4V1R
 
 | | Structure of a selenomethionine derivative of the GH76 alpha- mannanase BT2949 Bacteroides thetaiotaomicron | | 分子名称: | 1,2-ETHANEDIOL, ALPHA-1,6-MANNANASE, S,R MESO-TARTARIC ACID | | 著者 | Thompson, A.J, Cuskin, F, Spears, R.J, Dabin, J, Turkenburg, J.P, Gilbert, H.J, Davies, G.J. | | 登録日 | 2014-10-02 | | 公開日 | 2015-02-11 | | 最終更新日 | 2015-02-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the Gh76 Alpha-Mannanase Homolog, Bt2949, from the Gut Symbiont Bacteroides Thetaiotaomicron
Acta Crystallogr.,Sect.D, 71, 2015
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5S7J
 | | XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM000893d | | 分子名称: | 1,2-ETHANEDIOL, 1-[(2R)-oxolan-2-yl]methanamine, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ... | | 著者 | Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N. | | 登録日 | 2020-12-11 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | XChem group deposition
To Be Published
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5S7U
 | | XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010938a | | 分子名称: | (4S)-1-methylimidazolidin-4-amine, 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ... | | 著者 | Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N. | | 登録日 | 2020-12-11 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | XChem group deposition
To Be Published
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5S77
 | | XChem group deposition -- Crystal Structure of human ACVR1 in complex with XS035133b | | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type-1, ... | | 著者 | Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N. | | 登録日 | 2020-12-11 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | XChem group deposition
To Be Published
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5S82
 | | XChem group deposition -- Crystal Structure of human ACVR1 in complex with XS035128c | | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, Activin receptor type-1, ... | | 著者 | Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N. | | 登録日 | 2020-12-11 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | XChem group deposition
To Be Published
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5S7B
 | | XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM000329d | | 分子名称: | (3R)-thiolane-3-carboxylic acid, 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ... | | 著者 | Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N. | | 登録日 | 2020-12-11 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | XChem group deposition
To Be Published
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6RPX
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5S7E
 | | XChem group deposition -- Crystal Structure of human ACVR1 in complex with FM010930a | | 分子名称: | (3R)-1,2-oxazolidine-3-carbonitrile, 1,2-ETHANEDIOL, 4-methyl-3-[4-(1-methylpiperidin-4-yl)phenyl]-5-(3,4,5-trimethoxyphenyl)pyridine, ... | | 著者 | Williams, E.P, Adamson, R.J, Smil, D, Krojer, T, Burgess-Brown, N, von Delft, F, Bountra, C, Bullock, A.N. | | 登録日 | 2020-12-11 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | XChem group deposition
To Be Published
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6RPY
 | | Cytokine receptor-like factor 3 C-terminus residues 174-442: Hg-SAD derivative | | 分子名称: | Cytokine receptor-like factor 3, MERCURY (II) ION | | 著者 | Mifsud, R.W, Yan, Y, Bennett, C, Read, R.J. | | 登録日 | 2019-05-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythemia.
Blood, 139, 2022
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6QZH
 | | Structure of the human CC Chemokine Receptor 7 in complex with the intracellular allosteric antagonist Cmp2105 and the insertion protein Sialidase NanA | | 分子名称: | 3-[[4-[[(1~{R})-2,2-dimethyl-1-(5-methylfuran-2-yl)propyl]amino]-1,1-bis(oxidanylidene)-1,2,5-thiadiazol-3-yl]amino]-~{N},~{N},6-trimethyl-2-oxidanyl-benzamide, C-C chemokine receptor type 7,Sialidase A,C-C chemokine receptor type 7, D(-)-TARTARIC ACID, ... | | 著者 | Jaeger, K, Bruenle, S, Weinert, T, Guba, W, Muehle, J, Miyazaki, T, Weber, M, Furrer, A, Haenggi, N, Tetaz, T, Huang, C.Y, Mattle, D, Vonach, J.M, Gast, A, Kuglstatter, A, Rudolph, M.G, Nogly, P, Benz, J, Dawson, R.J.P, Standfuss, J. | | 登録日 | 2019-03-11 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7.
Cell, 178, 2019
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6SB1
 | | Crystal structure of murine perforin-2 P2 domain crystal form 1 | | 分子名称: | CHLORIDE ION, GLYCEROL, Macrophage-expressed gene 1 protein | | 著者 | Ni, T, Ginger, L, Gilbert, R.J.C. | | 登録日 | 2019-07-18 | | 公開日 | 2020-02-05 | | 最終更新日 | 2020-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
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6SB3
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1Y0J
 | | Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of GATA interaction | | 分子名称: | Erythroid transcription factor, ZINC ION, Zinc-finger protein ush | | 著者 | Liew, C.K, Simpson, R.J.Y, Kwan, A.H.Y, Crofts, L.A, Loughlin, F.E, Matthews, J.M, Crossley, M, Mackay, J.P. | | 登録日 | 2004-11-15 | | 公開日 | 2005-01-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/Friend of GATA interaction
Proc.Natl.Acad.Sci.Usa, 102, 2005
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6SB4
 | | Crystal structure of murine perforin-2 P2 domain crystal form 2 | | 分子名称: | Macrophage-expressed gene 1 protein | | 著者 | Ni, T, Yu, X, Ginger, L, Gilbert, R.J.C. | | 登録日 | 2019-07-18 | | 公開日 | 2020-02-05 | | 最終更新日 | 2020-02-26 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity.
Sci Adv, 6, 2020
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5T1A
 | | Structure of CC Chemokine Receptor 2 with Orthosteric and Allosteric Antagonists | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{R})-1-(4-chloranyl-2-fluoranyl-phenyl)-2-cyclohexyl-3-ethanoyl-4-oxidanyl-2~{H}-pyrrol-5-one, (3S)-1-{(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl}-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one, ... | | 著者 | Zheng, Y, Qin, L, Ortiz Zacarias, N.V, de Vries, H, Han, G.W, Gustavsson, M, Dabros, M, Zhao, C, Cherney, R.J, Carter, P, Stamos, D, Abagyan, R, Cherezov, V, Stevens, R.C, IJzerman, A.P, Heitman, L.H, Tebben, A, Kufareva, I, Handel, T.M. | | 登録日 | 2016-08-18 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists.
Nature, 540, 2016
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5TN2
 | | Solution Structure of the C-terminal multimerization domain of the master biofilm-regulator SinR from Bacillus subtilis | | 分子名称: | HTH-type transcriptional regulator SinR | | 著者 | Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J. | | 登録日 | 2016-10-13 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
J.Mol.Biol., 2019
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5TN0
 | | Solution Structure of the N-terminal DNA-binding domain of the master biofilm-regulator SinR from Bacillus subtilis | | 分子名称: | HTH-type transcriptional regulator SinR | | 著者 | Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J. | | 登録日 | 2016-10-13 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
J.Mol.Biol., 2019
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5TDX
 | | Resurrected Ancestral Hydroxynitrile Lyase from Flowering Plants | | 分子名称: | Ancestral Hydroxynitrile Lyase 1, GLYCEROL | | 著者 | Jones, B.J, Evans, R, Wilmot, C.M, Kazlauskas, R.J. | | 登録日 | 2016-09-20 | | 公開日 | 2017-10-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity.
Plos One, 15, 2020
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5TMX
 | | Solution Structure of SinI, antagonist to the master biofilm-regulator SinR in Bacillus subtilis | | 分子名称: | Protein SinI | | 著者 | Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J. | | 登録日 | 2016-10-13 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
J.Mol.Biol., 2019
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5SYQ
 | | Solution structure of Aquifex aeolicus Aq1974 | | 分子名称: | Uncharacterized protein aq_1974 | | 著者 | Sachleben, J.R, Gawlak, G, Hoey, R.J, Liu, G, Joachimiak, A, Montelione, G.T, Koide, S, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-08-11 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Aromatic claw: A new fold with high aromatic content that evades structural prediction.
Protein Sci., 26, 2017
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5U4W
 | | Cryo-EM Structure of Immature Zika Virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ... | | 著者 | Mangala Prasad, V, Miller, A.S, Klose, T, Sirohi, D, Buda, G, Jiang, W, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2016-12-06 | | 公開日 | 2017-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | | 主引用文献 | Structure of the immature Zika virus at 9 angstrom resolution.
Nat. Struct. Mol. Biol., 24, 2017
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5U98
 | | The crystal structure of a self-peptide complexed to Abacavir and HLA-B*57:01 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ... | | 著者 | Ostrov, D.A, Bracey, A.W, Pompeu, Y.A, Jakoncic, J, Buus, S, Buus, A.S, Schutte, R.J. | | 登録日 | 2016-12-15 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Elements Recognized by Abacavir-Induced T Cells.
Int J Mol Sci, 18, 2017
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5U9Z
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5UEI
 | | Crystal Structure of Variable Lymphocyte Receptor (VLR) O13 (Apo) | | 分子名称: | CHLORIDE ION, GLYCEROL, O13 | | 著者 | Gunn, R.J, Collins, B.C, McKitrick, T.R, Cummings, R.D, Herrin, B.R, Cooper, M.D, Wilson, I.A. | | 登録日 | 2017-01-02 | | 公開日 | 2017-10-18 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
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5UF6
 | | The 2.8 A Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparanoid Pentasaccharide | | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, capsid protein VP1 | | 著者 | Xie, Q, Spear, J.M, Noble, A.J, Sousa, D.R, Meyer, N.L, Davulcu, O, Zhang, F, Linhardt, R.J, Stagg, S.M, Chapman, M. | | 登録日 | 2017-01-03 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | The 2.8 angstrom Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide.
Mol Ther Methods Clin Dev, 5, 2017
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