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PDB: 27201 件

4A21
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Structure of Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase bound to sulfate
分子名称: FRUCTOSE-BISPHOSPHATE ALDOLASE, SODIUM ION, SULFATE ION
著者Coincon, M, De la Paz Santangelo, M, Gest, P.M, Guerin, M.E, Pham, H, Ryan, G, Puckett, S.E, Spencer, J.S, Gonzalez-Juarrero, M, Daher, R, Lenaerts, A.J, Schnappinger, D, Therisod, M, Ehrt, S, Jackson, M, Sygusch, J.
登録日2011-09-21
公開日2011-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Glycolytic and Non-Glycolytic Functions of the Fructose-1,6-Bisphosphate Aldolase of Mycobacterium Tuberculosis, an Essential Enzyme Produced by Replicating and Non-Replicating Bacilli
J.Biol.Chem., 286, 2011
4A22
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Structure of Mycobacterium tuberculosis fructose 1,6-bisphosphate aldolase bound to N-(4-hydroxybutyl)- glycolohydroxamic acid bis- phosphate
分子名称: 4-{hydroxy[(phosphonooxy)acetyl]amino}butyl dihydrogen phosphate, FRUCTOSE-BISPHOSPHATE ALDOLASE, SODIUM ION, ...
著者Coincon, M, De la Paz Santangelo, M, Gest, P.M, Guerin, M.E, Pham, H, Ryan, G, Puckett, S.E, Spencer, J.S, Gonzalez-Juarrero, M, Daher, R, Lenaerts, A.J, Schnappinger, D, Therisod, M, Ehrt, S, Jackson, M, Sygusch, J.
登録日2011-09-21
公開日2011-10-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.
J. Biol. Chem., 286, 2011
6ILO
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BU of 6ilo by Molmil
Cryo-EM structure of empty Echovirus 6 particle at PH 7.4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
著者Gao, G.F, Liu, S, Zhao, X, Peng, R.
登録日2018-10-19
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
4N2O
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Structure of a novel autonomous cohesin protein from Ruminococcus flavefaciens
分子名称: Autonomous cohesin, CHLORIDE ION
著者Frolow, F, Voronov-Goldman, M, Levy-Assaraf, M, Lamed, R, Bayer, E, Shimon, L.
登録日2013-10-05
公開日2013-12-18
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.442 Å)
主引用文献Structural characterization of a novel autonomous cohesin from Ruminococcus flavefaciens.
Acta Crystallogr F Struct Biol Commun, 70, 2014
1T2N
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Structure of a thermostable triple mutant of Bacillus subtilis lipase obtained through directed evolution
分子名称: Lipase, POTASSIUM ION
著者Rajakumara, E, Sankaranarayanan, R.
登録日2004-04-22
公開日2004-11-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase.
J.Mol.Biol., 341, 2004
6IRZ
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BU of 6irz by Molmil
Crystal structure of the zebrafish cap-specific adenosine methyltransferase bound to SAH and m7G-capped RNA
分子名称: 1,2-ETHANEDIOL, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, PDX1 C-terminal-inhibiting factor 1, ...
著者Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O.
登録日2018-11-15
公開日2018-12-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II-associated methyltransferase.
Science, 363, 2019
4AVH
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Structure of the FimH lectin domain in the trigonal space group, in complex with a thioalkyl alpha-D-mannoside at 2.1 A resolution
分子名称: 3-(propylsulfanyl)propyl alpha-D-mannopyranoside, FIMH, NICKEL (II) ION, ...
著者Wellens, A, Lahmann, M, Touaibia, M, Vaucher, J, Oscarson, S, Roy, R, Remaut, H, Bouckaert, J.
登録日2012-05-26
公開日2012-06-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh.
Biochemistry, 51, 2012
4AUP
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Tuber borchii Phospholipase A2
分子名称: ACETATE ION, PHOSPHOLIPASE A2 GROUP XIII, THIOCYANATE ION
著者Cavazzini, D, Meschi, F, Corsini, R, Bolchi, A, Rossi, G.-L, Einsle, O, Ottonello, S.
登録日2012-05-18
公開日2012-12-12
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Autoproteolytic Activation of a Symbiosis-Regulated Truffle Phospholipase A2
J.Biol.Chem., 288, 2013
4AV4
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FimH lectin domain co-crystal with a alpha-D-mannoside O-linked to a propynyl pyridine
分子名称: 3-(pyridin-3-yl)prop-2-yn-1-yl alpha-D-mannopyranoside, FIMH
著者Bouckaert, J, Touaibia, M, Roos, G, Shiao, T.C, Wang, Q, Papadopoulos, A, Roy, R.
登録日2012-05-23
公開日2012-06-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Tyrosine Gate as a Potential Entropic Lever in the Receptor-Binding Site of the Bacterial Adhesin Fimh.
Biochemistry, 51, 2012
6I47
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Structure of P. aeruginosa LpxC with compound 10: (2RS)-4-(5-(2-Fluoro-4-methoxyphenyl)-1-oxoisoindolin-2-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butanamide
分子名称: (2~{R})-4-[6-(2-fluoranyl-4-methoxy-phenyl)-3-oxidanylidene-1~{H}-isoindol-2-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide, (2~{S})-4-[6-(2-fluoranyl-4-methoxy-phenyl)-3-oxidanylidene-1~{H}-isoindol-2-yl]-2-methyl-2-methylsulfonyl-~{N}-oxidanyl-butanamide, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ...
著者Surivet, J.-P, Panchaud, P, Specklin, J.-L, Diethelm, S, Blumstein, A.-C, Gauvin, J.-C, Jacob, L, Masse, F, Mathieu, G, Mirre, A, Schmitt, C, Enderlin-Paput, M, Lange, R, Bur, D, Tidten-Luksch, N, Gnerre, C, Seeland, S, Hermann, C, Locher, H.H, Seiler, P, Mac Sweeney, A, Hubschwerlen, C, Ritz, D, Rueedi, G.
登録日2018-11-09
公開日2019-12-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria.
J.Med.Chem., 63, 2020
7JJO
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Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor
分子名称: Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Zhu, L, Zhang, Y, Paknejad, N, Dey, R, Huang, J, Lee, M.Y, Williams, D, Jordan, K.D, Eng, E.T, Ernst, O.P, Meyerson, J.R, Hite, R.K, Walz, T, Liu, W, Huang, X.Y.
登録日2020-07-27
公開日2020-09-02
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor.
Mol.Cell, 80, 2020
6JT8
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Crystal structure of 450-451_deletion mutant of FGAM Synthetase
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
著者Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R.
登録日2019-04-10
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation.
Sci Adv, 6, 2020
7JIY
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Structure of truncated zebrafish paragranulin
分子名称: Granulin 1
著者Takjoo, R, Daly, N.L.
登録日2020-07-23
公開日2020-08-26
実験手法SOLUTION NMR
主引用文献Folding of Truncated Granulin Peptides.
Biomolecules, 10, 2020
4AU9
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BU of 4au9 by Molmil
Crystal Structure of a Fungal DyP-Type Peroxidase from Auricularia auricula-judae
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Strittmatter, E, Pecyna, M, Ullrich, R, Hofrichter, M, Plattner, D.A, Liers, C, Piontek, K.
登録日2012-05-14
公開日2012-12-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献First Crystal Structure of a Fungal High-Redox Potential Dye-Decolorizing Peroxidase: Substrate Interaction Sites and Long-Range Electron Transfer.
J.Biol.Chem., 288, 2013
6K0S
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Catalytic domain of GH87 alpha-1,3-glucanase D1069A in complex with nigerose
分子名称: ACETIC ACID, Alpha-1,3-glucanase, CALCIUM ION, ...
著者Itoh, T, Intuy, R, Suyotha, W, Hayashi, J, Yano, S, Makabe, K, Wakayama, M, Hibi, T.
登録日2019-05-07
公開日2019-12-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.534 Å)
主引用文献Structural insights into substrate recognition and catalysis by glycoside hydrolase family 87 alpha-1,3-glucanase from Paenibacillus glycanilyticus FH11.
Febs J., 287, 2020
6KKV
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Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis
分子名称: DNA ligase A, N-[(4-methylphenyl)methyl]-1H-pyrrole-2-carboxamide, SULFATE ION
著者Ramachandran, R, Shukla, A, Afsar, M.
登録日2019-07-27
公開日2020-07-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A.
J.Struct.Biol., 213, 2021
6KLC
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Structure of apo Lassa virus polymerase
分子名称: MANGANESE (II) ION, RNA-directed RNA polymerase L
著者Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y.
登録日2019-07-30
公開日2020-03-18
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insight into arenavirus replication machinery.
Nature, 579, 2020
4APW
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Alp12 filament structure
分子名称: ALP12
著者Popp, D, Narita, A, Lee, L.J, Ghoshdastider, U, Xue, B, Srinivasan, R, Balasubramanian, M.K, Tanaka, T, Robinson, R.C.
登録日2012-04-06
公開日2012-05-16
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (19.700001 Å)
主引用文献Novel Actin-Like Filament Structure from Clostridium Tetani.
J.Biol.Chem., 287, 2012
419D
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OCTAMER 5'-R(*GP*UP*AP*UP*AP*CP*A)-D(P*C)-3' WITH SIX WATSON-CRICK BASE-PAIRS AND TWO 3' OVERHANG RESIDUES
分子名称: DNA/RNA (5'-R(*GP*UP*AP*UP*AP*CP*A)-D(P*C)-3')
著者Mitra, S.M, Shi, K, Biswas, R, Sundaralingam, M.
登録日1998-08-12
公開日2000-05-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of the octamer [r(guauaca)dC]2 with six Watson-Crick base-pairs and two 3' overhang residues.
J.Mol.Biol., 299, 2000
6JT7
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Crystal structure of 452-453_deletion mutant of FGAM Synthetase
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
著者Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R.
登録日2019-04-10
公開日2020-03-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation.
Sci Adv, 6, 2020
4A0F
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Structure of selenomethionine substituted bifunctional DAPA aminotransferase-dethiobiotin synthetase from Arabidopsis thaliana in its apo form.
分子名称: ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者Cobessi, D, Dumas, R, Pautre, V, Meinguet, C, Ferrer, J.L, Alban, C.
登録日2011-09-09
公開日2012-06-13
実験手法X-RAY DIFFRACTION (2.714 Å)
主引用文献Biochemical and Structural Characterization of the Arabidopsis Bifunctional Enzyme Dethiobiotin Synthetase-Diaminopelargonic Acid Aminotransferase: Evidence for Substrate Channeling in Biotin Synthesis.
Plant Cell, 24, 2012
6KB9
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X-ray structure of human PPARalpha ligand binding domain-pemafibrate co-crystals obtained by cross-seeding
分子名称: (2~{R})-2-[3-[[1,3-benzoxazol-2-yl-[3-(4-methoxyphenoxy)propyl]amino]methyl]phenoxy]butanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor alpha
著者Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I.
登録日2019-06-24
公開日2020-11-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.
Iscience, 23, 2020
4A7G
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Structure of human I113T SOD1 mutant complexed with 4-methylpiperazin- 1-yl)quinazoline in the p21 space group.
分子名称: 4-(4-METHYLPIPERAZIN-1-YL)QUINAZOLINE, ACETATE ION, COPPER (II) ION, ...
著者Wright, G.S.A, Kershaw, N.M, Sharma, R, Antonyuk, S.V, Strange, R.W, Berry, N.G, O'Neil, P.M, Hasnain, S.S.
登録日2011-11-14
公開日2012-10-24
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献X-ray crystallography and computational docking for the detection and development of protein-ligand interactions.
Curr.Med.Chem., 20, 2013
6KFZ
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SufS from Bacillus subtilis, soaked with L-cysteine for 90 sec at 1.96 angstrom resolution
分子名称: Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE
著者Nakamura, R, Takahashi, Y, Fujishiro, T.
登録日2019-07-09
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
Febs J., 287, 2020
1UWN
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The Initial Events in the Photocycle of Photoactive Yellow Protein: A Common Mechanism on Light Activation in Photoreceptor Proteins
分子名称: 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN, SULFATE ION
著者Kort, R, Hellingwerf, K.J, Ravelli, R.B.G.
登録日2004-02-10
公開日2004-03-25
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Initial events in the photocycle of photoactive yellow protein.
J. Biol. Chem., 279, 2004

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