7LS6
Cryo-EM structure of Pre-15S proteasome core particle assembly intermediate purified from Pre3-1 proteasome mutant (G34D)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proteasome subunit alpha type-1 | polymer | 252 | 28033.8 | 1 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein |
| 2 | B (B) | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 1 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7 |
| 3 | C (C) | Proteasome subunit alpha type-3 | polymer | 258 | 28748.2 | 1 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13 |
| 4 | D (D) | Proteasome subunit alpha type-4 | polymer | 254 | 28478.1 | 1 | UniProt (P40303) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6 |
| 5 | E (E) | Proteasome subunit alpha type-5 | polymer | 260 | 28649.1 | 1 | UniProt (P32379) Pfam (PF00227) Pfam (PF10584) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2 |
| 6 | F (F) | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 1 | UniProt (P40302) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5 |
| 7 | G (G) | Proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 1 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1 |
| 8 | H (H) | Proteasome maturation factor UMP1 | polymer | 148 | 16777.8 | 1 | UniProt (P38293) Pfam (PF05348) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | |
| 9 | I (I) | Proteasome subunit beta type-2 | polymer | 261 | 28299.9 | 1 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1 |
| 10 | J (J) | Proteasome subunit beta type-3 | polymer | 205 | 22627.8 | 1 | UniProt (P25451) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3 |
| 11 | K (K) | Proteasome subunit beta type-4 | polymer | 198 | 22545.7 | 1 | UniProt (P22141) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11 |
| 12 | L (O) | Proteasome chaperone 1 | polymer | 276 | 30718.1 | 1 | UniProt (Q05778) Pfam (PF10450) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Proteasome biogenesis-associated protein 1 |
| 13 | M (P) | Proteasome assembly chaperone 2 | polymer | 267 | 30762.9 | 1 | UniProt (P36040) Pfam (PF09754) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Alpha-1-proteinase inhibitor-degradation deficient protein 66,Proteasome biogenesis-associated protein 2 |
| 14 | N (L) | Proteasome subunit beta type-5 | polymer | 287 | 31670.5 | 1 | UniProt (P30656) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2 |
| 15 | O (M) | Proteasome subunit beta type-6 | polymer | 241 | 26905.1 | 1 | UniProt (P23724) Pfam (PF00227) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | Multicatalytic endopeptidase complex subunit C5,Proteasome component C5 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 408617.9 | |
| All* | Total formula weight | 408617.9 |
