7ZPF
 
 | | Three-dimensional structure of AIP56, a short-trip single chain AB toxin from Photobacterium damselae subsp. piscicida. | | Descriptor: | Aip56, GLYCEROL, NICKEL (II) ION, ... | | Authors: | Lisboa, J, Pereira, P.J.B, dos Santos, N.M.S. | | Deposit date: | 2022-04-27 | | Release date: | 2023-05-10 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | Unconventional structure and mechanisms for membrane interaction and translocation of the NF-kappa B-targeting toxin AIP56.
Nat Commun, 14, 2023
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6FGM
 | | The NMR solution structure of the peptide AC12 from Hypsiboas raniceps | | Descriptor: | ALA-CYS-PHE-LEU-THR-ARG-LEU-GLY-THR-TYR-VAL-CYS | | Authors: | Popov, C.S.F.C, Simas, B.S, Goodfellow, B.J, Bocca, A.L, Andrade, P.B, Pereira, D, Valentao, P, Pereira, P.J.B, Rodrigues, J.E, Veloso Jr, P.H.H, Rezende, T.M.B. | | Deposit date: | 2018-01-11 | | Release date: | 2019-01-09 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Host-defense peptides AC12, DK16 and RC11 with immunomodulatory activity isolated from Hypsiboas raniceps skin secretion.
Peptides, 113, 2019
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5DAE
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3KIA
 | | Crystal structure of mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus | | Descriptor: | CHLORIDE ION, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. | | Deposit date: | 2009-11-01 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity
Mol.Microbiol., 79, 2011
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3F1Y
 | | Mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Mannosyl-3-phosphoglycerate synthase | | Authors: | Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. | | Deposit date: | 2008-10-28 | | Release date: | 2009-11-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity
Mol.Microbiol., 79, 2011
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7NZZ
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2JB9
 | | PhoB response regulator receiver domain constitutively-active double mutant D10A and D53E. | | Descriptor: | PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB | | Authors: | Ferrer-Orta, C, Arribas-Bosacoma, R, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M. | | Deposit date: | 2006-12-05 | | Release date: | 2007-01-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The X-Ray Crystal Structures of Two Constitutively Active Mutants of the E. Coli Phob Receiver Domain Give Insights Into Activation
J.Mol.Biol., 366, 2007
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2JBA
 | | PhoB response regulator receiver domain constitutively-active double mutant D53A and Y102C. | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB, SODIUM ION | | Authors: | Arribas-Bosacoma, R, Ferrer-Orta, C, Kim, S.-K, Blanco, A.G, Pereira, P.J.B, Gomis-Ruth, F.X, Wanner, B.L, Coll, M, Sola, M. | | Deposit date: | 2006-12-05 | | Release date: | 2007-01-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The X-Ray Crystal Structures of Two Constitutively Active Mutants of the Escherichia Coli Phob Receiver Domain Give Insights Into Activation.
J.Mol.Biol., 366, 2007
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5L6N
 | | Disulfated madanin-thrombin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin, SODIUM ION, ... | | Authors: | Ripoll-Rozada, J, Pereira, P.J.B. | | Deposit date: | 2016-05-30 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.627 Å) | | Cite: | Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors.
Nat Chem, 9, 2017
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5M3N
 | | HTRA2 wild-type structure | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Serine protease HTRA2, mitochondrial | | Authors: | Merski, M, Pereira, P.J.B, Macedo-Ribeiro, S. | | Deposit date: | 2016-10-15 | | Release date: | 2017-10-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.649 Å) | | Cite: | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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1TT6
 | | The orthorhombic crystal structure of transthyretin in complex with diethylstilbestrol | | Descriptor: | DIETHYLSTILBESTROL, GLYCEROL, SULFATE ION, ... | | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | | Deposit date: | 2004-06-22 | | Release date: | 2004-10-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors
J.Biol.Chem., 279, 2004
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1TZ8
 | | The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol | | Descriptor: | ACETATE ION, CARBONATE ION, DIETHYLSTILBESTROL, ... | | Authors: | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | | Deposit date: | 2004-07-09 | | Release date: | 2004-10-12 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors
J.Biol.Chem., 279, 2004
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7QSJ
 | | Methylmannose polysaccharide hydrolase MmpH from M. hassiacum | | Descriptor: | GLYCEROL, MAGNESIUM ION, Methylmannose polysaccharide hydrolase (MmpH), ... | | Authors: | Ripoll-Rozada, J, Manso, J.A, Pereira, P.J.B. | | Deposit date: | 2022-01-13 | | Release date: | 2023-01-25 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Self-recycling and partially conservative replication of mycobacterial methylmannose polysaccharides.
Commun Biol, 6, 2023
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7QSG
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6SQX
 | | Insights into a novel NlpC/P60 Endopeptidase from Photobacterium damselae subsp. piscicida | | Descriptor: | 1,2-ETHANEDIOL, BICARBONATE ION, CHLORIDE ION, ... | | Authors: | Lisboa, J, Pereira, P.J.B, dos Santos, N.M.S. | | Deposit date: | 2019-09-04 | | Release date: | 2020-09-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A Secreted NlpC/P60 Endopeptidase from Photobacterium damselae subsp. piscicida Cleaves the Peptidoglycan of Potentially Competing Bacteria.
Msphere, 6, 2021
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4IS4
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2I5P
 | | Crystal structure of glyceraldehyde-3-phosphate dehydrogenase isoform 1 from K. marxianus | | Descriptor: | BETA-MERCAPTOETHANOL, Glyceraldehyde-3-phosphate dehydrogenase 1, alpha-D-glucopyranose | | Authors: | Ferreira-da-Silva, F, Pereira, P.J.B, Gales, L, Moradas-Ferreira, P, Damas, A.M. | | Deposit date: | 2006-08-25 | | Release date: | 2006-09-12 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Crystal and Solution Structures of Glyceraldehyde-3-phosphate Dehydrogenase Reveal Different Quaternary Structures.
J.Biol.Chem., 281, 2006
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1H98
 | | New Insights into Thermostability of Bacterial Ferredoxins: High Resolution Crystal Structure of the Seven-Iron Ferredoxin from Thermus thermophilus | | Descriptor: | FE3-S4 CLUSTER, FERREDOXIN, IRON/SULFUR CLUSTER | | Authors: | Macedo-Ribeiro, S, Martins, B.M, Pereira, P.J.B, Buse, G, Huber, R, Soulimane, T. | | Deposit date: | 2001-03-05 | | Release date: | 2001-11-27 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | New Insights Into the Thermostability of Bacterial Ferredoxins: High-Resolution Crystal Structure of the Seven-Iron Ferredoxin from Thermus Thermophilus
J.Biol.Inorg.Chem., 6, 2001
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3O3P
 | | Crystal structure of R. xylanophilus MpgS in complex with GDP-Mannose | | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, ... | | Authors: | Macedo-Ribeiro, S, Pereira, P.J.B, Empadinhas, N, da Costa, M.S. | | Deposit date: | 2010-07-25 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.529 Å) | | Cite: | Functional and structural characterization of a novel mannosyl-3-phosphoglycerate synthase from Rubrobacter xylanophilus reveals its dual substrate specificity
Mol.Microbiol., 79, 2011
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1T31
 | | A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[3-({METHYL[1-(2-NAPHTHOYL)PIPERIDIN-4-YL]AMINO}CARBONYL)-2-NAPHTHYL]-1-(1-NAPHTHYL)-2-OXOETHYLPHOSPHONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | de Garavilla, L, Greco, M.N, Giardino, E.C, Wells, G.I, Haertlein, B.J, Kauffman, J.A, Corcoran, T.W, Derian, C.K, Eckardt, A.J, Abraham, W.M, Sukumar, N, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E, Andrade-Gordon, P, Damiano, B.P, Maryanoff, B.E, Pereira, P.J.B, Wang, Z.M, Rubin, H, Huber, R, Bode, W, Schechter, N.M, Strobl, S. | | Deposit date: | 2004-04-23 | | Release date: | 2005-03-01 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
J.Biol.Chem., 280, 2005
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6HWK
 | | Glucosamine kinase (crystal form B) | | Descriptor: | CHLORIDE ION, Glucosamine kinase, MAGNESIUM ION | | Authors: | Manso, J.A, Pereira, P.J.B. | | Deposit date: | 2018-10-12 | | Release date: | 2019-05-01 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.688 Å) | | Cite: | Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity.
Mbio, 10, 2019
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6G3N
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6HWL
 | | Glucosamine kinase in complex with glucosamine, ADP and inorganic phosphate | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Manso, J.A, Pereira, P.J.B. | | Deposit date: | 2018-10-12 | | Release date: | 2019-05-01 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.148 Å) | | Cite: | Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity.
Mbio, 10, 2019
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6HWJ
 | | Glucosamine kinase (crystal form A) | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Manso, J.A, Pereira, P.J.B. | | Deposit date: | 2018-10-12 | | Release date: | 2019-05-01 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.979 Å) | | Cite: | Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity.
Mbio, 10, 2019
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5TNZ
 | | HtrA2 S142D mutant | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SODIUM ION, Serine protease HTRA2, ... | | Authors: | Macedo-Ribeiro, S, Merski, M, Pereira, P.J.B. | | Deposit date: | 2016-10-15 | | Release date: | 2017-10-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2.
Cell Death Dis, 8, 2017
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