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PDB: 39 件
5I4T
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BU of 5i4t by Molmil
Immature hexagonal lattice of HIV-1 Gag
分子名称: CTD-SP1 fragment of HIV-1 Gag
著者Pornillos, O, Wagner, J.M, Zadrozny, K, Ganser-Pornillos, B.K.
登録日2016-02-12
公開日2016-07-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.273 Å)
主引用文献Crystal structure of an HIV assembly and maturation switch.
Elife, 5, 2016
5VZW
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BU of 5vzw by Molmil
TRIM23 RING domain in complex with UbcH5-Ub
分子名称: E3 ubiquitin-protein ligase TRIM23, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Pornillos, O, Dawidziak, D.
登録日2017-05-29
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.278 Å)
主引用文献Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.
Proteins, 85, 2017
3MGE
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BU of 3mge by Molmil
X-ray Structure of Hexameric HIV-1 CA
分子名称: 1,2-ETHANEDIOL, Capsid protein p24
著者Pornillos, O.
登録日2010-04-05
公開日2010-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Disulfide Bond Stabilization of the Hexameric Capsomer of Human Immunodeficiency Virus.
J.Mol.Biol., 401, 2010
7URN
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BU of 7urn by Molmil
Structure of HIV-1 capsid declination
分子名称: HIV-1 capsid protein, INOSITOL HEXAKISPHOSPHATE
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
登録日2022-04-22
公開日2023-02-15
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
7URT
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BU of 7urt by Molmil
T=1 particle HIV-1 CA G60A/G61P/M66A
分子名称: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
登録日2022-04-22
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
8EET
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BU of 8eet by Molmil
T=1 particle HIV-1 CA M66A
分子名称: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
登録日2022-09-07
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
8EEP
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BU of 8eep by Molmil
T=1 particle HIV-1 CA G60A/G61P
分子名称: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
登録日2022-09-07
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
8EJL
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BU of 8ejl by Molmil
Structure of HIV-1 capsid declination in complex with CPSF6-FG peptide
分子名称: Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T, dos Santos, N.F.B.
登録日2022-09-17
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
4QNB
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BU of 4qnb by Molmil
Disulfide stabilized HIV-1 CA hexamer in complex with PHENYL-L-PHENYLALANINAMIDE inhibitor
分子名称: CAPSID PROTEIN P24, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
著者Pornillos, O.
登録日2014-06-17
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
7TGQ
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BU of 7tgq by Molmil
Zinc finger antiviral protein (ZAP) central domain bound to ADP-ribose
分子名称: ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, ZINC ION, ...
著者Pornillos, O.P.
登録日2022-01-09
公開日2022-02-02
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Poly(ADP-ribose) potentiates ZAP antiviral activity.
Plos Pathog., 18, 2022
5TEO
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BU of 5teo by Molmil
Dimer of HIV-1 Gag CTD-SP1 fragment
分子名称: HIV-1 Gag CTD-SP1
著者Pornillos, O, Wagner, J.M, Zadrozny, K.K, Ganser-Pornillos, B.K.
登録日2016-09-22
公開日2017-09-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.046 Å)
主引用文献To be published
To Be Published
3P0A
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BU of 3p0a by Molmil
X-ray structure of pentameric HIV-1 CA
分子名称: HIV-1 CA
著者Pornillos, O.
登録日2010-09-27
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (5.954 Å)
主引用文献Atomic-level modelling of the HIV capsid.
Nature, 469, 2011
3P05
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BU of 3p05 by Molmil
X-ray structure of pentameric HIV-1 CA
分子名称: HIV-1 CA, IODIDE ION
著者Pornillos, O.
登録日2010-09-27
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Atomic-level modelling of the HIV capsid.
Nature, 469, 2011
7KZH
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BU of 7kzh by Molmil
Zinc finger antiviral protein (ZAP) central domain
分子名称: ZINC ION, Zinc finger CCCH-type antiviral protein 1
著者Pornillos, O.P.
登録日2020-12-10
公開日2021-12-15
最終更新日2023-01-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Poly(ADP-ribose) potentiates ZAP antiviral activity.
Plos Pathog., 18, 2022
4LTB
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BU of 4ltb by Molmil
Coiled-coil domain of TRIM25
分子名称: Tripartite motif-containing 25 variant
著者Pornillos, O, Sanchez, J.G, Okreglicka, K.
登録日2013-07-23
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
3H47
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BU of 3h47 by Molmil
X-ray Structure of Hexameric HIV-1 CA
分子名称: Capsid protein p24
著者Pornillos, O.
登録日2009-04-18
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structures of the hexameric building block of the HIV capsid.
Cell(Cambridge,Mass.), 137, 2009
3H4E
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BU of 3h4e by Molmil
X-ray Structure of Hexameric HIV-1 CA
分子名称: Capsid protein p24
著者Pornillos, O.
登録日2009-04-19
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献X-ray structures of the hexameric building block of the HIV capsid.
Cell(Cambridge,Mass.), 137, 2009
5EYA
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BU of 5eya by Molmil
TRIM25 RING domain in complex with Ubc13-Ub conjugate
分子名称: Polyubiquitin-B, Tripartite motif-containing 25 variant, Ubiquitin-conjugating enzyme E2 N, ...
著者Pornillos, O, Sanchez, J.G.
登録日2015-11-24
公開日2016-08-17
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
Cell Rep, 16, 2016
5VZV
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BU of 5vzv by Molmil
TRIM23 RING domain
分子名称: E3 ubiquitin-protein ligase TRIM23, ZINC ION
著者Pornillos, O, Dawidziak, D.
登録日2017-05-29
公開日2017-08-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.812 Å)
主引用文献Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.
Proteins, 85, 2017
1KPQ
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BU of 1kpq by Molmil
Structure of the Tsg101 UEV domain
分子名称: Tumor susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I.
登録日2002-01-02
公開日2002-05-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and functional interactions of the Tsg101 UEV domain.
EMBO J., 21, 2002
1KPP
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BU of 1kpp by Molmil
Structure of the Tsg101 UEV domain
分子名称: Tumor susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I.
登録日2002-01-02
公開日2002-05-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and functional interactions of the Tsg101 UEV domain.
EMBO J., 21, 2002
1M4P
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BU of 1m4p by Molmil
Structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP "late domain" peptide, DYANA Ensemble
分子名称: Gag Polyprotein, Tumor Susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I.
登録日2002-07-03
公開日2002-11-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein
Nat.Struct.Biol., 9, 2002
1M4Q
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BU of 1m4q by Molmil
STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A HIV-1 PTAP "LATE DOMAIN" PEPTIDE, CNS ENSEMBLE
分子名称: Gag Polyprotein, Tumor Susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I.
登録日2002-07-03
公開日2002-11-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein
Nat.Struct.Biol., 9, 2002
8TY6
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BU of 8ty6 by Molmil
Disulfide-stabilized HIV-1 CA hexamer in complex with PQBP1 Nt
分子名称: Capsid protein p24
著者Piacentini, J, Pornillos, O, Ganser-Pornillos, B.K.
登録日2023-08-24
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular Determinants of PQBP1 Binding to the HIV-1 Capsid Lattice.
J.Mol.Biol., 436, 2024
7R7P
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BU of 7r7p by Molmil
Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6)
分子名称: 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T.
登録日2021-06-25
公開日2023-02-15
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023

 

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