1PK5
 
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3ZR6
 | | STRUCTURE OF GALACTOCEREBROSIDASE FROM MOUSE IN COMPLEX WITH GALACTOSE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Deane, J.E, Graham, S.C, Kim, N.N, Stein, P.E, Mcnair, R, Cachon-Gonzalez, M.B, Cox, T.M, Read, R.J. | | 登録日 | 2011-06-14 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Insights Into Krabbe Disease from Structures of Galactocerebrosidase.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3ZXJ
 | | Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, HIAXHD3, ... | | 著者 | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | | 登録日 | 2011-08-11 | | 公開日 | 2012-04-18 | | 最終更新日 | 2012-05-02 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3ZRZ
 | | Crystal structure of the second and third fibronectin F1 modules in complex with a fragment of Streptococcus pyogenes SfbI-5 | | 分子名称: | FIBRONECTIN, FIBRONECTIN-BINDING PROTEIN, GLYCEROL, ... | | 著者 | Norris, N.C, Bingham, R.J, Potts, J.R. | | 登録日 | 2011-06-21 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Functional Analysis of the Tandem Beta-Zipper Interaction of a Streptococcal Protein with Human Fibronectin.
J.Biol.Chem., 286, 2011
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3ZXK
 | | Engineering the active site of a GH43 glycoside hydrolase generates a biotechnologically significant enzyme that displays both endo- xylanase and exo-arabinofuranosidase activity | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIAXHD3, alpha-L-arabinofuranose-(1-2)-[beta-D-xylopyranose-(1-4)]beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | | 著者 | McKee, L.S, Pena, M.J, Rogowski, A, Jackson, A, Lewis, R.J, York, W.S, Krogh, K.B.R.M, Vikso-Nielsen, A, Skjot, M, Gilbert, H.J, Marles-Wright, J. | | 登録日 | 2011-08-11 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Introducing Endo-Xylanase Activity Into an Exo-Acting Arabinofuranosidase that Targets Side Chains.
Proc.Natl.Acad.Sci.USA, 109, 2012
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1ODP
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1ODR
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1NQ0
 | | TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD | | 分子名称: | ARSENIC, Thyroid hormone receptor beta-1, [4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID | | 著者 | Huber, B.R, Desclozeaux, M, West, B.L, Cunha-Lima, S.T, Nguyen, H.T, Baxter, J.D, Ingraham, H.A, Fletterick, R.J. | | 登録日 | 2003-01-20 | | 公開日 | 2003-04-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain
Mol.Endocrinol., 17, 2003
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1T79
 | | Crystal structure of the androgen receptor ligand binding domain in complex with a FxxLW motif | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, FxxLW motif peptide | | 著者 | Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. | | 登録日 | 2004-05-08 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
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3ZFG
 | | Human enterovirus 71 in complex with capsid binding inhibitor WIN51711 | | 分子名称: | 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, VP1, VP2, ... | | 著者 | Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2012-12-11 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013
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1TK5
 | | T7 DNA polymerase binary complex with 8 oxo guanosine in the templating strand | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*A*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG)P*TP*GP*CP*AP*A)-3', ... | | 著者 | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | | 登録日 | 2004-06-08 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
Embo J., 23, 2004
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1NQ2
 | | Two RTH Mutants with Impaired Hormone Binding | | 分子名称: | ARSENIC, SODIUM ION, Thyroid hormone receptor beta-1, ... | | 著者 | Huber, B.R, Sandler, B, West, B.L, Cunha-Lima, S.T, Nguyen, H.T, Apriletti, J.W, Baxter, J.D, Fletterick, R.J. | | 登録日 | 2003-01-21 | | 公開日 | 2003-04-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Two resistance to thyroid hormone mutants with impaired hormone binding
Mol.Endocrinol., 17, 2003
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1SVU
 | | Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions | | 分子名称: | Modification methylase HhaI, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | 著者 | Dong, A, Zhou, L, Zhang, X, Stickel, S, Roberts, R.J, Cheng, X. | | 登録日 | 2004-03-30 | | 公開日 | 2004-06-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions
Biol.Chem., 385, 2004
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1NTJ
 | | Model of rat Crry determined by solution scattering, curve fitting and homology modelling | | 分子名称: | complement receptor related protein | | 著者 | Aslam, M, Guthridge, J.M, Hack, B.K, Quigg, R.J, Holers, V.M, Perkins, S.J. | | 登録日 | 2003-01-30 | | 公開日 | 2004-02-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | SOLUTION SCATTERING (30 Å) | | 主引用文献 | The Extended Multidomain Solution Structures of the Complement Protein
Crry and its Chimeric Conjugate Crry-Ig by Scattering, Analytical
Ultracentrifugation and Constrained Modelling: Implications for Function and
Therapy
J.Mol.Biol., 329, 2003
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1OPP
 | | PEPTIDE OF HUMAN APOLIPOPROTEIN C-I RESIDUES 1-38, NMR, 28 STRUCTURES | | 分子名称: | APOLIPOPROTEIN C-I | | 著者 | Rozek, A, Buchko, G.W, Kanda, P, Cushley, R.J. | | 登録日 | 1997-05-08 | | 公開日 | 1998-05-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformational studies of the N-terminal lipid-associating domain of human apolipoprotein C-I by CD and 1H NMR spectroscopy.
Protein Sci., 6, 1997
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1T45
 | | STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE | | 分子名称: | Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | | 著者 | Mol, C.D, Dougan, D.R, Schneider, T.R, Skene, R.J, Kraus, M.L, Scheibe, D.N, Snell, G.P, Zou, H, Sang, B.C, Wilson, K.P. | | 登録日 | 2004-04-28 | | 公開日 | 2004-06-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase.
J.Biol.Chem., 279, 2004
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1T64
 | | Crystal Structure of human HDAC8 complexed with Trichostatin A | | 分子名称: | CALCIUM ION, Histone deacetylase 8, SODIUM ION, ... | | 著者 | Somoza, J.R, Skene, R.J, Katz, B.A, Mol, C, Ho, J.D, Jennings, A.J, Luong, C, Arvai, A, Buggy, J.J, Chi, E, Tang, J, Sang, B.-C, Verner, E, Wynands, R, Leahy, E.M, Dougan, D.R, Snell, G, Navre, M, Knuth, M.W, Swanson, R.V, McRee, D.E, Tari, L.W. | | 登録日 | 2004-05-05 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Snapshots of Human HDAC8 Provide Insights into the Class I Histone Deacetylases
Structure, 12, 2004
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1TK0
 | | T7 DNA polymerase ternary complex with 8 oxo guanosine and ddCTP at the insertion site | | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', ... | | 著者 | Brieba, L.G, Eichman, B.F, Kokoska, R.J, Doublie, S, Kunkel, T.A, Ellenberger, T. | | 登録日 | 2004-06-07 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the dual coding potential of 8-oxoguanosine by a high-fidelity DNA polymerase.
Embo J., 23, 2004
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1T7A
 | | Crystal structure of mutant Lys8Asp of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | | 分子名称: | Alpha-like neurotoxin BmK-I | | 著者 | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | | 登録日 | 2004-05-08 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins
J.Mol.Biol., 341, 2004
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1T7F
 | | Crystal structure of the androgen receptor ligand binding domain in complex with a LxxLL motif | | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, LxxLL motif peptide | | 著者 | Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. | | 登録日 | 2004-05-10 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
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1T7M
 | | Crystal structure of the androgen receptor ligand binding domain in complex with a FxxYF motif | | 分子名称: | 1,2-ETHANEDIOL, 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, ... | | 著者 | Hur, E, Pfaff, S.J, Payne, E.S, Gron, H, Buehrer, B.M, Fletterick, R.J. | | 登録日 | 2004-05-10 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Recognition and accommodation at the androgen receptor coactivator binding interface.
Plos Biol., 2, 2004
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4B2O
 | | Crystal structure of Bacillus subtilis YmdB, a global regulator of late adaptive responses. | | 分子名称: | FE (II) ION, PHOSPHATE ION, YMDB PHOSPHODIESTERASE | | 著者 | Newman, J.A, Diethmaier, C, Kovacs, A.T, Rodrigues, C, Kuipers, O.P, Stulke, J, Lewis, R.J. | | 登録日 | 2012-07-17 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | The Ymdb Phosphodiesterase is a Global Regulator of Late Adaptive Responses in Bacillus Subtilis.
J.Bacteriol., 196, 2014
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1T8T
 | | Crystal Structure of human 3-O-Sulfotransferase-3 with bound PAP | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, CITRIC ACID, heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1 | | 著者 | Moon, A.F, Edavettal, S.C, Krahn, J.M, Munoz, E.M, Negishi, M, Linhardt, R.J, Liu, J, Pedersen, L.C. | | 登録日 | 2004-05-13 | | 公開日 | 2004-08-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1
J.Biol.Chem., 279, 2004
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1ONT
 | | NMDA RECEPTOR ANTAGONIST, CONANTOKIN-T, NMR, 17 STRUCTURES | | 分子名称: | CONANTOKIN-T | | 著者 | Skjaerbaek, N, Nielsen, K.J, Lewis, R.J, Alewood, P.F, Craik, D.J. | | 登録日 | 1996-08-27 | | 公開日 | 1997-09-04 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determination of the solution structures of conantokin-G and conantokin-T by CD and NMR spectroscopy.
J.Biol.Chem., 272, 1997
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4B12
 | | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 23) | | 分子名称: | 1-[3-methyl-4-(piperidin-4-yloxy)-1-benzofuran-2-yl]-3-phenylpropan-1-one, 2-oxopentadecyl-CoA, CHLORIDE ION, ... | | 著者 | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | 登録日 | 2012-07-06 | | 公開日 | 2012-10-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery.
J.Med.Chem., 55, 2012
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