7A5G
 
 | | Structure of the elongating human mitoribosome bound to mtEF-Tu.GMPPCP and A/T mt-tRNA | | 分子名称: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | | 著者 | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | | 登録日 | 2020-08-21 | | 公開日 | 2020-12-23 | | 実験手法 | ELECTRON MICROSCOPY (4.33 Å) | | 主引用文献 | Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
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2W2A
 | | Crystal Structure of p-coumaric Acid Decarboxylase from Lactobacillus plantarum: structural insights into the active site and decarboxylation catalytic mechanism | | 分子名称: | P-COUMARIC ACID DECARBOXYLASE | | 著者 | Rodriguez, H, Angulo, I, de las Rivas, B, Campillo, N, Paez, J.A, Munoz, R, Mancheno, J.M. | | 登録日 | 2008-10-27 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | P-Coumaric Acid Decarboxylase from Lactobacillus Plantarum: Structural Insights Into the Active Site and Decarboxylation Catalytic Mechanism.
Proteins, 78, 2010
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1CB7
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2WBD
 | | FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE-1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH AN AMP SITE INHIBITOR | | 分子名称: | FRUCTOSE-1,6-BISPHOSPHATASE 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-3-ethylbenzenesulfonamide | | 著者 | Ruf, A, Joseph, C, Benz, J, Fol, B, Tetaz, T, Kitas, E, Mohr, P, Kuhn, B, Wessel, H.P, Hebeisen, P, Haap, W, Huber, W, Alvarez Sanchez, R, Paehler, A, Bernadeau, A, Gubler, M, Schott, B, Tozzo, E. | | 登録日 | 2009-02-26 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Sulfonylureido Thiazoles as Fructose-1,6-Bisphosphatase Inhibitors for the Treatment of Type-2 Diabetes.
Bioorg.Med.Chem.Lett., 20, 2010
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2W9F
 | | Crystal Structure of CDK4 in complex with a D-type cyclin | | 分子名称: | CELL DIVISION PROTEIN KINASE 4, G1/S-SPECIFIC CYCLIN-D1 | | 著者 | Day, P.J, Cleasby, A, Tickle, I.J, Reilly, M.O, Coyle, J.E, Holding, F.P, McMenamin, R.L, Yon, J, Chopra, R, Lengauer, C, Jhoti, H. | | 登録日 | 2009-01-23 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal Structure of Human Cdk4 in Complex with a D-Type Cyclin.
Proc.Natl.Acad.Sci.USA, 106, 2009
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1CCW
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7BBU
 | | Crystal Structure of human Prolyl-tRNA synthetase in complex with NCP26 and L-Proline | | 分子名称: | 1,2-ETHANEDIOL, Bifunctional glutamate/proline--tRNA ligase, CHLORIDE ION, ... | | 著者 | Johansson, C, Tye, M, Payne, N.C, Mazitschek, R, Krojer, T, Oppermann, U.C.T. | | 登録日 | 2020-12-18 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal Structure of human Prolyl-tRNA synthetase in complex with NCP26 and L-Proline
To Be Published
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2WD0
 | | CRYSTAL STRUCTURE OF NONSYNDROMIC DEAFNESS (DFNB12) ASSOCIATED MUTANT D124G OF MOUSE CADHERIN-23 EC1-2 | | 分子名称: | CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | | 登録日 | 2009-03-18 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Structural Determinants of Cadherin-23 Function in Hearing and Deafness.
Neuron, 66, 2010
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7X63
 | | SARS-CoV-2-Beta-RBD and BD-236-GWP/P-VK antibody complex | | 分子名称: | BD-236 Fab heavy chain, BD-236 Fab light chain, Spike protein S1 | | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | 登録日 | 2022-03-06 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | SARS-CoV-2-Beta-RBD and BD-236-GWP/P-VK antibody complex
To Be Published
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2VNL
 | | MUTANT Y108Wdel OF THE HEADBINDING DOMAIN OF PHAGE P22 TAILSPIKE C- TERMINally fused to ISOLEUCINE ZIPPER pIIGCN4 (chimera II) | | 分子名称: | BIFUNCTIONAL TAIL PROTEIN, PIIGCN4, GLYCEROL | | 著者 | Mueller, J.J, Seul, A, Mueller, G, Seckler, R, Heinemann, U. | | 登録日 | 2008-02-05 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker
Acta Crystallogr.,Sect.D, 70, 2014
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7X66
 | | SARS-CoV-2-Omicron-RBD and BD-236-GWP/P-VK antibody complex | | 分子名称: | BD-236 Fab heavy chain, BD-236 Fab light chain, Spike protein S1 | | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | 登録日 | 2022-03-06 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | SARS-CoV-2-Omicron-RBD and BD-236-GWP/P-VK antibody complex
To Be Published
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2VVV
 | | Aminopyrrolidine-related triazole Factor Xa inhibitor | | 分子名称: | 5-chloro-N-[1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)-1H-1,2,4-triazol-3-yl]thiophene-2-carboxamide, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | | 著者 | Groebke-Zbinden, K, Banner, D.W, Benz, J.M, Blasco, F, Decoret, G, Himber, J, Kuhn, B, Panday, N, Ricklin, F, Risch, P, Schlatter, D, Stahl, M, Unger, R, Haap, W. | | 登録日 | 2008-06-12 | | 公開日 | 2009-07-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit.
Eur.J.Med.Chem., 44, 2009
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7XIK
 | | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex | | 分子名称: | B38 Fab heavy chain, B38 Fab light chain, Spike protein S1 | | 著者 | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | 登録日 | 2022-04-13 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex
To Be Published
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2VOV
 | | An oxidized tryptophan facilitates copper-binding in Methylococcus capsulatus secreted protein MopE. The structure of wild-type MopE to 1.35AA | | 分子名称: | CALCIUM ION, COPPER (II) ION, SURFACE-ASSOCIATED PROTEIN | | 著者 | Helland, R, Fjellbirkeland, A, Karlsen, O.A, Ve, T, Lillehaug, J.R, Jensen, H.B. | | 登録日 | 2008-02-22 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | An Oxidized Tryptophan Facilitates Copper Binding in Methylococcus Capsulatus-Secreted Protein Mope.
J.Biol.Chem., 283, 2008
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7XK9
 | | Structure of human beta2 adrenergic receptor bound to constrained isoproterenol | | 分子名称: | (5R,6R)-6-(propan-2-ylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Camelid Antibody Fragment, Endolysin,Beta-2 adrenergic receptor, ... | | 著者 | Xu, X, Shonberg, J, Kaindl, J, Clark, M, Stobel, A, Maul, L, Mayer, D, Hubner, H, Venkatakrishnan, A, Dror, R, Kobilka, B.K, Sunahara, R, Liu, X, Gmeiner, P. | | 登録日 | 2022-04-19 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Constrained catecholamines gain beta 2 AR selectivity through allosteric effects on pocket dynamics.
Nat Commun, 14, 2023
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7XLY
 | | Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis | | 分子名称: | Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION | | 著者 | Singh, R, Kundu, P, Singh, B.K, Bhattacharyya, S, Das, A.K. | | 登録日 | 2022-04-23 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties.
Febs J., 290, 2023
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7XJF
 | | Crystal structure of 6MW3211 Fab in complex with CD47 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M. | | 登録日 | 2022-04-16 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment.
Theranostics, 13, 2023
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2WLQ
 | | Nucleophile-disabled Lam16A mutant holds laminariheptaose (L7) in a cyclical conformation | | 分子名称: | PUTATIVE LAMINARINASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose | | 著者 | Vasur, J, Kawai, R, Andersson, E, Widmalm, G, Jonsson, K.H, Hansson, H, Engstrom, A, Igarashi, K, Sandgren, M, Samejima, M, Stahlberg, J. | | 登録日 | 2009-06-24 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Synthesis of Cyclic Beta-Glucan Using Laminarinase 16A Glycosynthase Mutant from the Basidiomycete Phanerochaete Chrysosporium.
J.Am.Chem.Soc., 132, 2010
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2XAQ
 | | Crystal structure of LSD1-CoREST in complex with a tranylcypromine derivative (MC2584, 13b) | | 分子名称: | 3-{4-[(PHENYLCARBONYL)AMINO]PHENYL}PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ... | | 著者 | Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A. | | 登録日 | 2010-03-31 | | 公開日 | 2010-05-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
J.Am.Chem.Soc., 132, 2010
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2WQM
 | | Structure of apo human Nek7 | | 分子名称: | NICKEL (II) ION, SERINE/THREONINE-PROTEIN KINASE NEK7, SULFATE ION | | 著者 | Richards, M.W, Bayliss, R. | | 登録日 | 2009-08-24 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An Auto-Inhibitory Tyrosine Motif in the Cell-Cycle Regulated Nek7 Kinase is Released Through Binding of Nek9
Mol.Cell, 36, 2009
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7X3Y
 | | Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3) | | 分子名称: | 9A3 heavy chain, 9A3 light chain, VP2, ... | | 著者 | Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N. | | 登録日 | 2022-03-01 | | 公開日 | 2023-06-07 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)
To Be Published
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2WUQ
 | | Crystal structure of BlaB protein from Streptomyces cacaoi | | 分子名称: | BETA-LACTAMASE REGULATORY PROTEIN BLAB, GLYCEROL | | 著者 | Dandois, S, Herman, R, Sauvage, E, Charlier, P, Joris, B, Kerff, F. | | 登録日 | 2009-10-07 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Crystal Structure of Blab Protein from Streptomyces Cacaoi
To be Published
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2X01
 | | CRYSTAL STRUCTURE OF THE OXA-10 S67A MUTANT AT PH 7 | | 分子名称: | BETA-LACTAMASE OXA-10, DIMETHYL SULFOXIDE, SULFATE ION, ... | | 著者 | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Galleni, M, Charlier, P. | | 登録日 | 2009-12-04 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Evidence of Chloride Inhibition and Impact of the Hydrophobic Core on the Lysine Carboxylated in Class D Beta-Lactamase
To be Published
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2WVW
 | | Cryo-EM structure of the RbcL-RbcX complex | | 分子名称: | RBCX PROTEIN, RIBULOSE BISPHOSPHATE CARBOXYLASE LARGE CHAIN | | 著者 | Liu, C, Young, A.L, Starling-Windhof, A, Bracher, A, Saschenbrecker, S, Rao, B.V, Rao, K.V, Berninghausen, O, Mielke, T, Hartl, F.U, Beckmann, R, Hayer-Hartl, M. | | 登録日 | 2009-10-20 | | 公開日 | 2010-01-19 | | 最終更新日 | 2019-10-23 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Coupled Chaperone Action in Folding and Assembly of Hexadecameric Rubisco
Nature, 463, 2010
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7XAQ
 | | Cryo-EM structure of PvrA-DNA complex | | 分子名称: | Probable transcriptional regulator, fadD1 | | 著者 | Zhu, Y.B, Su, Z.M, Bao, R. | | 登録日 | 2022-03-18 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | The Pseudomonas aeruginosa regulator PvrA binds cooperatively to multiple pseudo-palindromic sites to efficiently stimulate target gene
To be published
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