7NVH

Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis

Summary for 7NVH

Entry DOI	10.2210/pdb7nvh/pdb
EMDB information	12604
Descriptor	Trehalose monomycolate exporter MmpL3, 2-decyl-2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside (2 entities in total)
Functional Keywords	transporter, membrane protein
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	83530.80
Authors	Adams, O.,Deme, J.C.,Parker, J.L.,Lea, S.M.,Newstead, S. (deposition date: 2021-03-15, release date: 2021-06-16, Last modification date: 2022-12-21)
Primary citation	Adams, O.,Deme, J.C.,Parker, J.L.,Fowler, P.W.,Lea, S.M.,Newstead, S. Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target. Structure, 29:1182-1191.e4, 2021 Cited by PubMed: 34242558 DOI: 10.1016/j.str.2021.06.013 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.02 Å)

Structure validation