2OQ5
 
 | | Crystal structure of DESC1, a new member of the type II transmembrane serine proteinases family | | 分子名称: | BENZAMIDINE, Transmembrane protease, serine 11E | | 著者 | Kyrieleis, O.J.P, Huber, R, Madison, E.L, Jacob, U. | | 登録日 | 2007-01-31 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.
Febs J., 274, 2007
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4RZR
 | | Bypass of a bulky adduct dG1,8 by DPO4 | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | 著者 | Vyas, R, Suo, Z. | | 登録日 | 2014-12-23 | | 公開日 | 2015-09-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mechanistic Basis for the Bypass of a Bulky DNA Adduct Catalyzed by a Y-Family DNA Polymerase.
J.Am.Chem.Soc., 137, 2015
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3RM7
 | | CDK2 in complex with inhibitor KVR-1-91 | | 分子名称: | 1,2-ETHANEDIOL, 2-[(4-hydroxybenzyl)amino]-5-nitrobenzamide, Cyclin-dependent kinase 2 | | 著者 | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | | 登録日 | 2011-04-20 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening
To be Published
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4TMT
 | | Translation initiation factor eIF5B (517-858) mutant D533A from C. thermophilum, bound to GTPgammaS | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ... | | 著者 | Kuhle, B, Ficner, R. | | 登録日 | 2014-06-02 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
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5LH1
 | | Low dose Thaumatin - 360-400 ms. | | 分子名称: | L(+)-TARTARIC ACID, Thaumatin-1 | | 著者 | Schubert, R, Kapis, S, Heymann, M, Giquel, Y, Bourenkov, G, Schneider, T, Betzel, C, Perbandt, M. | | 登録日 | 2016-07-08 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution.
IUCrJ, 3, 2016
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4TOD
 | | 2.05A resolution structure of BfrB (D34F) from Pseudomonas aeruginosa | | 分子名称: | Bacterioferritin, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Lovell, S, Battaile, K.P, Yao, H, Kumar, R, Eshelman, K, Rivera, M. | | 登録日 | 2014-06-05 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic.
Biochemistry, 54, 2015
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5LIJ
 | | polyalanine chain built in bacteriophage phi812K1-420 cement protein density map | | 分子名称: | polyalanine chain built in bacteriophage phi812K1-420 cement protein density map | | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | | 登録日 | 2016-07-14 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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5B2R
 | | Crystal structure of the Streptococcus pyogenes Cas9 VQR variant in complex with sgRNA and target DNA (TGA PAM) | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | | 著者 | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | | 登録日 | 2016-02-02 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Mol.Cell, 61, 2016
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4TPR
 | | Structure of Tau5 antibody Fab fragment | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol, CHLORIDE ION, ... | | 著者 | Cehlar, O, Skrabana, R, Novak, M. | | 登録日 | 2014-06-09 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of Tau5 antibody Fab fragment
To Be Published
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5B3J
 | | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil | | 分子名称: | Fab, heavy chain, light chain, ... | | 著者 | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | 登録日 | 2016-03-01 | | 公開日 | 2016-05-11 | | 最終更新日 | 2022-03-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Nature, 534, 2016
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4TMX
 | | Translation initiation factor eIF5B (517-858) mutant D533N from C. thermophilum, bound to GTP and sodium | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Kuhle, B, Ficner, R. | | 登録日 | 2014-06-02 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Embo J., 33, 2014
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4TOA
 | | 1.95A resolution structure of Iron Bound BfrB (N148L) from Pseudomonas aeruginosa | | 分子名称: | Bacterioferritin, FE (II) ION, POTASSIUM ION, ... | | 著者 | Lovell, S, Battaile, K.P, Yao, H, Kumar, R, Eshelman, K, Rivera, M. | | 登録日 | 2014-06-05 | | 公開日 | 2015-02-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Concerted motions networking pores and distant ferroxidase centers enable bacterioferritin function and iron traffic.
Biochemistry, 54, 2015
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4TQ2
 | | Structure of S-type Phycobiliprotein Lyase CPES from Guillardia theta | | 分子名称: | HEXANE-1,6-DIOL, Putative phycoerythrin lyase | | 著者 | Gasper, R, Overkamp, K.E, Frankenberg-Dinkel, N, Hofmann, E. | | 登録日 | 2014-06-10 | | 公開日 | 2014-08-13 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Insights into the Biosynthesis and Assembly of Cryptophycean Phycobiliproteins.
J.Biol.Chem., 289, 2014
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4TSD
 | | Crystal structure of Helicobacter pylori HP1029 | | 分子名称: | 1,2-ETHANEDIOL, HP1029, ZINC ION | | 著者 | Vallese, F, Percudani, R, Zanotti, G. | | 登録日 | 2014-06-18 | | 公開日 | 2015-06-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The crystal structure of Helicobacter pylori HP1029 highlights the functional diversity of the sialic acid-related DUF386 family.
Febs J., 282, 2015
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5LXQ
 | | Structure of PRL-1 in complex with the Bateman domain of CNNM2 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Metal transporter CNNM2, Protein tyrosine phosphatase type IVA 1, ... | | 著者 | GIMENEZ-Mascarell, P, Oyenarte, I, Hardy, S, Breiderhoff, T, Stuiver, M, Kostantin, E, Diercks, T, Pey, A.L, Ereno-ORBEA, J, Martinez-Chantar, M.L, Khalaf-Nazzal, R, Claverie-Martin, F, Muller, D, Tremblay, M, Martinez-Cruz, L.A. | | 登録日 | 2016-09-22 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.335 Å) | | 主引用文献 | Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
J. Biol. Chem., 292, 2017
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5AP0
 | | Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. | | 分子名称: | 1,2-ETHANEDIOL, 9-CYCLOPENTYL-2-[[2-METHOXY-4-[(1-METHYLPIPERIDIN-4-YL)OXY]-PHENYL]AMINO]-7-METHYL-7,9-DIHYDRO-8H-PURIN-8-ONE, DIMETHYL SULFOXIDE, ... | | 著者 | Gurden, M.D, Westwood, I.M, Faisal, A, Naud, S, Cheung, K.J, McAndrew, C, Wood, A, Schmitt, J, Boxall, K, Mak, G, Workman, P, Burke, R, Hoelder, S, Blagg, J, van Montfort, R.L.M, Linardopoulos, S. | | 登録日 | 2015-09-14 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Naturally Occurring Mutations in the Mps1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance.
Cancer Res., 75, 2015
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5LL3
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5BN2
 | | Room Temperature Structure of Pichia pastoris aquaporin at 1.3 A | | 分子名称: | AQY1 protein, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Fischer, G, Kosinska Eriksson, U, Hedfalk, K, Neutze, R. | | 登録日 | 2015-05-25 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Room Temperature Structure of Pichia pastoris aquaporin at 1.3 A
To Be Published
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5LZF
 | | Structure of the 70S ribosome with fMetSec-tRNASec in the hybrid pre-translocation state (H) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H. | | 登録日 | 2016-09-29 | | 公開日 | 2016-11-23 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
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4RPY
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4RR3
 | | Crystal structure of a recombinant EV71 virus particle | | 分子名称: | Capsid protein VP0, Capsid protein VP1, Capsid protein VP3 | | 著者 | Chen, R, Lyu, K. | | 登録日 | 2014-11-06 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.103 Å) | | 主引用文献 | Crystal structures of enterovirus 71 (EV71) recombinant virus particles provide insights into vaccine design.
J.Biol.Chem., 290, 2015
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4U0R
 | | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4 | | 分子名称: | Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, Reticulocyte binding protein 5 | | 著者 | Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. | | 登録日 | 2014-07-14 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.
Nature, 515, 2014
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4U17
 | | Swapped dimer of the human Fyn-SH2 domain | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Tyrosine-protein kinase Fyn | | 著者 | Garcia-Pino, A, Huculeci, R, Lenaerts, T, van Nuland, N.A.J. | | 登録日 | 2014-07-15 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Swapped dimer of the human Fyn-SH2 domain
To Be Published
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5M3L
 | | Single-particle cryo-EM using alignment by classification (ABC): the structure of Lumbricus terrestris hemoglobin | | 分子名称: | Extracellular globin-2, Extracellular globin-3, Extracellular globin-4, ... | | 著者 | Afanasyev, P, Linnemayr-Seer, C, Ravelli, R.B.G, Matadeen, R, De Carlo, S, Alewijnse, B, Portugal, R.V, Pannu, N.S, Schatz, M, van Heel, M. | | 登録日 | 2016-10-15 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Single-particle cryo-EM using alignment by classification (ABC): the structure of Lumbricus terrestris haemoglobin.
IUCrJ, 4, 2017
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4U7W
 | | The crystal structure of the terminal R domain from the myxalamid PKS-NRPS biosynthetic pathway | | 分子名称: | ACETATE ION, MxaA, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Tsai, S.C, Keasling, J.D, Luo, R, Barajas, J.F, Phelan, R.M, Schaub, A.J, Kliewer, J. | | 登録日 | 2014-07-31 | | 公開日 | 2015-08-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | | 主引用文献 | Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols.
Chem.Biol., 22, 2015
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