7NVH

Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	binding site for residue AV0 A 801

Chain	Residue
A	GLN40
A	VAL169
A	THR174
A	ILE177
A	HIS234
A	TYR235
A	PHE236
A	ILE422
A	GLN437
A	ARG448
A	ASN450
A	SER41
A	GLU548
A	TYR44
A	VAL51
A	SER54
A	ASP58
A	ASP139
A	GLY165
A	LEU166

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	79
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"UniProtKB","id":"A0QP27","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	240
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	316
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"UniProtKB","id":"A0QP27","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"A0QP27","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	4
Details	Site: {"description":"Part of the proton-transportation channel","evidences":[{"source":"UniProtKB","id":"A0QP27","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Part of the proton transportation network","evidences":[{"source":"UniProtKB","id":"A0QP27","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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