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4AKB

Structure of Galactose Binding lectin from Champedak (CGB) with Galactose

Summary for 4AKB
Entry DOI10.2210/pdb4akb/pdb
Related4AK4 4AKC 4AKD
DescriptorAGGLUTININ ALPHA CHAIN, AGGLUTININ BETA-4 CHAIN, HEXAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywordssugar binding protein, lectin
Biological sourceARTOCARPUS INTEGER
More
Total number of polymer chains8
Total formula weight68106.17
Authors
Gabrielsen, M.,Abdul-Rahman, P.S.,Othman, S.,Hashim, O.H.,Cogdell, R.J. (deposition date: 2012-02-22, release date: 2013-02-27, Last modification date: 2023-12-20)
Primary citationGabrielsen, M.,Abdul-Rahman, P.S.,Othman, S.,Hashim, O.H.,Cogdell, R.J.
Structures and Binding Specificity of Galactose- and Mannose-Binding Lectins from Champedak: Differences from Jackfruit Lectins
Acta Crystallogr.,Sect.F, 70:709-, 2014
Cited by
PubMed Abstract: Galactose-binding and mannose-binding lectins from the champedak fruit, which is native to South-east Asia, exhibit useful potential clinical applications. The specificity of the two lectins for their respective ligands allows the detection of potential cancer biomarkers and monitoring of the glycosylated state of proteins in human serum and/or urine. To fully understand and expand the use of these natural proteins, their complete sequences and crystal structures are presented here, together with details of sugar binding.
PubMed: 24915077
DOI: 10.1107/S2053230X14008966
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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