3SZ1
Human PPAR gamma ligand binding domain in complex with luteolin and myristic acid
Summary for 3SZ1
Entry DOI | 10.2210/pdb3sz1/pdb |
Related | 1PRG 3OM9 3PBA |
Descriptor | Peroxisome proliferator-activated receptor gamma, nonanoic acid, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, ... (5 entities in total) |
Functional Keywords | ppar gamma, nuclear receptor, luteolin, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 64300.81 |
Authors | Puhl, A.C.,Bernardes, A.,Polikarpov, I. (deposition date: 2011-07-18, release date: 2012-03-21, Last modification date: 2024-02-28) |
Primary citation | Puhl, A.C.,Bernardes, A.,Silveira, R.L.,Yuan, J.,Campos, J.L.,Saidemberg, D.M.,Palma, M.S.,Cvoro, A.,Ayers, S.D.,Webb, P.,Reinach, P.S.,Skaf, M.S.,Polikarpov, I. Mode of peroxisome proliferator-activated receptor gamma activation by luteolin. Mol.Pharmacol., 81:788-799, 2012 Cited by PubMed: 22391103DOI: 10.1124/mol.111.076216 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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