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PDB: 2930 件

8D9T
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AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on gamma-Arf1
分子名称: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
6JN2
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Crystal structure of the coiled-coil domains of human DOT1L in complex with AF10
分子名称: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10
著者Song, X, Wang, M, Yang, N, Xu, R.M.
登録日2019-03-13
公開日2019-09-18
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
Proc.Natl.Acad.Sci.USA, 116, 2019
8D9S
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AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1
分子名称: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9U
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AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on beta-Arf1
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
8D9R
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AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on gamma-Arf1
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Hooy, R.M, Hurley, J.H.
登録日2022-06-11
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
1TC6
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Ligand Induced Conformational Shift in the N-terminal Domain of GRP94, Open Conformation ADP-Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
著者Gewirth, D.T, Immormino, R.M, Dollins, D.E, Shaffer, P.L, Walker, M.A, Soldano, K.L.
登録日2004-05-20
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone.
J.Biol.Chem., 279, 2004
4GDO
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BU of 4gdo by Molmil
Structure of a fragment of the rod domain of plectin
分子名称: Plectin
著者De Pereda, J.M, Buey, R.M, Uson, I, Sammito, M.D, De Marino, I.
登録日2012-08-01
公開日2013-09-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Exploiting tertiary structure through local folds for crystallographic phasing.
Nat.Methods, 10, 2013
4FVP
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Crystal structure of the Jak2 pseudokinase domain (apo form)
分子名称: GLYCEROL, Tyrosine-protein kinase JAK2
著者Bandaranayake, R.M, Hubbard, S.R.
登録日2012-06-29
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012
2L9V
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NMR structure of the FF domain L24A mutant's folding transition state
分子名称: Pre-mRNA-processing factor 40 homolog A
著者Korzhnev, D.M, Vernon, R.M, Religa, T.L, Hansen, A, Baker, D, Fersht, A.R, Kay, L.E.
登録日2011-02-24
公開日2011-09-28
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study.
J.Am.Chem.Soc., 133, 2011
7LS5
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Cryo-EM structure of the Pre3-1 20S proteasome core particle
分子名称: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
著者Schnell, H.M, Walsh Jr, R.M, Rawson, S, Hanna, J.W.
登録日2021-02-17
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis.
Nat.Struct.Mol.Biol., 28, 2021
1T60
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Crystal structure of Type IV collagen NC1 domain from bovine lens capsule
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, POTASSIUM ION, ...
著者Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M.
登録日2004-05-05
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links
J.Biol.Chem., 279, 2004
7LS6
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Cryo-EM structure of Pre-15S proteasome core particle assembly intermediate purified from Pre3-1 proteasome mutant (G34D)
分子名称: Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ...
著者Schnell, H.M, Walsh Jr, R.M, Rawson, S, Hanna, J.W.
登録日2021-02-17
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis.
Nat.Struct.Mol.Biol., 28, 2021
7LSX
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BU of 7lsx by Molmil
Cryo-EM structure of 13S proteasome core particle assembly intermediate purified from Pre3-1 proteasome mutant (G34D)
分子名称: Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ...
著者Schnell, H.M, Walsh Jr, R.M, Rawson, S, Hanna, J.W.
登録日2021-02-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis.
Nat.Struct.Mol.Biol., 28, 2021
1ST9
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Crystal Structure of a Soluble Domain of ResA in the Oxidised Form
分子名称: 1,2-ETHANEDIOL, Thiol-disulfide oxidoreductase resA
著者Crow, A, Acheson, R.M, Le Brun, N.E, Oubrie, A.
登録日2004-03-25
公開日2004-05-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis of Redox-coupled Protein Substrate Selection by the Cytochrome c Biosynthesis Protein ResA.
J.Biol.Chem., 279, 2004
2A9W
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BU of 2a9w by Molmil
E. coli TS complexed with dUMP and inhibitor GA9
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-BROMOPHENOL, 3,3-BIS(3-BROMO-4-HYDROXYPHENYL)-7-CHLORO-1H,3H-BENZO[DE]ISOCHROMEN-1-ONE, ...
著者Finer-Moore, J.S, Anderson, A.C, O'Neil, R.H, Costi, M.P, Ferrari, S, Krucinski, J, Stroud, R.M.
登録日2005-07-12
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The structure of Cryptococcus neoformans thymidylate synthase suggests strategies for using target dynamics for species-specific inhibition.
Acta Crystallogr.,Sect.D, 61, 2005
4E02
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Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(S)-2-chloro-3-phenylpropanoic acid complex with AMPPNP
分子名称: (S)-2-chloro-3-phenylpropanoic acid, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Tso, S.C, Chuang, J.L, Gui, W.J, Wynn, R.M, Li, J, Chuang, D.T.
登録日2012-03-02
公開日2013-03-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1547 Å)
主引用文献Structures of branched-chain alpha-ketoacid dehydrogenase kinase-inhibitor complexes
To be Published
1YKI
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BU of 1yki by Molmil
The structure of E. coli nitroreductase bound with the antibiotic nitrofurazone
分子名称: CITRIC ACID, DIMETHYL SULFOXIDE, FLAVIN MONONUCLEOTIDE, ...
著者Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I.
登録日2005-01-18
公開日2005-02-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
1YJ4
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Y305F Trichodiene Synthase
分子名称: 1,2-ETHANEDIOL, Trichodiene synthase
著者Vedula, L.S, Rynkiewicz, M.J, Pyun, H.J, Coates, R.M, Cane, D.E, Christianson, D.W.
登録日2005-01-13
公開日2005-03-29
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants.
Biochemistry, 44, 2005
1YJD
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Crystal structure of human CD28 in complex with the Fab fragment of a mitogenic antibody (5.11A1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment of 5.11A1 antibody heavy chain, Fab fragment of 5.11A1 antibody light chain, ...
著者Evans, E.J, Esnouf, R.M, Manso-Sancho, R, Gilbert, R.J.C, James, J.R, Sorensen, P, Stuart, D.I, Davis, S.J.
登録日2005-01-14
公開日2005-02-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a soluble CD28-Fab complex
Nat.Immunol., 6, 2005
4DXO
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Crystal Structure of a reconstructed Kaede-type Red Fluorescent Protein, LEA X(6)
分子名称: LEA X(6) GFP-LIKE PROTEINS, SODIUM ION
著者Kim, H, Fromme, R, Wachter, R.M.
登録日2012-02-27
公開日2013-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A hinge migration mechanism unlocks the evolution of green-to-red photoconversion in GFP-like proteins.
Structure, 23, 2015
8CT6
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1F8 mAb in complex with the computationally optimized broadly reactive H1 influenza hemagglutinin P1
分子名称: 1F8 heavy chain, 1F8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dzimianski, J.V, DuBois, R.M.
登録日2022-05-13
公開日2023-04-19
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine.
Commun Biol, 6, 2023
4DXN
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Crystal Structure of a reconstructed Kaede-type Red Fluorescent Protein, Least Evolved Ancestor (LEA)
分子名称: LEAST EVOLVED ANCESTOR (LEA) GFP-LIKE PROTEINS, SULFATE ION
著者Kim, H, Fromme, R, Wachter, R.M.
登録日2012-02-27
公開日2013-02-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Acid-Base Catalysis and Crystal Structures of a Least Evolved Ancestral GFP-like Protein Undergoing Green-to-Red Photoconversion.
Biochemistry, 52, 2013
1YMG
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The Channel Architecture of Aquaporin O at 2.2 Angstrom Resolution
分子名称: Lens fiber major intrinsic protein, nonyl beta-D-glucopyranoside
著者Harries, W.E.C, Akhavan, D, Miercke, L.J.W, Khademi, S, Stroud, R.M.
登録日2005-01-20
公開日2005-02-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献The Channel Architecture of Aquaporin 0 at a 2.2-A Resolution
Proc.Natl.Acad.Sci.USA, 101, 2004
4DE9
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LytR-CPS2A-psr family protein YwtF (TagT) with bound octaprenyl pyrophosphate lipid
分子名称: (2Z,6Z,10Z,14Z,18Z,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, Putative transcriptional regulator ywtF
著者Eberhardt, A, Hoyland, C.N, Vollmer, D, Bisle, S, Cleverley, R.M, Johnsborg, O, Havarstein, S, Lewis, R.J, Vollmer, W.
登録日2012-01-20
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献Attachment of Capsular Polysaccharide to the Cell Wall in Streptococcus pneumoniae.
Microb Drug Resist, 18, 2012
1Z1P
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Y66L variant of Enhanced Green Fluorescent Protein with 412-nm Absorbing Chromophore
分子名称: green fluorescent protein
著者Rosenow, M.A, Patel, H.N, Wachter, R.M.
登録日2005-03-04
公開日2005-06-21
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Oxidative Chemistry in the GFP Active Site Leads to Covalent Cross-Linking of a Modified Leucine Side Chain with a Histidine Imidazole: Implications for the Mechanism of Chromophore Formation.
Biochemistry, 44, 2005

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