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PDB: 163 件

4DNI
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Structure of Editosome protein
分子名称: Fusion protein of RNA-editing complex proteins MP42 and MP18
著者Park, Y.-J, Hol, W.
登録日2012-02-08
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds.
J.Struct.Biol., 180, 2012
4DK6
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Structure of Editosome protein
分子名称: RNA-editing complex protein MP81, single domain antibody VHH
著者Park, Y.-J, Hol, W.
登録日2012-02-03
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
7TAT
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SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2021-12-21
公開日2022-01-12
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry.
Science, 375, 2022
6Q04
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MERS-CoV S structure in complex with 5-N-acetyl neuraminic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6Q06
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MERS-CoV S structure in complex with 2,3-sialyl-N-acetyl-lactosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6Q05
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MERS-CoV S structure in complex with sialyl-lewisX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6Q07
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MERS-CoV S structure in complex with 2,6-sialyl-N-acetyl-lactosamine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Park, Y.J, Walls, A.C, Wang, Z, Sauer, M, Li, W, Tortorici, M.A, Bosch, B.J, DiMaio, F.D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-08-01
公開日2019-12-11
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
8FXC
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SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-01-24
公開日2023-10-04
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8FXB
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SARS-CoV-2 XBB.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-01-24
公開日2023-10-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8S9G
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SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Fab Heavy chain, ...
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2023-03-28
公開日2023-10-04
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
7WI1
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The mutant variant of PNGM-1, H93 was substituuted for alanine to study metal coordination
分子名称: Metallo-beta-lactamase PNGM-1, ZINC ION
著者Park, Y.S, Kang, L.W, Lee, J.H.
登録日2022-01-01
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural Study of Metal Binding and Coordination in Ancient Metallo-beta-Lactamase PNGM-1 Variants.
Int J Mol Sci, 21, 2020
5ZZ5
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BU of 5zz5 by Molmil
Redox-sensing transcriptional repressor Rex
分子名称: GLYCEROL, Redox-sensing transcriptional repressor Rex
著者Park, Y.W, Jang, Y.Y, Joo, H.K, Lee, J.Y.
登録日2018-05-30
公開日2018-11-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of Redox-sensing Transcriptional Repressor Rex from Thermotoga maritima
Sci Rep, 8, 2018
7R7N
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SARS-CoV-2 spike in complex with the S2D106 neutralizing antibody Fab fragment (local refinement of the RBD and S2D106)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2D106 FAB heavy chain, S2D106 FAB light chain, ...
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-06-25
公開日2021-07-21
最終更新日2021-09-15
実験手法ELECTRON MICROSCOPY (3.95 Å)
主引用文献SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
7TAS
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BU of 7tas by Molmil
SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (local refinement of the RBD and S2K146)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, S2K146 Fab light chain, ...
著者Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-12-21
公開日2022-01-12
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry.
Science, 375, 2022
2N50
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BU of 2n50 by Molmil
Novel Structural Components Contribute to the High Thermal Stability of Acyl Carrier Protein from Enterococcus faecalis
分子名称: Acyl carrier protein
著者Park, Y, Jung, M, Song, H, Jeong, K, Kim, Y.
登録日2015-07-02
公開日2015-12-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Novel Structural Components Contribute to the High Thermal Stability of Acyl Carrier Protein from Enterococcus faecalis.
J. Biol. Chem., 291, 2016
3STB
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BU of 3stb by Molmil
A complex of two editosome proteins and two nanobodies
分子名称: MP18 RNA editing complex protein, RNA-editing complex protein MP42, single domain antibody VHH
著者Park, Y.-J, Hol, W.
登録日2011-07-09
公開日2011-11-02
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody.
Nucleic Acids Res., 40, 2012
1F3V
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BU of 1f3v by Molmil
Crystal structure of the complex between the N-terminal domain of TRADD and the TRAF domain of TRAF2
分子名称: TUMOR NECROSIS FACTOR RECEPTOR TYPE 1 ASSOCIATED DEATH DOMAIN PROTEIN, TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEIN
著者Park, Y.C, Ye, H, Hsia, C, Segal, D, Rich, R, Liou, H.-C, Myszka, D, Wu, H.
登録日2000-06-06
公開日2000-09-06
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction.
Cell(Cambridge,Mass.), 101, 2000
3T1I
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BU of 3t1i by Molmil
Crystal Structure of Human Mre11: Understanding Tumorigenic Mutations
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Double-strand break repair protein MRE11A, GLYCEROL, ...
著者Park, Y.B, Chae, J, Kim, Y, Cho, Y.
登録日2011-07-22
公開日2011-11-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human mre11: understanding tumorigenic mutations
Structure, 19, 2011
3K81
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Structure of the central interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies
分子名称: MP18 RNA editing complex protein, Single strand antibody VHH domain
著者Park, Y.-J, Hol, W.
登録日2009-10-13
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
2ZD7
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BU of 2zd7 by Molmil
The structure of VPS75 (Vacuolar protein sorting-associated protein 75)
分子名称: EVDLPLSDEEPSS, Vacuolar protein sorting-associated protein 75
著者Park, Y.J, Luger, K.
登録日2007-11-20
公開日2008-08-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Histone chaperone specificity in Rtt109 activation.
Nat.Struct.Mol.Biol., 15, 2008
5CJ9
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BU of 5cj9 by Molmil
Bacillus halodurans Arginine repressor, ArgR
分子名称: Arginine repressor, S-1,2-PROPANEDIOL
著者Park, Y.W, Kang, J, Yeo, H.Y, Lee, J.Y.
登録日2015-07-14
公開日2016-06-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.409 Å)
主引用文献Structural Analysis and Insights into the Oligomeric State of an Arginine-Dependent Transcriptional Regulator from Bacillus halodurans.
Plos One, 11, 2016
5E9F
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Structural insights of isocitrate lyases from Magnaporthe oryzae
分子名称: Isocitrate lyase, MAGNESIUM ION
著者Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S.
登録日2015-10-15
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum
J.Struct.Biol., 194, 2016
5E9H
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Structural insights of isocitrate lyases from Fusarium graminearum
分子名称: Isocitrate lyase, MALONATE ION, MANGANESE (II) ION
著者Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S.
登録日2015-10-15
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum
J.Struct.Biol., 194, 2016
5E9G
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Structural insights of isocitrate lyases from Magnaporthe oryzae
分子名称: GLYCEROL, GLYOXYLIC ACID, Isocitrate lyase, ...
著者Park, Y, Cho, Y, Lee, Y.-H, Lee, Y.-W, Rhee, S.
登録日2015-10-15
公開日2016-04-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure and functional analysis of isocitrate lyases from Magnaporthe oryzae and Fusarium graminearum
J.Struct.Biol., 194, 2016
7E75
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Crystal structure of human ERK2 mutant (G37C)
分子名称: Mitogen-activated protein kinase 1
著者Park, Y.S, Kim, M, Ryu, S.E.
登録日2021-02-25
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.481 Å)
主引用文献Structural mechanism of inhibitor-resistance by ERK2 mutations
Biodesign, 9, 2021

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