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PDB: 137 件
4MP0
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BU of 4mp0 by Molmil
Structure of a second nuclear PP1 Holoenzyme, crystal form 2
分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ...
著者Choy, M.S, Hieke, M, Peti, W, Page, R.
登録日2013-09-12
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1003 Å)
主引用文献Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MOY
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BU of 4moy by Molmil
Structure of a second nuclear PP1 Holoenzyme, crystal form 1
分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Choy, M.S, Hieke, M, Peti, W, Page, R.
登録日2013-09-12
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1953 Å)
主引用文献Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.
Proc.Natl.Acad.Sci.USA, 111, 2014
6OBP
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BU of 6obp by Molmil
Reconstituted PP1 holoenzyme
分子名称: CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ...
著者Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
登録日2019-03-21
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OBQ
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BU of 6obq by Molmil
PP1 H66K in complex with Microcystin LR
分子名称: MANGANESE (II) ION, Microcystin LR, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
著者Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
登録日2019-03-21
公開日2019-09-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
2KM6
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BU of 2km6 by Molmil
NMR structure of the NLRP7 Pyrin domain
分子名称: NACHT, LRR and PYD domains-containing protein 7
著者Pinheiro, A, Proell, M, Schwarzenbacher, R, Peti, W.
登録日2009-07-21
公開日2010-06-09
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the NLRP7 pyrin domain: insight into pyrin-pyrin-mediated effector domain signaling in innate immunity.
J.Biol.Chem., 285, 2010
2FN5
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BU of 2fn5 by Molmil
NMR Structure of the Neurabin PDZ domain (502-594)
分子名称: Neurabin-1
著者Dancheck, B, Peti, W.
登録日2006-01-10
公開日2007-01-09
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry, 46, 2007
2GLE
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BU of 2gle by Molmil
Solution structure of neurabin SAM domain
分子名称: Neurabin-1
著者Ju, T, Hudak, J, Peti, W.
登録日2006-04-04
公開日2007-03-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural characterization of the neurabin SAM domain
TO BE PUBLISHED
2LPE
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BU of 2lpe by Molmil
Solution NMR Structure of the KSR1 CA1-CA1a domain
分子名称: Kinase suppressor of Ras 1
著者Koveal, D, Peti, W, Page, R.
登録日2012-02-11
公開日2012-12-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A CC-SAM, for Coiled Coil Sterile a Motif, Domain Targets the Scaffold KSR-1 to Specific Sites in the Plasma Membrane
SCI.SIGNAL., 5, 2012
2L6A
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BU of 2l6a by Molmil
Three-dimensional structure of the N-terminal effector PYRIN domain of NLRP12
分子名称: NACHT, LRR and PYD domains-containing protein 12
著者Pinheiro, A.S, Peti, W.
登録日2010-11-17
公開日2011-11-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NLRP12 pyrin domain: structure, dynamics, and functional insights.
J.Mol.Biol., 413, 2011
1RDU
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BU of 1rdu by Molmil
NMR STRUCTURE OF A PUTATIVE NIFB PROTEIN FROM THERMOTOGA (TM1290), WHICH BELONGS TO THE DUF35 FAMILY
分子名称: conserved hypothetical protein
著者Etezady-Esfarjani, T, Herrmann, T, Peti, W, Klock, H.E, Lesley, S.A, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2003-11-06
公開日2004-07-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Structure Determination of the Hypothetical Protein TM1290 from Thermotoga Maritima using Automated NOESY Analysis.
J.Biomol.NMR, 29, 2004
1SMO
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BU of 1smo by Molmil
Crystal Structure of Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.47 .
分子名称: L(+)-TARTARIC ACID, triggering receptor expressed on myeloid cells 1
著者Kelker, M.S, Foss, T.R, Peti, W, Teyton, L, Kelly, J.W, Wilson, I.A.
登録日2004-03-09
公開日2004-09-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystal Structure of Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.47A.
J.Mol.Biol., 342, 2004
1T3V
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BU of 1t3v by Molmil
The NMR solution structure of TM1816
分子名称: conserved hypothetical protein
著者Columbus, L, Peti, W, Herrmann, T, Etazady, T, Klock, H, Lesley, S, Wuthrich, K, Joint Center for Structural Genomics (JCSG)
登録日2004-04-27
公開日2004-12-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR structure determination of the conserved hypothetical protein TM1816 from Thermotoga maritima.
Proteins, 60, 2005
6ALZ
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BU of 6alz by Molmil
Crystal structure of Protein Phosphatase 1 bound to the natural inhibitor Tautomycetin
分子名称: (2Z)-2-[(1R)-3-{[(2R,3S,4R,7S,8S,11S,13R,16E)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2017-08-08
公開日2017-11-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.208 Å)
主引用文献PP1:Tautomycetin Complex Reveals a Path toward the Development of PP1-Specific Inhibitors.
J. Am. Chem. Soc., 139, 2017
6ATD
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BU of 6atd by Molmil
Oxidized SHP2 forms a disulfide bond between Cys367 and Cys459
分子名称: PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 11
著者Page, R, Peti, W, Critton, D.A.
登録日2017-08-28
公開日2018-07-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Redox Regulation of a Gain-of-Function Mutation (N308D) in SHP2 Noonan Syndrome.
ACS Omega, 2, 2017
3E7B
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BU of 3e7b by Molmil
Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin inhibitor Tautomycin
分子名称: (2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10R)-10-{(2S,3S,6R,8S,9R)-3,9-dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undec-2-yl}-3,7-dihydroxy-2-methoxy-6-methyl-1-(1-methylethyl)-5-oxoundecyl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, AZIDE ION, CHLORIDE ION, ...
著者Kelker, M.S, Page, R, Peti, W.
登録日2008-08-18
公開日2008-11-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors
J.Mol.Biol., 385, 2009
3EGG
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BU of 3egg by Molmil
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Spinophilin
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MANGANESE (II) ION, ...
著者Ragusa, M.J, Page, R, Peti, W.
登録日2008-09-10
公開日2010-03-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
6BSR
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BU of 6bsr by Molmil
Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the benzylpenicillin bound form.
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Moon, T.M, D'Andrea, E.D, Peti, W, Page, R.
登録日2017-12-04
公開日2018-10-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
3FMY
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BU of 3fmy by Molmil
Structure of the C-terminal domain of the E. coli protein MQSA (YgiT/b3021)
分子名称: HTH-type transcriptional regulator MQSA (ygiT/b3021)
著者Page, R, Brown, B.L, Arruda, J.M, Peti, W.
登録日2008-12-22
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprised of a toxin homologous to RelE and an antitoxin with unique properties
Plos Pathog., 5, 2009
6CZO
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BU of 6czo by Molmil
The KNL1-PP1 Holoenzyme
分子名称: CASC5 protein, MANGANESE (II) ION, PHOSPHATE ION, ...
著者Bajaj, R, Peti, W, Page, R.
登録日2018-04-09
公開日2019-01-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献KNL1 Binding to PP1 and Microtubules Is Mutually Exclusive.
Structure, 26, 2018
6BSQ
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BU of 6bsq by Molmil
Enterococcus faecalis Penicillin Binding Protein 4 (PBP4)
分子名称: CHLORIDE ION, GLYCEROL, PBP4 protein
著者Moon, T.M, D'Andrea, E.D, Peti, W, Page, R.
登録日2017-12-04
公開日2018-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018
6DNO
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BU of 6dno by Molmil
Crystal structure of Protein Phosphatase 1 (PP1) bound to the muscle glycogen-targeting subunit (Gm)
分子名称: Microcystin-LR, Protein phosphatase 1 regulatory subunit 3A, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
著者Choy, M.S, Kumar, G.S, Peti, W, Page, R.
登録日2018-06-07
公開日2019-01-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme.
Sci Adv, 4, 2018
3E7A
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BU of 3e7a by Molmil
Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin Nodularin-R
分子名称: AZIDE ION, CHLORIDE ION, GLYCEROL, ...
著者Kelker, M.S, Page, R, Peti, W.
登録日2008-08-18
公開日2008-11-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors
J.Mol.Biol., 385, 2009
3EGH
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BU of 3egh by Molmil
Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1), the PP1 binding and PDZ domains of Spinophilin and the small natural molecular toxin Nodularin-R
分子名称: GLYCEROL, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ...
著者Ragusa, M.J, Page, R, Peti, W.
登録日2008-09-10
公開日2010-03-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
8DWK
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BU of 8dwk by Molmil
Inhibitor-3:PP1 reconstituted complex
分子名称: E3 ubiquitin-protein ligase PPP1R11, MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
著者Choy, M.S, Srivastava, G, Page, R, Peti, W.
登録日2022-08-01
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Inhibitor-3 inhibits Protein Phosphatase 1 via a metal binding dynamic protein-protein interaction.
Nat Commun, 14, 2023
8DWL
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BU of 8dwl by Molmil
Inhibitor-3:PP1 coexpressed complex
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase PPP1R11, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ...
著者Choy, M.S, Srivastava, G, Page, R, Peti, W.
登録日2022-08-01
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibitor-3 inhibits Protein Phosphatase 1 via a metal binding dynamic protein-protein interaction.
Nat Commun, 14, 2023

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