4A5M
 
 | | Redox regulator HypR in its oxidized form | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR YYBR | | Authors: | Palm, G.J, Waack, P, Read, R.J, Hinrichs, W. | | Deposit date: | 2011-10-26 | | Release date: | 2012-01-11 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Insights Into the Redox-Switch Mechanism of the Marr/Duf24-Type Regulator Hypr
Nucleic Acids Res., 40, 2012
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8R3C
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4B14
 | | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 26) | | Descriptor: | 2-oxopentadecyl-CoA, 3-methoxybenzyl 3-methyl-4-(piperidin-4-yloxy)-1-benzofuran-2-carboxylate, CHLORIDE ION, ... | | Authors: | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | Deposit date: | 2012-07-06 | | Release date: | 2012-10-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery.
J.Med.Chem., 55, 2012
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4B24
 | | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | | Descriptor: | 5'-D(*CP*GP*AP*TP*AP*GP*GP*TP*AP*GP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*TP*AP*TP*CP*GP)-3', PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE 2 | | Authors: | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | | Deposit date: | 2012-07-12 | | Release date: | 2013-01-09 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2.
Structure, 21, 2013
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4AXI
 | | Structure of the Clostridium difficile EutS protein | | Descriptor: | ETHANOLAMINE CARBOXYSOME STRUCTURAL PROTEIN, GLYCEROL | | Authors: | Pitts, A.C, Tuck, L.R, Faulds-Pain, A, Lewis, R.J, Marles-Wright, J. | | Deposit date: | 2012-06-13 | | Release date: | 2012-06-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Structural Insight Into the Clostridium Difficile Ethanolamine Utilisation Microcompartment.
Plos One, 7, 2012
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4BKG
 | | crystal structure of human diSUMO-2 | | Descriptor: | SMALL UBIQUITIN-RELATED MODIFIER 2 | | Authors: | Keusekotten, K, Bade, V.N, Meyer-Teschendorf, K, Sriramachandran, A, Fischer-Schrader, K, Krause, A, Horst, C, Hofmann, K, Dohmen, R.J, Praefcke, G.J.K. | | Deposit date: | 2013-04-25 | | Release date: | 2013-11-06 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Multivalent Interactions of the Sumo-Interaction Motifs in the Ring-Finger Protein 4 (Rnf4) Determine the Specificity for Chains of the Small Ubiquitin-Related Modifier (Sumo).
Biochem.J., 457, 2014
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5SX4
 | | Crystal Structure of panitumumab in complex with epidermal growth factor receptor domain 3. | | Descriptor: | 1,2-ETHANEDIOL, Epidermal growth factor receptor, GLYCEROL, ... | | Authors: | Sickmier, E.A, Kurzeja, R.J.M, Michelsen, K, Mukta, V, Yang, E, Tasker, A.S. | | Deposit date: | 2016-08-09 | | Release date: | 2016-10-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The Panitumumab EGFR Complex Reveals a Binding Mechanism That Overcomes Cetuximab Induced Resistance.
Plos One, 11, 2016
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4B2O
 | | Crystal structure of Bacillus subtilis YmdB, a global regulator of late adaptive responses. | | Descriptor: | FE (II) ION, PHOSPHATE ION, YMDB PHOSPHODIESTERASE | | Authors: | Newman, J.A, Diethmaier, C, Kovacs, A.T, Rodrigues, C, Kuipers, O.P, Stulke, J, Lewis, R.J. | | Deposit date: | 2012-07-17 | | Release date: | 2013-07-24 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | The Ymdb Phosphodiesterase is a Global Regulator of Late Adaptive Responses in Bacillus Subtilis.
J.Bacteriol., 196, 2014
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4B20
 | | Structural basis of DNA loop recognition by Endonuclease V | | Descriptor: | 5'-D(*AP*TP*CP*TP*TP*GP*TP*CP*GP*CP)-3', 5'-D(*GP*CP*GP*AP*CP*AP*GP)-3', ENDONUCLEASE V, ... | | Authors: | Rosnes, I, Rowe, A.D, Forstrom, R.J, Alseth, I, Bjoras, M, Dalhus, B. | | Deposit date: | 2012-07-12 | | Release date: | 2013-04-17 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural Basis of DNA Loop Recognition by Endonuclease V.
Structure, 21, 2013
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8R3B
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4BCU
 | | Satellite Tobacco Necrosis Virus (STNV) virus like particle in complex with the B3 aptamer | | Descriptor: | CALCIUM ION, COAT PROTEIN | | Authors: | Ford, R.J, Barker, A.M, Bakker, S.E, Coutts, R.H, Ranson, N.A, Phillips, S.E.V, Pearson, A.R, Stockley, P.G. | | Deposit date: | 2012-10-03 | | Release date: | 2013-01-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Sequence-Specific, RNA-Protein Interactions Overcome Electrostatic Barriers Preventing Assembly of Satellite Tobacco Necrosis Virus Coat Protein.
J.Mol.Biol., 425, 2013
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4BOM
 | | Structure of herpesvirus fusion glycoprotein B-bilayer complex revealing the protein-membrane and lateral protein-protein interaction | | Descriptor: | ENVELOPE GLYCOPROTEIN B | | Authors: | Maurer, U.E, Zeev-Ben-Mordehai, Z, Pandurangan, A.P, Cairns, T.M, Hannah, B.P, Whitbeck, J.C, Eisenberg, R.J, Cohen, G.H, Topf, M, Huiskonen, J.T, Grunewald, K. | | Deposit date: | 2013-05-21 | | Release date: | 2013-07-31 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (27 Å) | | Cite: | The structure of herpesvirus fusion glycoprotein B-bilayer complex reveals the protein-membrane and lateral protein-protein interaction.
Structure, 21, 2013
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8R3D
 | | Crystal structure of Pent only at pH 8.8 | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, Beta propeller | | Authors: | Flood, R.J, Crowley, P.B. | | Deposit date: | 2023-11-08 | | Release date: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Multivalent Calixarene Complexation of a Designed Pentameric Lectin.
Biomacromolecules, 25, 2024
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4AUT
 | | Crystal structure of the tuberculosis drug target Decaprenyl- Phosphoryl-beta-D-Ribofuranose-2-oxidoreductase (DprE1) from Mycobacterium smegmatis | | Descriptor: | DECAPRENYL-PHOSPHORYL-BETA-D-RIBOFURANOSE-2-OXIDOREDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Neres, J, Pojer, F, Molteni, E, Chiarelli, L.R, Dhar, N, Boy-Rottger, S, Buroni, S, Fullam, E, Degiacomi, G, Lucarelli, A, Read, R.J, Zanoni, G, Edmondson, D.E, De Rossi, E, Pasca, M, Riccardi, G, Mattevi, A, Dyson, P.J, Cole, S.T, Binda, C. | | Deposit date: | 2012-05-21 | | Release date: | 2012-09-05 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium Tuberculosis.
Sci. Transl. Med., 4, 2012
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4B11
 | | Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 13) | | Descriptor: | 2-oxopentadecyl-CoA, 3-methyl-N-(naphthalen-1-ylmethyl)-4-piperidin-4-yloxy-1-benzofuran-2-carboxamide, CHLORIDE ION, ... | | Authors: | Yu, Z, Brannigan, J.A, Moss, D.K, Brzozowski, A.M, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | Deposit date: | 2012-07-06 | | Release date: | 2012-10-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Design and Synthesis of Inhibitors of Plasmodium Falciparum N-Myristoyltransferase, a Promising Target for Anti-Malarial Drug Discovery.
J.Med.Chem., 55, 2012
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5DAE
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4AXJ
 | | Structure of the Clostridium difficile EutM protein | | Descriptor: | ETHANOLAMINE CARBOXYSOME STRUCTURAL PROTEIN, SULFATE ION | | Authors: | Pitts, A.C, Tuck, L.R, Faulds-Pain, A, Lewis, R.J, Marles-Wright, J. | | Deposit date: | 2012-06-13 | | Release date: | 2012-06-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structural Insight Into the Clostridium Difficile Ethanolamine Utilisation Microcompartment.
Plos One, 7, 2012
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3ZNN
 | | IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN | | Descriptor: | 4H-THIENO[3,2-B]PYROLE-5-CARBOXYLIC ACID, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H. | | Deposit date: | 2013-02-15 | | Release date: | 2013-05-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
J.Med.Chem., 56, 2013
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3ZS9
 | | S. cerevisiae Get3-ADP-AlF4- complex with a cytosolic Get2 fragment | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATPASE GET3, GOLGI TO ER TRAFFIC PROTEIN 2, ... | | Authors: | Mariappan, M, Mateja, A, Dobosz, M, Bove, E, Hegde, R.S, Keenan, R.J. | | Deposit date: | 2011-06-24 | | Release date: | 2011-09-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | The Mechanism of Membrane-Associated Steps in Tail-Anchored Protein Insertion.
Nature, 477, 2011
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3ZNP
 | | IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN | | Descriptor: | 3-HYDROXY-2H-CHROMEN-2-ONE, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H. | | Deposit date: | 2013-02-15 | | Release date: | 2013-05-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
J.Med.Chem., 56, 2013
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3ZNQ
 | | IN VITRO AND IN VIVO INHIBITION OF HUMAN D-AMINO ACID OXIDASE: REGULATION OF D-SERINE CONCENTRATION IN THE BRAIN | | Descriptor: | 3-PHENETHYL-4H-FURO[3,2-B]PYRROLE-5-CARBOXYLIC ACID, D-AMINO-ACID OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Hopkins, S.C, Heffernan, M.L.R, Saraswat, L.D, Bowen, C.A, Melnick, L, Hardy, L.W, Orsini, M.A, Allen, M.S, Koch, P, Spear, K.L, Foglesong, R.J, Soukri, M, Chytil, M, Fang, Q.K, Jones, S.W, Varney, M.A, Panatier, A, Oliet, S.H.R, Pollegioni, L, Piubelli, L, Molla, G, Nardini, M, Large, T.H. | | Deposit date: | 2013-02-15 | | Release date: | 2013-05-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural, Kinetic, and Pharmacodynamic Mechanisms of D-Amino Acid Oxidase Inhibition by Small Molecules.
J.Med.Chem., 56, 2013
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4AD4
 | | Structure of the GH99 endo-alpha-mannosidase from Bacteroides xylanisolvens in complex with glucose-1,3-isofagomine and alpha-1,2- mannobiose | | Descriptor: | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCOSYL HYDROLASE FAMILY 71, alpha-D-glucopyranose, ... | | Authors: | Thompson, A.J, Williams, R.J, Hakki, Z, Alonzi, D.S, Wennekes, T, Gloster, T.M, Songsrirote, K, Thomas-Oates, J.E, Wrodnigg, T.M, Spreitz, J, Stuetz, A.E, Butters, T.D, Williams, S.J, Davies, G.J. | | Deposit date: | 2011-12-21 | | Release date: | 2012-02-01 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and Mechanistic Insight Into N-Glycan Processing by Endo-Alpha-Mannosidase.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4AKB
 | | Structure of Galactose Binding lectin from Champedak (CGB) with Galactose | | Descriptor: | AGGLUTININ ALPHA CHAIN, AGGLUTININ BETA-4 CHAIN, HEXAETHYLENE GLYCOL, ... | | Authors: | Gabrielsen, M, Abdul-Rahman, P.S, Othman, S, Hashim, O.H, Cogdell, R.J. | | Deposit date: | 2012-02-22 | | Release date: | 2013-02-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structures and Binding Specificity of Galactose- and Mannose-Binding Lectins from Champedak: Differences from Jackfruit Lectins
Acta Crystallogr.,Sect.F, 70, 2014
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4AAX
 | | CpGH89CBM32-5, from Clostridium perfringens, in complex with N- acetylgalactosamine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, ALPHA-N-ACETYLGLUCOSAMINIDASE, CALCIUM ION, ... | | Authors: | Ficko-Blean, E, Stuart, C.P, Suits, M.D, Cid, M, Tessier, M, Woods, R.J, Boraston, A.B. | | Deposit date: | 2011-12-05 | | Release date: | 2012-04-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Carbohydrate Recognition by an Architecturally Complex Alpha-N-Acetylglucosaminidase from Clostridium Perfringens.
Plos One, 7, 2012
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4AB5
 | | Regulatory domain structure of NMB2055 (MetR) a LysR family regulator from N. meningitidis | | Descriptor: | TRANSCRIPTIONAL REGULATOR, LYSR FAMILY | | Authors: | Sainsbury, S, Ren, J, Saunders, N.J, Stuart, D.I, Owens, R.J. | | Deposit date: | 2011-12-07 | | Release date: | 2012-07-11 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Structure of the Regulatory Domain of the Lysr Family Regulator Nmb2055 (Metr-Like Protein) from Neisseria Meningitidis
Acta Crystallogr.,Sect.F, 68, 2012
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