6Y2Q
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![BU of 6y2q by Molmil](/molmil-images/mine/6y2q) | Escherichia coli RnlA endoribonuclease | Descriptor: | CHLORIDE ION, mRNA endoribonuclease toxin LS | Authors: | Garcia-Rodriguez, G, Loris, R. | Deposit date: | 2020-02-17 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Alternative dimerization is required for activity and inhibition of the HEPN ribonuclease RnlA. Nucleic Acids Res., 49, 2021
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7ZV5
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6YQ5
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![BU of 6yq5 by Molmil](/molmil-images/mine/6yq5) | Hybrid structure of the SPP1 tail tube by solid-state NMR and cryo EM - NMR Ensemble | Descriptor: | Tail tube protein gp17.1* | Authors: | Zinke, M, Sachowsky, K.A.A, Zinn-Justin, S, Ravelli, R, Schroder, G.F, Habeck, M, Lange, A. | Deposit date: | 2020-04-16 | Release date: | 2020-10-14 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | Cite: | Architecture of the flexible tail tube of bacteriophage SPP1. Nat Commun, 11, 2020
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6YVW
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![BU of 6yvw by Molmil](/molmil-images/mine/6yvw) | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with monocyclic BB-328 | Descriptor: | 4-[(5-bromanyl-4,6-dimethyl-pyridin-2-yl)amino]-4-oxidanylidene-butanoic acid, Egl nine homolog 1, FE (III) ION, ... | Authors: | Chowdhury, R, Banerji, B, Schofield, C.J. | Deposit date: | 2020-04-28 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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6YW1
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3W63
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![BU of 3w63 by Molmil](/molmil-images/mine/3w63) | MamM-CTD 215-293 | Descriptor: | Magnetosome protein MamM, SULFATE ION | Authors: | Zeytuni, N, Davidov, G, Zarivach, R. | Deposit date: | 2013-02-10 | Release date: | 2014-04-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Cation diffusion facilitators transport initiation and regulation is mediated by cation induced conformational changes of the cytoplasmic domain Plos One, 9, 2014
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6YW3
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3W5Y
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![BU of 3w5y by Molmil](/molmil-images/mine/3w5y) | MamM-CTD | Descriptor: | Magnetosome protein MamM, SULFATE ION | Authors: | Zeytuni, N, Davidov, G, Zarivach, R. | Deposit date: | 2013-02-10 | Release date: | 2014-04-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Cation diffusion facilitators transport initiation and regulation is mediated by cation induced conformational changes of the cytoplasmic domain Plos One, 9, 2014
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3W65
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![BU of 3w65 by Molmil](/molmil-images/mine/3w65) | MamM-CTD D249A and H264A | Descriptor: | Magnetosome protein MamM, SULFATE ION | Authors: | Zeytuni, N, Davidov, G, Zarivach, R. | Deposit date: | 2013-02-10 | Release date: | 2014-04-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Cation diffusion facilitators transport initiation and regulation is mediated by cation induced conformational changes of the cytoplasmic domain Plos One, 9, 2014
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2WF3
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![BU of 2wf3 by Molmil](/molmil-images/mine/2wf3) | Human BACE-1 in complex with 6-(ethylamino)-N-((1S,2R)-2-hydroxy-3-(((3-(methyloxy)phenyl)methyl)amino)-1-(phenylmethyl)propyl)-1-methyl-1, 3,4,5-tetrahydro-2,1-benzothiazepine-8-carboxamide 2,2-dioxide | Descriptor: | BETA-SECRETASE 1, GLYCEROL, N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-6-(ETHYLAMINO)-1-METHYL-1,3,4,5-TETRAHYDRO-2,1-BENZOTHIAZEPINE-8-CARBOXAMIDE 2,2-DIOXIDE | Authors: | Charrier, N, Clarke, B, Demont, E, Dingwall, C, Dunsdon, R, Hawkins, J, Hubbard, J, Hussain, I, Maile, G, Matico, R, Mosley, J, Naylor, A, O'Brien, A, Redshaw, S, Rowland, P, Soleil, V, Smith, K.J, Sweitzer, S, Theobald, P, Vesey, D, Walter, D.S, Wayne, G. | Deposit date: | 2009-04-02 | Release date: | 2009-05-19 | Last modified: | 2019-05-15 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Second Generation of Bace-1 Inhibitors Part 2: Optimisation of the Non-Prime Side Substituent. Bioorg.Med.Chem.Lett., 19, 2009
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8APX
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2PKV
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![BU of 2pkv by Molmil](/molmil-images/mine/2pkv) | D-(GGTATACC) ambient pressure | Descriptor: | 5'-D(*GP*GP*TP*AP*TP*AP*CP*C)-3' | Authors: | Girard, E, Prange, T, Kahn, R, Fourme, R. | Deposit date: | 2007-04-18 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Adaptation of the base-paired double-helix molecular architecture to extreme pressure. Nucleic Acids Res., 35, 2007
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8AOV
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6YVZ
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![BU of 6yvz by Molmil](/molmil-images/mine/6yvz) | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with bicyclic JLS-367 | Descriptor: | 4-[(5-bromanylisoquinolin-3-yl)amino]-4-oxidanylidene-butanoic acid, BICARBONATE ION, Egl nine homolog 1, ... | Authors: | Chowdhury, R, Sorensen, J.L, Schofield, C.J. | Deposit date: | 2020-04-29 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Use of cyclic peptides to induce crystallization: case study with prolyl hydroxylase domain 2. Sci Rep, 10, 2020
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8APU
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![BU of 8apu by Molmil](/molmil-images/mine/8apu) | Crystal Structure of H. influenzae TrmD in complex with Compound 14 | Descriptor: | 6-[[4-(aminomethyl)phenyl]methylamino]pyridine-3-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Hall, G, Cowan, R, Carr, M.D. | Deposit date: | 2022-08-10 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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2W23
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![BU of 2w23 by Molmil](/molmil-images/mine/2w23) | Structure of mutant W169Y of Pleurotus eryngii versatile peroxidase (VP) | Descriptor: | CALCIUM ION, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Ruiz-Duenas, F.J, Pogni, R, Morales, M, Giansanti, S, Mate, M.J, Romero, A, Martinez, M.J, Basosi, R, Martinez, A.T. | Deposit date: | 2008-10-23 | Release date: | 2009-01-20 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Protein Radicals in Fungal Versatile Peroxidase: Catalytic Tryptophan Radical in Both Compound I and Compound II and Studies on W164Y, W164H, and W164S Variants. J.Biol.Chem., 284, 2009
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8APT
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![BU of 8apt by Molmil](/molmil-images/mine/8apt) | Crystal Structure of H. influenzae TrmD in complex with Compound 13 | Descriptor: | 6-[[3-(aminomethyl)phenyl]methylamino]pyridine-3-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Hall, G, Cowan, R, Carr, M.D. | Deposit date: | 2022-08-10 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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8APV
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![BU of 8apv by Molmil](/molmil-images/mine/8apv) | Crystal Structure of H. influenzae TrmD in complex with Compound 27 | Descriptor: | 1-[[4-(aminomethyl)phenyl]methyl]pyrrolo[2,3-b]pyridine-5-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Hall, G, Cowan, R, Carr, M.D. | Deposit date: | 2022-08-10 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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8APW
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![BU of 8apw by Molmil](/molmil-images/mine/8apw) | Crystal Structure of H. influenzae TrmD in complex with Compound 30 | Descriptor: | 1-[2-oxidanylidene-2-(piperidin-4-ylamino)ethyl]pyrrolo[2,3-b]pyridine-5-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Hall, G, Cowan, R, Carr, M.D. | Deposit date: | 2022-08-10 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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8AIN
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![BU of 8ain by Molmil](/molmil-images/mine/8ain) | MCUGI SAUNG complex | Descriptor: | 1,2-ETHANEDIOL, MCUGI, SULFATE ION, ... | Authors: | Muselmani, W, Savva, R. | Deposit date: | 2022-07-26 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase. Viruses, 15, 2023
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8AIM
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![BU of 8aim by Molmil](/molmil-images/mine/8aim) | Ugi-2 SAUNG complex | Descriptor: | Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor | Authors: | Muselmani, W, Savva, R. | Deposit date: | 2022-07-26 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase. Viruses, 15, 2023
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8AIL
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![BU of 8ail by Molmil](/molmil-images/mine/8ail) | Bacillus phage VMY22 p56 in complex with Bacillus weidmannii Ung | Descriptor: | Bacillus phage VMY22 p56, GLYCEROL, IODIDE ION, ... | Authors: | Muselmani, W, Bagneris, C, Savva, R. | Deposit date: | 2022-07-26 | Release date: | 2023-06-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase. Viruses, 15, 2023
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3JXJ
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6YW0
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2VEV
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![BU of 2vev by Molmil](/molmil-images/mine/2vev) | CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B IN COMPLEX WITH AN ISOTHIAZOLIDINONE-CONTAINING INHIBITOR | Descriptor: | MAGNESIUM ION, N-[(1S)-1-(4-benzyl-1H-imidazol-2-yl)-2-{4-[(5S)-1,1-dioxido-3-oxoisothiazolidin-5-yl]phenyl}ethyl]-3-(trifluoromethyl)benzenesulfonamide, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1 | Authors: | Douty, B, Wayland, B, Ala, P.J, Bower, M.J, Pruitt, J, Bostrom, L, Wei, M, Klabe, R, Gonneville, L, Wynn, R, Burn, T.C, Liu, P.C.C, Combs, A.P, Yue, E.W. | Deposit date: | 2007-10-27 | Release date: | 2007-11-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Isothiazolidinone Inhibitors of Ptp1B Containing Imidazoles and Imidazolines Bioorg.Med.Chem.Lett., 18, 2008
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