5LVP
 
 | | Human PDK1 Kinase Domain in Complex with an HM-Peptide Bound to the PIF-Pocket | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | | 登録日 | 2016-09-14 | | 公開日 | 2016-10-19 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase.
Cell Chem Biol, 23, 2016
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5LVN
 | | Human PDK1 Kinase Domain in Complex with Adenosine Bound to the ATP-Binding Site | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENOSINE, CHLORIDE ION, ... | | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | | 登録日 | 2016-09-14 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.379 Å) | | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase.
Cell Chem Biol, 23, 2016
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5LVM
 | | Human PDK1 Kinase Domain in Complex with Adenine Bound to the ATP-Binding Site | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, ADENINE, DITHIANE DIOL | | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | | 登録日 | 2016-09-14 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase.
Cell Chem Biol, 23, 2016
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1HST
 | | CRYSTAL STRUCTURE OF GLOBULAR DOMAIN OF HISTONE H5 AND ITS IMPLICATIONS FOR NUCLEOSOME BINDING | | 分子名称: | HISTONE H5 | | 著者 | Ramakrishnan, V, Finch, J.T, Graziano, V, Lee, P.L, Sweet, R.M. | | 登録日 | 1993-03-30 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.
Nature, 362, 1993
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5LVO
 | | Human PDK1 Kinase Domain in Complex with Allosteric Compound PSE10 Bound to the PIF-Pocket | | 分子名称: | 2-oxidanylidenepropyl ~{N}-(2-chloranyl-6-fluoranyl-phenyl)carbonyl-~{N}'-(4-chlorophenyl)carbamimidothioate, 3-phosphoinositide-dependent protein kinase 1, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Schulze, J.O, Saladino, G, Busschots, K, Neimanis, S, Suess, E, Odadzic, D, Zeuzem, S, Hindie, V, Herbrand, A.K, Lisa, M.N, Alzari, P.M, Gervasio, F.L, Biondi, R.M. | | 登録日 | 2016-09-14 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase.
Cell Chem Biol, 23, 2016
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7C28
 | | Unusual quaternary structure of a homodimeric synergistic toxin from mamba snake venom | | 分子名称: | SULFATE ION, Synergistic-type venom protein S2C4 | | 著者 | Jobichen, C, Narumi, A, Sivaraman, J, Kini, R.M. | | 登録日 | 2020-05-07 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Unusual quaternary structure of a homodimeric synergistic-type toxin from mamba snake venom defines its molecular evolution.
Biochem.J., 477, 2020
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2OBE
 | | Crystal Structure of Chimpanzee Adenovirus (Type 68/Simian 25) Major Coat Protein Hexon | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, DIHYDROGENPHOSPHATE ION, Hexon protein | | 著者 | Xue, F, Rux, J.J, Burnett, R.M. | | 登録日 | 2006-12-18 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-based identification of a major neutralizing site in an adenovirus hexon
J.Virol., 81, 2007
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1FE2
 | | CRYSTAL STRUCTURE OF DIHOMO-GAMMA-LINOLEIC ACID BOUND IN THE CYCLOOXYGENASE CHANNEL OF PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EICOSA-8,11,14-TRIENOIC ACID, PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1, ... | | 著者 | Thuresson, E.D, Malkowski, M.G, Lakkides, K.M, Smith, W.L, Garavito, R.M. | | 登録日 | 2000-07-20 | | 公開日 | 2001-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases.
J.Biol.Chem., 276, 2001
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1IJC
 | | Solution Structure of Bucandin, a Neurotoxin from the Venom of the Malayan Krait | | 分子名称: | bucandin | | 著者 | Torres, A.M, Kini, R.M, Nirthanan, S, Kuchel, P.W. | | 登録日 | 2001-04-25 | | 公開日 | 2001-12-21 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of bucandin, a neurotoxin from the venom of the Malayan krait (Bungarus candidus).
Biochem.J., 360, 2001
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1JU6
 | | Human Thymidylate Synthase Complex with dUMP and LY231514, A Pyrrolo(2,3-d)pyrimidine-based Antifolate | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, PHOSPHATE ION, ... | | 著者 | Sayre, P.H, Finer-Moore, J.S, Fritz, T.A, Biermann, D, Gates, S.B, MacKellar, W.C, Patel, V.F, Stroud, R.M. | | 登録日 | 2001-08-23 | | 公開日 | 2001-09-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Multi-targeted antifolates aimed at avoiding drug resistance form covalent closed inhibitory complexes with human and Escherichia coli thymidylate synthases.
J.Mol.Biol., 313, 2001
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1JER
 | | CUCUMBER STELLACYANIN, CU2+, PH 7.0 | | 分子名称: | COPPER (II) ION, CUCUMBER STELLACYANIN | | 著者 | Hart, P.J, Nersissian, A.M, Herrmann, R.G, Nalbandyan, R.M, Valentine, J.S, Eisenberg, D. | | 登録日 | 1996-08-21 | | 公開日 | 1997-02-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A missing link in cupredoxins: crystal structure of cucumber stellacyanin at 1.6 A resolution.
Protein Sci., 5, 1996
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1YMG
 | | The Channel Architecture of Aquaporin O at 2.2 Angstrom Resolution | | 分子名称: | Lens fiber major intrinsic protein, nonyl beta-D-glucopyranoside | | 著者 | Harries, W.E.C, Akhavan, D, Miercke, L.J.W, Khademi, S, Stroud, R.M. | | 登録日 | 2005-01-20 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | The Channel Architecture of Aquaporin 0 at a 2.2-A Resolution
Proc.Natl.Acad.Sci.USA, 101, 2004
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7OW0
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1YM7
 | | G Protein-Coupled Receptor Kinase 2 (GRK2) | | 分子名称: | Beta-adrenergic receptor kinase 1 | | 著者 | Lodowski, D.T, Barnhill, J.F, Pyskadlo, R.M, Ghirlando, R, Sterne-Marr, R, Tesmer, J.J.G. | | 登録日 | 2005-01-20 | | 公開日 | 2005-07-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | The role of Gbetagamma and domain interfaces in the activation of G protein-coupled receptor kinase 2
Biochemistry, 44, 2005
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1YLU
 | | The structure of E. coli nitroreductase with bound acetate, crystal form 2 | | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | | 登録日 | 2005-01-19 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
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7OXS
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1YT0
 | | Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ... | | 著者 | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | | 登録日 | 2005-02-09 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
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1YT1
 | | Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL | | 分子名称: | Endoplasmin, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL | | 著者 | Dollins, D.E, Immormino, R.M, Gewirth, D.T. | | 登録日 | 2005-02-09 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
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3NTI
 | | Crystal structure of Tudor and Aubergine [R15(me2s)] complex | | 分子名称: | Maternal protein tudor, peptide from Aubergine | | 著者 | Liu, H.P, Huang, Y, Li, Z.Z, Gong, W.M, Xu, R.M. | | 登録日 | 2010-07-05 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for methylarginine-dependent recognition of Aubergine by Tudor
Genes Dev., 24, 2010
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3NTK
 | | Crystal structure of Tudor | | 分子名称: | Maternal protein tudor | | 著者 | Liu, H.P, Huang, Y, Li, Z.Z, Gong, W.M, Xu, R.M. | | 登録日 | 2010-07-05 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for methylarginine-dependent recognition of Aubergine by Tudor
Genes Dev., 24, 2010
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1YLR
 | | The structure of E.coli nitroreductase with bound acetate, crystal form 1 | | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | | 著者 | Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I. | | 登録日 | 2005-01-19 | | 公開日 | 2005-02-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
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3AID
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1LDA
 | | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL | | 分子名称: | Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside | | 著者 | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | | 登録日 | 2002-04-08 | | 公開日 | 2002-05-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
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1LDI
 | | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL | | 分子名称: | Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside | | 著者 | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | | 登録日 | 2002-04-08 | | 公開日 | 2002-05-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Control of the selectivity of the aquaporin water channel family by global orientational tuning.
Science, 296, 2002
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4V5P
 | | The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome | | 分子名称: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | | 著者 | Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V. | | 登録日 | 2010-12-07 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
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