7P9V

Cryo EM structure of System XC-

Summary for 7P9V

• Entry DOI: 10.2210/pdb7p9v/pdb
• Related: 7P9U
• EMDB information: 13266 13267
• Descriptor: 4F2 cell-surface antigen heavy chain, Cystine/glutamate transporter, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: transporter glutamate cystine, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 127326.08

Authors

Parker, J.L.,Deme, J.C.,Lea, S.M.,Newstead, S. (deposition date: 2021-07-28, release date: 2021-11-17, Last modification date: 2022-02-02)

• Primary citation: Parker, J.L.,Deme, J.C.,Kolokouris, D.,Kuteyi, G.,Biggin, P.C.,Lea, S.M.,Newstead, S.; Molecular basis for redox control by the human cystine/glutamate antiporter system xc .; Nat Commun, 12:7147-7147, 2021; PubMed: 34880232; DOI: 10.1038/s41467-021-27414-1

Experimental method

ELECTRON MICROSCOPY (3.4 Å)