7LS6

Cryo-EM structure of Pre-15S proteasome core particle assembly intermediate purified from Pre3-1 proteasome mutant (G34D)

Summary for 7LS6

• Entry DOI: 10.2210/pdb7ls6/pdb
• EMDB information: 23503
• Descriptor: Proteasome subunit alpha type-1, Proteasome subunit beta type-3, Proteasome subunit beta type-4, ... (15 entities in total)
• Functional Keywords: core particle, complex, assembly intermediate, hydrolase
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 15
• Total formula weight: 408617.91

Authors

Schnell, H.M.,Walsh Jr, R.M.,Rawson, S.,Hanna, J.W. (deposition date: 2021-02-17, release date: 2021-04-14, Last modification date: 2024-03-06)

• Primary citation: Schnell, H.M.,Walsh Jr., R.M.,Rawson, S.,Kaur, M.,Bhanu, M.K.,Tian, G.,Prado, M.A.,Guerra-Moreno, A.,Paulo, J.A.,Gygi, S.P.,Roelofs, J.,Finley, D.,Hanna, J.; Structures of chaperone-associated assembly intermediates reveal coordinated mechanisms of proteasome biogenesis.; Nat.Struct.Mol.Biol., 28:418-425, 2021; PubMed: 33846632; DOI: 10.1038/s41594-021-00583-9

Experimental method

ELECTRON MICROSCOPY (3.17 Å)