1B7D
 
 | | NEUROTOXIN (TS1) FROM BRAZILIAN SCORPION TITYUS SERRULATUS | | Descriptor: | PHOSPHATE ION, PROTEIN (NEUROTOXIN TS1) | | Authors: | Polikarpov, I, Sanches Jr, M.S, Marangoni, S, Toyama, M.H, Teplyakov, A. | | Deposit date: | 1999-01-21 | | Release date: | 1999-07-22 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Crystal structure of neurotoxin Ts1 from Tityus serrulatus provides insights into the specificity and toxicity of scorpion toxins.
J.Mol.Biol., 290, 1999
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4TUF
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8GF3
 | | Crystallographic structure from BlMan5_7 | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GH5 Mannanase, ... | | Authors: | Briganti, L, Araujo, E.A, Polikarpov, I. | | Deposit date: | 2023-03-07 | | Release date: | 2024-04-17 | | Last modified: | 2024-07-31 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Unravelling biochemical and structural features of Bacillus licheniformis GH5 mannanase using site-directed mutagenesis and high-resolution protein crystallography studies.
Int.J.Biol.Macromol., 274, 2024
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1HWU
 | | STRUCTURE OF PII PROTEIN FROM HERBASPIRILLUM SEROPEDICAE | | Descriptor: | PII PROTEIN | | Authors: | Benelli, E.M, Buck, M, Polikarpov, I, De Souza, E.M, Cruz, L.M, Pedrosa, F.O. | | Deposit date: | 2001-01-10 | | Release date: | 2003-06-17 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK.
Eur.J.Biochem., 269, 2002
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7M1R
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3SZ1
 | | Human PPAR gamma ligand binding domain in complex with luteolin and myristic acid | | Descriptor: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, MYRISTIC ACID, Peroxisome proliferator-activated receptor gamma, ... | | Authors: | Puhl, A.C, Bernardes, A, Polikarpov, I. | | Deposit date: | 2011-07-18 | | Release date: | 2012-03-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Mode of peroxisome proliferator-activated receptor gamma activation by luteolin.
Mol.Pharmacol., 81, 2012
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4DEW
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8UWS
 | | Cryo-EM structure of an Enterobacter GH43 Beta-Xylosidase: EcXyl43 | | Descriptor: | Beta-xylosidase, CALCIUM ION | | Authors: | Briganti, L, Godoy, A.S, Capetti, C.C.M, Portugal, R.V, Polikarpov, I. | | Deposit date: | 2023-11-08 | | Release date: | 2024-05-15 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (2.65 Å) | | Cite: | Cryo-EM structure of an Enterobacter GH43 Beta-Xylosidase: EcXyl43
To Be Published
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4DER
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4EMA
 | | Human peroxisome proliferator-activated receptor gamma in complex with rosiglitazone | | Descriptor: | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Peroxisome proliferator-activated receptor gamma | | Authors: | Liberato, M.V, Nascimento, A.S, Polikarpov, I. | | Deposit date: | 2012-04-11 | | Release date: | 2013-03-06 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.545 Å) | | Cite: | Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) Gamma activators and pan-PPAR partial agonists
Plos One, 7, 2012
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4OJ4
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6BUS
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8U4F
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8U4A
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8U49
 | | The Apo Crystal Structure of BlCel9A from Glycoside Hydrolase Family 9 | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | | Authors: | Araujo, E.A, Polikarpov, I. | | Deposit date: | 2023-09-10 | | Release date: | 2024-02-14 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular mechanism of cellulose depolymerization by the two-domain BlCel9A enzyme from the glycoside hydrolase family 9.
Carbohydr Polym, 329, 2024
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3TKM
 | | Crystal structure PPAR delta binding GW0742 | | Descriptor: | GLYCEROL, Peroxisome proliferator-activated receptor delta, {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid | | Authors: | Trivella, D.B.B, Batista, F.H, Polikarpov, I. | | Deposit date: | 2011-08-27 | | Release date: | 2012-07-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.953 Å) | | Cite: | Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding.
Plos One, 7, 2012
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8VG9
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5TOA
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1IG8
 | | Crystal Structure of Yeast Hexokinase PII with the correct amino acid sequence | | Descriptor: | SULFATE ION, hexokinase PII | | Authors: | Kuser, P.R, Krauchenco, S, Antunes, O.A, Polikarpov, I. | | Deposit date: | 2001-04-17 | | Release date: | 2001-05-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The high resolution crystal structure of yeast hexokinase PII with the correct primary sequence provides new insights into its mechanism of action.
J.Biol.Chem., 275, 2000
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1JV4
 | | Crystal structure of recombinant major mouse urinary protein (rmup) at 1.75 A resolution | | Descriptor: | 2-(SEC-BUTYL)THIAZOLE, CADMIUM ION, Major urinary protein 2 | | Authors: | Kuser, P.R, Franzoni, L, Ferrari, E, Spisni, A, Polikarpov, I. | | Deposit date: | 2001-08-28 | | Release date: | 2001-12-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The X-ray structure of a recombinant major urinary protein at 1.75 A resolution. A comparative study of X-ray and NMR-derived structures.
Acta Crystallogr.,Sect.D, 57, 2001
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4UCF
 | | Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose | | Descriptor: | BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, N-PROPANOL, ... | | Authors: | Godoy, A.S, Murakami, M.T, Camilo, C.M, Bernardes, A, Polikarpov, I. | | Deposit date: | 2014-12-03 | | Release date: | 2016-01-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Crystal Structure of Beta1-6-Galactosidase from Bifidobacterium Bifidum S17: Trimeric Architecture, Molecular Determinants of the Enzymatic Activity and its Inhibition by Alpha-Galactose.
FEBS J., 283, 2016
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4UOJ
 | | Structure of Fungal beta-mannosidase (GH2) from Trichoderma harzianum | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(3-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Muniz, J.R.C, Aparicio, R, Santos, J.C, Nascimento, A.S, Golubev, A.M, Polikarpov, I. | | Deposit date: | 2014-06-04 | | Release date: | 2014-07-09 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Insights Into the Structure and Function of Fungal Beta-Mannosidases from Glycoside Hydrolase Family 2 Based on Multiple Crystal Structures of the Trichoderma Harzianum Enzyme.
FEBS J., 281, 2014
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4USC
 | | Crystal structure of peroxidase from palm tree Chamaerops excelsa | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Bernardes, A, Santos, J.C, Textor, L.C, Cuadrado, N.H, Kostetsky, E.Y, Roig, M.G, Muniz, J.R.C, Shnyrov, V.L, Polikarpov, I. | | Deposit date: | 2014-07-07 | | Release date: | 2015-05-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure Analysis of Peroxidase from the Palm Tree Chamaerops Excelsa.
Biochimie, 111, 2015
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5DYR
 | | Structure of virulence-associated protein D (VapD) from Xylella fastidiosa | | Descriptor: | Virulence-associated protein D | | Authors: | Kochneva, M.V, dos Santos, M.L, dos Santos, C.A, de Souza, A.P, Polikarpov, I, Aparicio, R, Golubev, A.M. | | Deposit date: | 2015-09-25 | | Release date: | 2016-01-27 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of virulence-associated protein D (VapD) from Xylella fastidiosa
To Be Published
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6MVI
 | | Apo Cel45A from Neurospora crassa OR74A | | Descriptor: | Endoglucanase V | | Authors: | Kadowaki, M.A.S, Polikarpov, I. | | Deposit date: | 2018-10-25 | | Release date: | 2019-10-30 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural insights into the hydrolysis pattern and molecular dynamics simulations of GH45 subfamily a endoglucanase from Neurospora crassa OR74A.
Biochimie, 165, 2019
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