6Q04

MERS-CoV S structure in complex with 5-N-acetyl neuraminic acid

Summary for 6Q04

Entry DOI	10.2210/pdb6q04/pdb
EMDB information	20542
Descriptor	Spike glycoprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywords	coronavirus, spike glycoprotein, mers-cov, membrane fusion, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
Biological source	Human betacoronavirus 2c EMC/2012
Total number of polymer chains	3
Total formula weight	474928.34
Authors	Park, Y.J.,Walls, A.C.,Wang, Z.,Sauer, M.,Li, W.,Tortorici, M.A.,Bosch, B.J.,DiMaio, F.D.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-08-01, release date: 2019-12-11, Last modification date: 2020-07-29)
Primary citation	Park, Y.J.,Walls, A.C.,Wang, Z.,Sauer, M.M.,Li, W.,Tortorici, M.A.,Bosch, B.J.,DiMaio, F.,Veesler, D. Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors. Nat.Struct.Mol.Biol., 26:1151-1157, 2019 Cited by PubMed: 31792450 DOI: 10.1038/s41594-019-0334-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation