2WJW
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![BU of 2wjw by Molmil](/molmil-images/mine/2wjw) | Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 1.8 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... | Authors: | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | Deposit date: | 2009-06-01 | Release date: | 2009-08-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors. J.Mol.Biol., 392, 2009
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2VW1
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![BU of 2vw1 by Molmil](/molmil-images/mine/2vw1) | Crystal structure of the NanB sialidase from Streptococcus pneumoniae | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, GLYCEROL, SIALIDASE B | Authors: | Xu, G, Potter, J.A, Russell, R.J.M, Oggioni, M.R, Andrew, P.W, Taylor, G.L. | Deposit date: | 2008-06-13 | Release date: | 2008-06-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Crystal Structure of the Nanb Sialidase from Streptococcus Pneumoniae J.Mol.Biol., 384, 2008
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3NTR
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![BU of 3ntr by Molmil](/molmil-images/mine/3ntr) | Crystal structure of K97V mutant of myo-inositol dehydrogenase from Bacillus subtilis with bound cofactor NAD and inositol | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Van Straaten, K.E, Palmer, D.R.J, Sanders, D.A.R. | Deposit date: | 2010-07-05 | Release date: | 2010-09-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.6503 Å) | Cite: | Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification. Biochem.J., 432, 2010
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4C4N
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![BU of 4c4n by Molmil](/molmil-images/mine/4c4n) | Crystal structure of the Sonic Hedgehog-heparin complex | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, CALCIUM ION, ... | Authors: | Whalen, D.M, Malinauskas, T, Gilbert, R.J.C, Siebold, C. | Deposit date: | 2013-09-05 | Release date: | 2013-10-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural Insights Into Proteoglycan-Shaped Hedgehog Signaling. Proc.Natl.Acad.Sci.USA, 110, 2013
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4C4M
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![BU of 4c4m by Molmil](/molmil-images/mine/4c4m) | Crystal structure of the Sonic Hedgehog-chondroitin-4-sulphate complex | Descriptor: | ACETATE ION, CALCIUM ION, SONIC HEDGEHOG PROTEIN, ... | Authors: | Whalen, D.M, Malinauskas, T, Gilbert, R.J.C, Siebold, C. | Deposit date: | 2013-09-05 | Release date: | 2013-10-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural Insights Into Proteoglycan-Shaped Hedgehog Signaling. Proc.Natl.Acad.Sci.USA, 110, 2013
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4E7X
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![BU of 4e7x by Molmil](/molmil-images/mine/4e7x) | Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase | Descriptor: | ACETATE ION, Poly(A) RNA polymerase protein cid1 | Authors: | Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2012-03-19 | Release date: | 2012-07-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
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3O9Q
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![BU of 3o9q by Molmil](/molmil-images/mine/3o9q) | Effector domain of NS1 from A/PR/8/34 containing a W187A mutation | Descriptor: | Nonstructural protein 1 | Authors: | Kerry, P.S, Lewis, A, Hale, B.G, Hass, C, Taylor, M.A, Randall, R.E, Russell, R.J.M. | Deposit date: | 2010-08-04 | Release date: | 2011-05-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain. Plos One, 6, 2011
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3O9T
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![BU of 3o9t by Molmil](/molmil-images/mine/3o9t) | Effector domain from influenza A/PR/8/34 NS1 | Descriptor: | HEXAETHYLENE GLYCOL, Nonstructural protein 1 | Authors: | Kerry, P.S, Lewis, A, Hale, B.G, Hass, C, Taylor, M.A, Randall, R.E, Russell, R.J.M. | Deposit date: | 2010-08-04 | Release date: | 2011-05-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain. Plos One, 6, 2011
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3O9U
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![BU of 3o9u by Molmil](/molmil-images/mine/3o9u) | Effector domain of influenza A/PR/8/34 NS1 | Descriptor: | Nonstructural protein 1 | Authors: | Kerry, P.S, Lewis, A, Hale, B.G, Hass, C, Taylor, M.A, Randall, R.E, Russell, R.J.M. | Deposit date: | 2010-08-04 | Release date: | 2011-05-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain. Plos One, 6, 2011
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2X44
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![BU of 2x44 by Molmil](/molmil-images/mine/2x44) | Structure of a strand-swapped dimeric form of CTLA-4 | Descriptor: | CYTOTOXIC T-LYMPHOCYTE PROTEIN 4 | Authors: | Sonnen, A.F.-P, Yu, C, Evans, E.J, Stuart, D.I, Davis, S.J, Gilbert, R.J.C. | Deposit date: | 2010-01-28 | Release date: | 2010-04-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Domain Metastability: A Molecular Basis for Immunoglobulin Deposition? J.Mol.Biol., 399, 2010
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2WJX
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![BU of 2wjx by Molmil](/molmil-images/mine/2wjx) | Crystal structure of the human ionotropic glutamate receptor GluR2 ATD region at 4.1 A resolution | Descriptor: | GLUTAMATE RECEPTOR 2 | Authors: | Clayton, A, Siebold, C, Gilbert, R.J.C, Sutton, G.C, Harlos, K, McIlhinney, R.A.J, Jones, E.Y, Aricescu, A.R. | Deposit date: | 2009-06-01 | Release date: | 2009-08-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Crystal Structure of the Glur2 Amino-Terminal Domain Provides Insights Into the Architecture and Assembly of Ionotropic Glutamate Receptors. J.Mol.Biol., 392, 2009
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3MZ0
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![BU of 3mz0 by Molmil](/molmil-images/mine/3mz0) | Crystal structure of apo myo-inositol dehydrogenase from Bacillus subtilis | Descriptor: | CHLORIDE ION, GLYCEROL, Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, ... | Authors: | Van Straaten, K.E, Palmer, D.R.J, Sanders, D.A.R. | Deposit date: | 2010-05-11 | Release date: | 2010-09-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.539 Å) | Cite: | Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification. Biochem.J., 432, 2010
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2XQ5
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![BU of 2xq5 by Molmil](/molmil-images/mine/2xq5) | Pentameric ligand gated ion channel GLIC in complex with tetraethylarsonium (TEAs) | Descriptor: | ARSENIC, GLR4197 PROTEIN | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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2XQ4
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![BU of 2xq4 by Molmil](/molmil-images/mine/2xq4) | Pentameric ligand gated ion channel GLIC in complex with tetramethylarsonium (TMAs) | Descriptor: | ARSENIC, GLR4197 PROTEIN | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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2XQ9
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![BU of 2xq9 by Molmil](/molmil-images/mine/2xq9) | Pentameric ligand gated ion channel GLIC mutant E221A in complex with tetraethylarsonium (TEAs) | Descriptor: | ARSENIC, GLR4197 PROTEIN | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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2XQ8
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![BU of 2xq8 by Molmil](/molmil-images/mine/2xq8) | Pentameric ligand gated ion channel GLIC in complex with zinc ion (Zn2+) | Descriptor: | GLR4197 PROTEIN, ZINC ION | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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1TL7
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![BU of 1tl7 by Molmil](/molmil-images/mine/1tl7) | Complex Of Gs- With The Catalytic Domains Of Mammalian Adenylyl Cyclase: Complex With 2'(3')-O-(N-methylanthraniloyl)-guanosine 5'-triphosphate and Mn | Descriptor: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase, ... | Authors: | Mou, T.C, Gille, A, Seifert, R.J, Sprang, S.R. | Deposit date: | 2004-06-09 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for the inhibition of mammalian membrane adenylyl cyclase by 2 '(3')-O-(N-Methylanthraniloyl)-guanosine 5 '-triphosphate. J.Biol.Chem., 280, 2005
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2XQ6
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![BU of 2xq6 by Molmil](/molmil-images/mine/2xq6) | Pentameric ligand gated ion channel GLIC in complex with cesium ion (Cs+) | Descriptor: | CESIUM ION, GLR4197 PROTEIN | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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2XQA
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![BU of 2xqa by Molmil](/molmil-images/mine/2xqa) | Pentameric ligand gated ion channel GLIC in complex with tetrabutylantimony (TBSb) | Descriptor: | ANTIMONY (III) ION, GLR4197 PROTEIN | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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2XQ7
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![BU of 2xq7 by Molmil](/molmil-images/mine/2xq7) | Pentameric ligand gated ion channel GLIC in complex with cadmium ion (Cd2+) | Descriptor: | CADMIUM ION, GLR4197 PROTEIN | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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2XQ3
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![BU of 2xq3 by Molmil](/molmil-images/mine/2xq3) | Pentameric ligand gated ion channel GLIC in complex with Br-lidocaine | Descriptor: | BROMIDE ION, GLR4197 PROTEIN | Authors: | Hilf, R.J.C, Bertozzi, C, Zimmermann, I, Reiter, A, Trauner, D, Dutzler, R. | Deposit date: | 2010-09-01 | Release date: | 2010-11-10 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-Gated Ion Channel Nat.Struct.Mol.Biol., 17, 2010
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3OSK
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![BU of 3osk by Molmil](/molmil-images/mine/3osk) | Crystal structure of human CTLA-4 apo homodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytotoxic T-lymphocyte protein 4, GLYCEROL | Authors: | Yu, C, Sonnen, A.F.-P, Ikemizu, S, Stuart, D.I, Gilbert, R.J.C, Davis, S.J. | Deposit date: | 2010-09-09 | Release date: | 2010-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Rigid-body ligand recognition drives cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptor triggering J.Biol.Chem., 286, 2011
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4KS1
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![BU of 4ks1 by Molmil](/molmil-images/mine/4ks1) | Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-amino-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | Descriptor: | (3S,4R,5R)-4-(acetylamino)-3-amino-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Kerry, P.S, Russell, R.J.M. | Deposit date: | 2013-05-17 | Release date: | 2013-10-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
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4K2B
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![BU of 4k2b by Molmil](/molmil-images/mine/4k2b) | |
4K2M
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![BU of 4k2m by Molmil](/molmil-images/mine/4k2m) | Crystal structure of ntda from bacillus subtilis in complex with the plp external aldimine adduct with kanosamine-6-phosphate | Descriptor: | 1,2-ETHANEDIOL, 3-deoxy-3-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-6-O-phosphono-alpha-D-gluco pyranose, ACETATE ION, ... | Authors: | Van Straaten, K.E, Palmer, D.R.J, Sanders, D.A.R. | Deposit date: | 2013-04-09 | Release date: | 2013-10-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Subclass of Aminotransferases. J.Biol.Chem., 288, 2013
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