Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 27201 件

6BBS
DownloadVisualize
BU of 6bbs by Molmil
Joint X-ray/neutron structure of human carbonic anhydrase II in complex with brinzolamide
分子名称: (+)-4-ETHYLAMINO-3,4-DIHYDRO-2-(METHOXY)PROPYL-2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE-1,1-DIOXIDE, Carbonic anhydrase 2, ZINC ION
著者Kovalevsky, A, Aggarwal, M, McKenna, R.
登録日2017-10-19
公開日2018-02-28
最終更新日2024-03-13
実験手法NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
主引用文献"To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation.
Structure, 26, 2018
2KQ2
DownloadVisualize
BU of 2kq2 by Molmil
Solution NMR structure of the apo form of a ribonuclease H domain of protein DSY1790 from Desulfitobacterium hafniense, Northeast Structural Genomics target DhR1A
分子名称: Ribonuclease H-related protein
著者Mills, J.L, Eletsky, A, Hua, J, Belote, R.L, Buchwald, W.A, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2009-10-24
公開日2010-03-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the apo form of a ribonuclease H domain of protein DSY1790 from Desulfitobacterium hafniense, Northeast Structural Genomics target DhR1A
To be Published
6B03
DownloadVisualize
BU of 6b03 by Molmil
The crystal structure of the ferredoxin protease FusC in complex with its substrate plant ferredoxin
分子名称: Ferredoxin-2, chloroplastic, Putative zinc protease
著者Grinter, R.
登録日2017-09-13
公開日2018-06-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants.
PLoS Biol., 16, 2018
3C49
DownloadVisualize
BU of 3c49 by Molmil
Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor KU0058948
分子名称: 4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one, Poly(ADP-ribose) polymerase 3
著者Lehtio, L, Karlberg, T, Arrowsmith, C.H, Berglund, H, Bountra, C, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Helleday, T, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Welin, M, Weigelt, J, Structural Genomics Consortium (SGC)
登録日2008-01-29
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
J.Med.Chem., 52, 2009
3C4H
DownloadVisualize
BU of 3c4h by Molmil
Human poly(ADP-ribose) polymerase 3, catalytic fragment in complex with an inhibitor DR2313
分子名称: 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Poly(ADP-ribose) polymerase 3
著者Lehtio, L, Collins, R, Arrowsmith, C.H, Berglund, H, Bountra, C, Busam, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Herman, M.D, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Svensson, L, Thorsell, A.G, Tresaugues, L, Van den Berg, S, Welin, M, Weigelt, J, Structural Genomics Consortium (SGC)
登録日2008-01-30
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
J.Med.Chem., 52, 2009
4FCR
DownloadVisualize
BU of 4fcr by Molmil
Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization
分子名称: 2-{[4-(2-chloro-4,5-dimethoxyphenyl)-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-2-yl]sulfanyl}-N,N-dimethylacetamide, Heat shock protein HSP 90-alpha
著者Davies, N.G, Browne, H, Davis, B, Foloppe, N, Geoffrey, S, Gibbons, B, Hart, T, Drysdale, M.J, Mansell, H, Massey, A, Matassova, N, Moore, J.D, Murray, J, Pratt, R, Ray, S, Roughley, S.D, Jensen, M.R, Schoepfer, J, Scriven, K, Simmonite, H, Stokes, S, Surgenor, A, Webb, P, Wright, L, Brough, P.
登録日2012-05-25
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization.
Bioorg.Med.Chem., 20, 2012
3GUW
DownloadVisualize
BU of 3guw by Molmil
Crystal Structure of the TatD-like Protein (AF1765) from Archaeoglobus fulgidus, Northeast Structural Genomics Consortium Target GR121
分子名称: ZINC ION, uncharacterized protein AF_1765
著者Forouhar, F, Su, M, Seetharaman, J, Fang, F, Xiao, R, Cunningham, K, Ma, L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2009-03-30
公開日2009-04-07
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Northeast Structural Genomics Consortium Target GR121
To be Published
2KRT
DownloadVisualize
BU of 2krt by Molmil
Solution NMR Structure of a Conserved Hypothetical Membrane Lipoprotein Obtained from Ureaplasma parvum: Northeast Structural Genomics Consortium Target UuR17A (139-239)
分子名称: Conserved hypothetical membrane lipoprotein
著者Mani, R, Swapna, G, Janjua, H, Ciccosanti, C, Huang, Y, Patel, D, Xiao, R, Acton, T, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2009-12-22
公開日2010-01-05
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of a Conserved Hypothetical Membrane Lipoprotein obtained from Ureaplasma parvum : Northeast Structural Genomics Consortium Target UuR17A (139-239)
To be Published
3GYG
DownloadVisualize
BU of 3gyg by Molmil
Crystal structure of yhjK (haloacid dehalogenase-like hydrolase protein) from Bacillus subtilis
分子名称: MAGNESIUM ION, NTD biosynthesis operon putative hydrolase ntdB
著者Nocek, B, Stein, A, Wu, R, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-04-03
公開日2009-05-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of yhjK (haloacid dehalogenase-like hydrolase protein) from Bacillus subtilis
To be Published
4OO7
DownloadVisualize
BU of 4oo7 by Molmil
THE 1.55A CRYSTAL STRUCTURE of NAF1 (MINER1): THE REDOX-ACTIVE 2FE-2S PROTEIN
分子名称: CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
著者Tamir, S, Eisenberg-Domovich, Y, Colman, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Jenning, P.A, Livnah, O, Nechushtai, R.
登録日2014-01-31
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Acta Crystallogr.,Sect.D, 70, 2014
4OOK
DownloadVisualize
BU of 4ook by Molmil
Third Metal bound M.tuberculosis methionine aminopeptidase
分子名称: COBALT (II) ION, Methionine aminopeptidase 2, SODIUM ION
著者Reddi, R, Addlagatta, A.
登録日2014-02-03
公開日2015-02-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
6DPU
DownloadVisualize
BU of 6dpu by Molmil
Undecorated GMPCPP microtubule
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Zhang, R, Nogales, E.
登録日2018-06-09
公開日2018-07-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Separating the effects of nucleotide and EB binding on microtubule structure.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DR8
DownloadVisualize
BU of 6dr8 by Molmil
Metallo-beta-lactamase from Cronobacter sakazakii (Enterobacter sakazakii) HARLDQ motif mutant S60/R118H/Q121H/K254H
分子名称: (2-hydroxyethoxy)acetaldehyde, Beta-lactamase, PHOSPHATE ION, ...
著者Monteiro Pedroso, M, Waite, D, Natasa, M, McGeary, R, Guddat, L, Hugenholtz, P, Schenk, G.
登録日2018-06-11
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.476 Å)
主引用文献Broad spectrum antibiotic-degrading metallo-beta-lactamases are phylogenetically diverse
Protein Cell, 2020
6D9W
DownloadVisualize
BU of 6d9w by Molmil
Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter, in the inward-open apo state
分子名称: Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain, ...
著者Gaudet, R, Bane, L.B, Weihofen, W.A, Singharoy, A, Zimanyi, C.M, Bozzi, A.T.
登録日2018-04-30
公開日2019-02-13
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.941 Å)
主引用文献Structures in multiple conformations reveal distinct transition metal and proton pathways in an Nramp transporter.
Elife, 8, 2019
6D66
DownloadVisualize
BU of 6d66 by Molmil
Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16
分子名称: 1,2-ETHANEDIOL, D-ALANINE, DI(HYDROXYETHYL)ETHER, ...
著者Gumpena, R, Waugh, D.S, Lountos, G.T.
登録日2018-04-20
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.226 Å)
主引用文献MBP-binding DARPins facilitate the crystallization of an MBP fusion protein.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6DFU
DownloadVisualize
BU of 6dfu by Molmil
Tryptophan--tRNA ligase from Haemophilus influenzae.
分子名称: TRYPTOPHAN, Tryptophan--tRNA ligase
著者Osipiuk, J, Maltseva, N, Mulligan, R, Grimshaw, S, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-05-15
公開日2018-05-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Tryptophan--tRNA ligase from Haemophilus influenzae.
to be published
4LVK
DownloadVisualize
BU of 4lvk by Molmil
MobM Relaxase Domain (MOBV; Mob_Pre) bound to plasmid pMV158 oriT DNA (22nt+3'Phosphate). Mn-bound crystal structure at pH 4.6
分子名称: ACTTTAT oligonucleotide, ATAAAGTATAGTGTGpo oligonucleotide, MANGANESE (II) ION, ...
著者Pluta, R, Boer, D.R, Coll, M.
登録日2013-07-26
公開日2014-09-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural basis of a histidine-DNA nicking/joining mechanism for gene transfer and promiscuous spread of antibiotic resistance.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6C6T
DownloadVisualize
BU of 6c6t by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound with RfaH
分子名称: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A.
登録日2018-01-19
公開日2018-07-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators.
Cell, 173, 2018
6CAA
DownloadVisualize
BU of 6caa by Molmil
CryoEM structure of human SLC4A4 sodium-coupled acid-base transporter NBCe1
分子名称: Electrogenic sodium bicarbonate cotransporter 1
著者Huynh, K.W, Jiang, J, Abuladze, N, Tsirulnikov, K, Kao, L, Shao, X, Newman, D, Azimov, R, Pushkin, A, Zhou, Z.H, Kurtz, I.
登録日2018-01-29
公開日2018-03-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.
Nat Commun, 9, 2018
6BPO
DownloadVisualize
BU of 6bpo by Molmil
The crystal structure of the Ferric-Catecholate import receptor Fiu from K12 E. coli: Closed form (P1)
分子名称: Catecholate siderophore receptor Fiu, octyl beta-D-glucopyranoside
著者Grinter, R.
登録日2017-11-23
公開日2018-11-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structure of the bacterial iron-catecholate transporter Fiu suggests that it imports substrates via a two-step mechanism.
J.Biol.Chem., 2019
6BSQ
DownloadVisualize
BU of 6bsq by Molmil
Enterococcus faecalis Penicillin Binding Protein 4 (PBP4)
分子名称: CHLORIDE ION, GLYCEROL, PBP4 protein
著者Moon, T.M, D'Andrea, E.D, Peti, W, Page, R.
登録日2017-12-04
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
3E29
DownloadVisualize
BU of 3e29 by Molmil
X-Ray structure of the protein Q7WE92_BORBR from thioesterase superfamily. Northeast Structural Genomics Consortium Target BoR214A.
分子名称: uncharacterized protein Q7WE92_BORBR
著者Kuzin, A.P, Chen, Y, Setharaman, J, Wang, D, Mao, L, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG)
登録日2008-08-05
公開日2008-09-30
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-Ray structure of the protein Q7WE92_BORBR from thioesterase superfamily. Northeast Structural Genomics Consortium Target BoR214A.
To be Published
6BVD
DownloadVisualize
BU of 6bvd by Molmil
Structure of Botulinum Neurotoxin Serotype HA Light Chain
分子名称: ACETATE ION, CALCIUM ION, Light Chain, ...
著者Jin, R, Lam, K.
登録日2017-12-12
公開日2018-05-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural and biochemical characterization of the protease domain of the mosaic botulinum neurotoxin type HA.
Pathog Dis, 76, 2018
2Q2M
DownloadVisualize
BU of 2q2m by Molmil
Beta-lactoglobulin (native)
分子名称: Beta-lactoglobulin
著者Vijayalakshmi, L, Krishna, R, Sankaranarayanan, R, Vijayan, M.
登録日2007-05-29
公開日2008-02-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献An asymmetric dimer of beta-lactoglobulin in a low humidity crystal form-Structural changes that accompany partial dehydration and protein action.
Proteins, 71, 2007
6DDQ
DownloadVisualize
BU of 6ddq by Molmil
Crystal structure of the double mutant (R39Q/D52N) of the full-length NT5C2 in the basal state
分子名称: 1,2-ETHANEDIOL, Cytosolic purine 5'-nucleotidase, PHOSPHATE ION
著者Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L.
登録日2018-05-10
公開日2018-07-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia.
Cancer Cell, 34, 2018

222624

件を2024-07-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon