7XLY

Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis

Summary for 7XLY

Entry DOI	10.2210/pdb7xly/pdb
Descriptor	Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION (2 entities in total)
Functional Keywords	acetyl-coa acetyltransferase, fatty acid metabolism, mycobacterium tuberculosis, transferase
Biological source	Mycobacterium tuberculosis H37Rv
Total number of polymer chains	4
Total formula weight	184796.55
Authors	Singh, R.,Kundu, P.,Singh, B.K.,Bhattacharyya, S.,Das, A.K. (deposition date: 2022-04-23, release date: 2023-04-26, Last modification date: 2023-08-30)
Primary citation	Singh, R.,Kundu, P.,Mishra, V.K.,Singh, B.K.,Bhattacharyya, S.,Das, A.K. Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties. Febs J., 290:3997-4022, 2023 Cited by PubMed: 37026388 DOI: 10.1111/febs.16792 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation