5L6N

Disulfated madanin-thrombin complex

Summary for 5L6N

• Entry DOI: 10.2210/pdb5l6n/pdb
• Descriptor: Prothrombin, Thrombin inhibitor madanin 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hydrolase, anticoagulant sulfotyrosine
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 38151.16

Authors

Ripoll-Rozada, J.,Pereira, P.J.B. (deposition date: 2016-05-30, release date: 2017-03-29, Last modification date: 2024-01-10)

• Primary citation: Thompson, R.E.,Liu, X.,Ripoll-Rozada, J.,Alonso-Garcia, N.,Parker, B.L.,Pereira, P.J.B.,Payne, R.J.; Tyrosine sulfation modulates activity of tick-derived thrombin inhibitors.; Nat Chem, 9:909-917, 2017; PubMed: 28837178; DOI: 10.1038/nchem.2744

Experimental method

X-RAY DIFFRACTION (1.627 Å)