4JT5
 
 | | mTORdeltaN-mLST8-pp242 complex | | 分子名称: | 2-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1H-indol-5-ol, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | | 著者 | Pavletich, N.P, Yang, H. | | 登録日 | 2013-03-22 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | | 主引用文献 | mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
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4JSX
 | | structure of mTORDeltaN-mLST8-Torin2 complex | | 分子名称: | 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2(1H)-one, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8 | | 著者 | Pavletich, N.P, Yang, H. | | 登録日 | 2013-03-22 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | mTOR kinase structure, mechanism and regulation.
Nature, 497, 2013
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4RIA
 | | FAN1 Nuclease bound to 5' phosphorylated nicked DNA | | 分子名称: | BARIUM ION, DNA (5'-D(*TP*TP*TP*TP*TP*TP*G*AP*GP*GP*CP*GP*TP*G)-3'), DNA (5'-D(P*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), ... | | 著者 | Pavletich, N.P, Wang, R. | | 登録日 | 2014-10-05 | | 公開日 | 2014-12-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
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4RID
 | | Human FAN1 nuclease | | 分子名称: | Fanconi-associated nuclease 1 | | 著者 | Pavletich, N.P, Wang, R. | | 登録日 | 2014-10-05 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
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4RIC
 | | FAN1 Nuclease bound to 5' hydroxyl (dT-dT) single flap DNA | | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*GP*GP*AP*GP*TP*CP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*TP*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), ... | | 著者 | Pavletich, N.P, Wang, R. | | 登録日 | 2014-10-05 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
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4RI9
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4RIB
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4RI8
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1ZAA
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3CMX
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3CMW
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3CMV
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3CMU
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7JY9
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7JY6
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7JY8
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7JY7
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1IYJ
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1J8F
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7SIC
 | | Human ATM Dimer | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM | | 著者 | Warren, C, Pavletich, N.P. | | 登録日 | 2021-10-13 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | Structure of the human ATM kinase and mechanism of Nbs1 binding.
Elife, 11, 2022
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7SID
 | | Human ATM Dimer Bound to Nbs1 | | 分子名称: | MAGNESIUM ION, Nibrin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Warren, C, Pavletich, N.P. | | 登録日 | 2021-10-13 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | Structure of the human ATM kinase and mechanism of Nbs1 binding.
Elife, 11, 2022
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1D5R
 | | Crystal Structure of the PTEN Tumor Suppressor | | 分子名称: | L(+)-TARTARIC ACID, PHOSPHOINOSITIDE PHOSPHATASE PTEN | | 著者 | Lee, J.O, Yang, H, Georgescu, M.-M, Di Cristofano, A, Pavletich, N.P. | | 登録日 | 1999-10-11 | | 公開日 | 1999-11-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Cell(Cambridge,Mass.), 99, 1999
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1D5F
 | | STRUCTURE OF E6AP: INSIGHTS INTO UBIQUITINATION PATHWAY | | 分子名称: | E6AP HECT CATALYTIC DOMAIN, E3 LIGASE | | 著者 | Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P. | | 登録日 | 1999-10-07 | | 公開日 | 1999-11-17 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade.
Science, 286, 1999
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1CF7
 | | STRUCTURAL BASIS OF DNA RECOGNITION BY THE HETERODIMERIC CELL CYCLE TRANSCRIPTION FACTOR E2F-DP | | 分子名称: | DNA (5'-D(*AP*TP*TP*TP*TP*CP*GP*CP*GP*CP*GP*GP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*AP*AP*CP*CP*GP*CP*GP*CP*GP*AP*AP*AP*A)-3'), PROTEIN (TRANSCRIPTION FACTOR DP-2), ... | | 著者 | Zheng, N, Fraenkel, E, Pabo, C.O, Pavletich, N.P. | | 登録日 | 1999-03-24 | | 公開日 | 1999-04-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP.
Genes Dev., 13, 1999
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6U2U
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