descriptor: | CALCIUM ION, HEXADECANE, Lipase, ... | Authors: | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | Deposit date: | 2009-01-22 | Release date: | 2009-06-16 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
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2YIE
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![BU of 2yie by Molmil](/molmil-images/mine/2yie) | Crystal structure of a F. nucleatum FMN riboswitch bound to FMN | Descriptor: | FLAVIN MONONUCLEOTIDE, FMN RIBOSWITCH, MAGNESIUM ION, ... | Authors: | Vicens, Q, Mondragon, E, Batey, R.T. | Deposit date: | 2011-05-12 | Release date: | 2011-08-31 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.941 Å) | Cite: | Molecular Sensing by the Aptamer Domain of the Fmn Riboswitch: A General Model for Ligand Binding by Conformational Selection Nucleic Acids Res., 39, 2011
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2ZT6
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![BU of 2zt6 by Molmil](/molmil-images/mine/2zt6) | |
2ZEV
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![BU of 2zev by Molmil](/molmil-images/mine/2zev) | S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with Magnesium, IPP and BPH-715 | Descriptor: | 3-(DECYLOXY)-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase, ... | Authors: | Guo, R.T, Chen, C.K.-M, Cao, R, Oldfield, E, Wang, A.H.-J. | Deposit date: | 2007-12-17 | Release date: | 2008-12-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation J.Am.Chem.Soc., 131, 2009
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1ZJR
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![BU of 1zjr by Molmil](/molmil-images/mine/1zjr) | Crystal Structure of A. aeolicus TrmH/SpoU tRNA modifying enzyme | Descriptor: | GLYCEROL, SULFATE ION, tRNA (Guanosine-2'-O-)-methyltransferase | Authors: | Pleshe, E, Truesdell, J, Batey, R.T. | Deposit date: | 2005-04-30 | Release date: | 2005-08-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus. Acta Crystallogr.,Sect.F, 61, 2005
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2ZEU
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![BU of 2zeu by Molmil](/molmil-images/mine/2zeu) | S. Cerevisiae Geranylgeranyl Pyrophosphate Synthase in Complex with BPH-715 | Descriptor: | 3-(DECYLOXY)-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Geranylgeranyl pyrophosphate synthetase | Authors: | Guo, R.T, Chen, C.K.-M, Cao, R, Oldfield, E, Wang, A.H.-J. | Deposit date: | 2007-12-17 | Release date: | 2008-12-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation J.Am.Chem.Soc., 131, 2009
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2B57
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![BU of 2b57 by Molmil](/molmil-images/mine/2b57) | Guanine Riboswitch C74U mutant bound to 2,6-diaminopurine | Descriptor: | 65-MER, 9H-PURINE-2,6-DIAMINE, ACETATE ION, ... | Authors: | Gilbert, S.D, Stoddard, C.D, Wise, S.J, Batey, R.T. | Deposit date: | 2005-09-27 | Release date: | 2006-05-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain. J.Mol.Biol., 359, 2006
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2AVU
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![BU of 2avu by Molmil](/molmil-images/mine/2avu) | Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription | Descriptor: | Flagellar transcriptional activator flhC, Transcriptional activator flhD, ZINC ION | Authors: | Wang, S, Fleming, R.T, Westbrook, E.M, Matsumura, P, McKay, D.B. | Deposit date: | 2005-08-30 | Release date: | 2005-12-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the Escherichia coli FlhDC Complex, a Prokaryotic Heteromeric Regulator of Transcription. J.Mol.Biol., 355, 2006
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2ZYR
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![BU of 2zyr by Molmil](/molmil-images/mine/2zyr) | A. Fulgidus lipase with fatty acid fragment and magnesium | Descriptor: | Lipase, putative, MAGNESIUM ION, ... | Authors: | Chen, C.K, Ko, T.P, Guo, R.T, Wang, A.H. | Deposit date: | 2009-01-28 | Release date: | 2009-06-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure of the alkalohyperthermophilic Archaeoglobus fulgidus lipase contains a unique C-terminal domain essential for long-chain substrate binding. J.Mol.Biol., 390, 2009
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233D
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![BU of 233d by Molmil](/molmil-images/mine/233d) | THE CRYSTAL STRUCTURE ANALYSIS OF D(CGCGAASSCGCG)2: A SYNTHETIC DNA DODECAMER DUPLEX CONTAINING FOUR 4'-THIO-2'-DEOXYTHYMIDINE NUCLEOTIDES | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*)-D(*(T49)P*(T49)P*)-D(*CP*GP*CP*G)-3') | Authors: | Boggon, T.J, Hancox, E.L, McAuley-Hecht, K.E, Connolly, B.A, Hunter, W.N, Brown, T, Walker, R.T, Leonard, G.A. | Deposit date: | 1995-10-16 | Release date: | 1996-06-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure analysis of d(CGCGAASSCGCG)2, a synthetic DNA dodecamer duplex containing four 4'-thio-2'-deoxythymidine nucleotides. Nucleic Acids Res., 24, 1996
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3AMD
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![BU of 3amd by Molmil](/molmil-images/mine/3amd) | Crystal structures of Thermotoga maritima Cel5A, apo form and tetramer/au | Descriptor: | Endoglucanase | Authors: | Wu, T.H, Huang, C.H, Ko, T.P, Lai, H.L, Ma, Y, Cheng, Y.S, Liu, J.R, Guo, R.T. | Deposit date: | 2010-08-19 | Release date: | 2011-08-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Diverse substrate recognition mechanism revealed by Thermotoga maritima Cel5A structures in complex with cellotetraose, cellobiose and mannotriose Biochim.Biophys.Acta, 1814, 2011
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3AMR
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![BU of 3amr by Molmil](/molmil-images/mine/3amr) | Crystal Structures of Bacillus subtilis Alkaline Phytase in Complex with Ca2+, Co2+, Ni2+, Mg2+ and myo-Inositol Hexasulfate | Descriptor: | 3-phytase, CALCIUM ION, D-MYO-INOSITOL-HEXASULPHATE | Authors: | Zeng, Y.F, Ko, T.P, Lai, H.L, Cheng, Y.S, Wu, T.H, Ma, Y, Yang, C.S, Cheng, K.J, Huang, C.H, Guo, R.T, Liu, J.R. | Deposit date: | 2010-08-22 | Release date: | 2011-04-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal structures of Bacillus alkaline phytase in complex with divalent metal ions and inositol hexasulfate J.Mol.Biol., 409, 2011
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2D2R
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![BU of 2d2r by Molmil](/molmil-images/mine/2d2r) | Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase | Descriptor: | Undecaprenyl Pyrophosphate Synthase | Authors: | Kuo, C.J, Guo, R.T, Chen, C.L, Ko, T.P, Cheng, Y.S, Cheng, Y.L, Liang, P.H, Wang, A.H.-J. | Deposit date: | 2005-09-16 | Release date: | 2006-09-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases. J.Biomed.Biotechnol., 2008, 2008
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4A4L
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![BU of 4a4l by Molmil](/molmil-images/mine/4a4l) | CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITOR | Descriptor: | 1-METHYL-5-(2-{[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO}PYRIMIDIN-4-YL)-1H-PYRROLE-3-CARBOXAMIDE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ... | Authors: | Bertrand, J.A, Bossi, R.T. | Deposit date: | 2011-10-17 | Release date: | 2012-01-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | 5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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4A4O
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![BU of 4a4o by Molmil](/molmil-images/mine/4a4o) | CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 2-(2-AMINO- PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-PYRROLOPYRIDIN-4-ONE INHIBITOR | Descriptor: | 1-METHYL-2-(2-{[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO}PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ... | Authors: | Bertrand, J.A, Bossi, R.T. | Deposit date: | 2011-10-18 | Release date: | 2012-01-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | 5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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1A7A
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![BU of 1a7a by Molmil](/molmil-images/mine/1a7a) | STRUCTURE OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE: DETERMINATION OF A 30 SELENIUM ATOM SUBSTRUCTURE FROM DATA AT A SINGLE WAVELENGTH | Descriptor: | (1'R,2'S)-9-(2-HYDROXY-3'-KETO-CYCLOPENTEN-1-YL)ADENINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-ADENOSYLHOMOCYSTEINE HYDROLASE | Authors: | Turner, M.A, Yuan, C.-S, Borchardt, R.T, Hershfield, M.S, Smith, G.D, Howell, P.L. | Deposit date: | 1998-03-10 | Release date: | 1999-04-20 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength. Nat.Struct.Biol., 5, 1998
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1B69
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![BU of 1b69 by Molmil](/molmil-images/mine/1b69) | |
3KZ0
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![BU of 3kz0 by Molmil](/molmil-images/mine/3kz0) | MCL-1 complex with MCL-1-specific selected peptide | Descriptor: | Induced myeloid leukemia cell differentiation protein Mcl-1, Mcl-1 specific peptide MB7, SULFATE ION, ... | Authors: | Dutta, S, Fire, E, Grant, R.A, Sauer, R.T, Keating, A.E. | Deposit date: | 2009-12-07 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Determinants of BH3 binding specificity for Mcl-1 versus Bcl-xL. J.Mol.Biol., 398, 2010
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6IR2
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![BU of 6ir2 by Molmil](/molmil-images/mine/6ir2) | Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM2 at 1.4 Angstron resolution | Descriptor: | MCherry fluorescent protein, mCherry's nanobody LaM2 | Authors: | Ding, Y, Wang, Z.Y, Hu, R.T, Chen, X. | Deposit date: | 2018-11-09 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.393 Å) | Cite: | Structural insights into the binding of nanobodies LaM2 and LaM4 to the red fluorescent protein mCherry. Protein Sci., 30, 2021
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