7BBU

Crystal Structure of human Prolyl-tRNA synthetase in complex with NCP26 and L-Proline

Summary for 7BBU

• Entry DOI: 10.2210/pdb7bbu/pdb
• Descriptor: Bifunctional glutamate/proline--tRNA ligase, PROLINE, ~{N}-(2,3-dihydro-1~{H}-inden-2-yl)-3-(piperidin-1-ylcarbonylamino)pyrazine-2-carboxamide, ... (8 entities in total)
• Functional Keywords: inhibitor, ligase, protein biosynthesis, atp binding, trna
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 59656.83

Authors

Johansson, C.,Tye, M.,Payne, N.C.,Mazitschek, R.,Krojer, T.,Oppermann, U.C.T. (deposition date: 2020-12-18, release date: 2022-01-12, Last modification date: 2024-01-31)

• Primary citation: Johansson, C.,Tye, M.,Payne, N.C.,Mazitschek, R.,Krojer, T.,Oppermann, U.C.T.; Crystal Structure of human Prolyl-tRNA synthetase in complex with NCP26 and L-Proline; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.19 Å)