7P9V
 
 | | Cryo EM structure of System XC- | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter | | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | 登録日 | 2021-07-28 | | 公開日 | 2021-11-17 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Molecular basis for redox control by the human cystine/glutamate antiporter system xc .
Nat Commun, 12, 2021
|
|
7P9U
 | | Cryo EM structure of System XC- in complex with glutamate | | 分子名称: | 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter, GLUTAMIC ACID | | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | 登録日 | 2021-07-28 | | 公開日 | 2021-11-17 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Molecular basis for redox control by the human cystine/glutamate antiporter system xc .
Nat Commun, 12, 2021
|
|
7BC6
 | | Cryo-EM structure of the outward open proton coupled folate transporter at pH 7.5 | | 分子名称: | Proton-coupled folate transporter, nanobody | | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | 登録日 | 2020-12-18 | | 公開日 | 2021-05-12 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of antifolate recognition and transport by PCFT.
Nature, 595, 2021
|
|
7BC7
 | | Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed | | 分子名称: | 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, Proton-coupled folate transporter, nanobody | | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | 登録日 | 2020-12-18 | | 公開日 | 2021-05-12 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of antifolate recognition and transport by PCFT.
Nature, 595, 2021
|
|
7NQK
 | | Cryo-EM structure of the mammalian peptide transporter PepT2 | | 分子名称: | Solute carrier family 15 member 2, nanobody | | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | 登録日 | 2021-03-01 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-10-13 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of PepT2 reveals structural basis for proton-coupled peptide and prodrug transport in mammals.
Sci Adv, 7, 2021
|
|
8BVS
 | | Cryo-EM structure of rat SLC22A6 bound to tenofovir | | 分子名称: | CHLORIDE ION, Solute carrier family 22 member 6, Synthetic nanobody (Sybody), ... | | 著者 | Parker, J.L, Kato, T, Newstead, S. | | 登録日 | 2022-12-05 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8BVR
 | |
8BVT
 | |
8BW7
 | | Cryo-EM structure of rat SLC22A6 bound to alpha-ketoglutaric acid | | 分子名称: | 2-OXOGLUTARIC ACID, CHLORIDE ION, Solute carrier family 22 member 6, ... | | 著者 | Parker, J.L, Kato, T, Newstead, S. | | 登録日 | 2022-12-06 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
7ZKW
 | |
8APY
 | |
8P6A
 | |
8OMU
 | |
5A2O
 | |
5A2N
 | |
6QSK
 | |
7OXE
 | |
6ZXR
 | |
7NVH
 | | Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis | | 分子名称: | Lauryl Maltose Neopentyl Glycol, Trehalose monomycolate exporter MmpL3 | | 著者 | Adams, O, Deme, J.C, Parker, J.L, Lea, S.M, Newstead, S. | | 登録日 | 2021-03-15 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target.
Structure, 29, 2021
|
|
4D2B
 | | Structure of a ligand free POT family peptide transporter | | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, DI-OR TRIPEPTIDE:H+ SYMPORTER, ... | | 著者 | Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S. | | 登録日 | 2014-05-09 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
|
|
4D2C
 | | Structure of a di peptide bound POT family peptide transporter | | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... | | 著者 | Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S. | | 登録日 | 2014-05-09 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
|
|
4D2D
 | | Structure of a tri peptide bound POT family peptide transporter | | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE-TRIPEPTIDE, ... | | 著者 | Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S. | | 登録日 | 2014-05-09 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.522 Å) | | 主引用文献 | Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
|
|
5OGK
 | |
5OGE
 | |
1OB9
 | | Holliday Junction Resolving Enzyme | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, HOLLIDAY JUNCTION RESOLVASE | | 著者 | Middleton, C.L, Parker, J.L, Richard, D.J, White, M.F, Bond, C.S. | | 登録日 | 2003-01-28 | | 公開日 | 2004-10-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Substrate Recognition and Catalysis by the Holliday Junction Resolving Enzyme Hje.
Nucleic Acids Res., 32, 2004
|
|
