8BMT
 
 | | Structure of GroEL:GroES-ATP complex plunge frozen 200 ms after reaction initiation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, Co-chaperonin GroES, ... | | Authors: | Dhurandhar, M, Efremov, R, Torino, S. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BK8
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8BLC
 | | Structure of the GroEL-ATP complex plunge-frozen 50 ms after mixing with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, MAGNESIUM ION, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-09 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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8BMD
 | | Structure of GroEL-ATP complex under continuous turnover conditions | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperonin GroEL, MAGNESIUM ION, ... | | Authors: | Dhurandhar, M, Torino, S, Efremov, R. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Time-resolved cryo-EM using a combination of droplet microfluidics with on-demand jetting.
Nat.Methods, 20, 2023
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4G9H
 | | Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target EFI-501894, with bound glutathione | | Descriptor: | GLUTATHIONE, GLYCEROL, Glutathione S-transferase | | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | Deposit date: | 2012-07-23 | | Release date: | 2012-08-15 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione
To be Published
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1GMY
 | | Cathepsin B complexed with dipeptidyl nitrile inhibitor | | Descriptor: | 2-AMINOETHANIMIDIC ACID, 3-METHYLPHENYLALANINE, CATHEPSIN B, ... | | Authors: | Greenspan, P.D, Clark, K.L, Tommasi, R.A, Cowen, S.D, McQuire, L.W, Farley, D.L, van Duzer, J.H, Goldberg, R.L, Zhou, H, Du, Z, Fitt, J.J, Coppa, D.E, Fang, Z, Macchia, W, Zhu, L, Capparelli, M.P, Goldstein, R, Wigg, A.M, Doughty, J.R, Bohacek, R.S, Knap, A.K. | | Deposit date: | 2001-09-25 | | Release date: | 2002-09-19 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B Through Structure-Based Drug Design
J.Med.Chem., 44, 2001
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8KHG
 | | Itaconyl-CoA hydratase PaIch | | Descriptor: | CITRIC ACID, Itaconyl-CoA hydratase | | Authors: | Huang, Q, Bao, R. | | Deposit date: | 2023-08-21 | | Release date: | 2024-05-15 | | Last modified: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and functional characterization of itaconyl-CoA hydratase and citramalyl-CoA lyase involved in itaconate metabolism of Pseudomonas aeruginosa.
Structure, 32, 2024
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8JMS
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8K8B
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1JVA
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8KHL
 | | (S)-citramalyl-CoA lyase | | Descriptor: | COENZYME A, Probable acyl-CoA lyase beta chain | | Authors: | Huang, Q, Bao, R. | | Deposit date: | 2023-08-22 | | Release date: | 2024-05-15 | | Last modified: | 2024-07-24 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and functional characterization of itaconyl-CoA hydratase and citramalyl-CoA lyase involved in itaconate metabolism of Pseudomonas aeruginosa.
Structure, 32, 2024
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1JD7
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8KFP
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8IMS
 | | Crystal structure of TRAF7 coiled-coil domain | | Descriptor: | E3 ubiquitin-protein ligase TRAF7 | | Authors: | Hu, R, Lin, L, Lu, Q. | | Deposit date: | 2023-03-07 | | Release date: | 2024-01-24 | | Last modified: | 2024-07-17 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development.
J Mol Cell Biol, 16, 2024
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1JAQ
 | | COMPLEX OF 1-HYDROXYLAMINE-2-ISOBUTYLMALONYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | | Descriptor: | CALCIUM ION, MATRIX METALLO PROTEINASE-8 (MET80 FORM), N-[(2R)-2-(hydroxycarbamoyl)-4-methylpentanoyl]-L-alanylglycinamide, ... | | Authors: | Grams, F, Reinemer, P, Powers, J.C, Kleine, T, Piper, M, Tschesche, H, Huber, R, Bode, W. | | Deposit date: | 1996-03-11 | | Release date: | 1996-07-11 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
Eur.J.Biochem., 228, 1995
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4ISD
 | | Crystal structure of GLUTATHIONE TRANSFERASE homolog from BURKHOLDERIA GL BGR1, TARGET EFI-501803, with bound glutathione | | Descriptor: | GLUTATHIONE, Glutathione S-transferase | | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | Deposit date: | 2013-01-16 | | Release date: | 2013-02-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structure of GLUTATHIONE TRANSFERASE homolog from BURKHOLDERIA GL BGR1, TARGET EFI-501803, with bound glutathione
TO BE PUBLISHED
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4IVF
 | | Crystal structure of glutathione transferase homolog from Lodderomyces elongisporus, target EFI-501753, with two GSH per subunit | | Descriptor: | CITRIC ACID, GLUTATHIONE, Putative uncharacterized protein | | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Armstrong, R.N, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | Deposit date: | 2013-01-22 | | Release date: | 2013-02-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of glutathione transferase homolog from Lodderomyces elongisporus, target EFI-501753, with two GSH per subunit
To be Published
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2HQ6
 | | Structure of the Cyclophilin_CeCYP16-Like Domain of the Serologically Defined Colon Cancer Antigen 10 from Homo Sapiens | | Descriptor: | GLYCEROL, IODIDE ION, Serologically defined colon cancer antigen 10 | | Authors: | Walker, J.R, Davis, T, Paramanathan, R, Newman, E.M, Finerty Jr, P.J, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-07-18 | | Release date: | 2006-08-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.
PLoS Biol., 8, 2010
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8I9R
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State 5S RNP | | Descriptor: | 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9V
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-2 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9X
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9W
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Dbp10-3 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8I9Y
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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8IA0
 | | Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6 | | Descriptor: | 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ... | | Authors: | Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J. | | Deposit date: | 2023-02-07 | | Release date: | 2023-05-17 | | Last modified: | 2023-07-19 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
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6VRS
 | | Single particle reconstruction of glucose isomerase from Streptomyces rubiginosus based on data acquired in the presence of substantial aberrations | | Descriptor: | MANGANESE (II) ION, xylose isomerase | | Authors: | Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. | | Deposit date: | 2020-02-09 | | Release date: | 2020-02-19 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | High-resolution cryo-EM reconstructions in the presence of substantial aberrations
Iucrj, 7, 2020
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